Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085260646> ?p ?o ?g. }
- W2085260646 abstract "Abstract The competitive binding affinities of thirteen 7-substituted-2,3,-dichlorodibenzo-p-dioxins to the human Ah placental cytosolic Ah receptor were determined versus [ 3 H ]-2,3,7,8- tetrachlorodibenzo -p- dioxin (TCDD) as the radioligand. Multiple parameter linear regression analysis of the competitive binding EC50 values for these compounds gave the following equation: pEC 50 (M) =6.246+1.632 π − 1.764σ m° + 1.282 HB were π is the substituent lipophilicity, σm° the meta-directing electronegativity and HB the hydrogen binding capacity. The equation obtained using human placental receptor was different than correlations previously derived for the binding of the same series of compounds to the rat, mouse, guinea pig or hamster cytosolic Ah receptor, providing further evidence for interspecies differences in the properties of the Ah receptor protein." @default.
- W2085260646 created "2016-06-24" @default.
- W2085260646 creator A5017685499 @default.
- W2085260646 creator A5050491250 @default.
- W2085260646 creator A5053555017 @default.
- W2085260646 creator A5053755691 @default.
- W2085260646 creator A5078970144 @default.
- W2085260646 creator A5084967408 @default.
- W2085260646 date "1990-01-01" @default.
- W2085260646 modified "2023-09-26" @default.
- W2085260646 title "7-Substituted-2,3-dichlorodibenzo-p-dioxins as competitive ligands for the Ah receptor: Quantitative structure-activity relationships (QSARs) and a comparison of human receptor with Ah receptor from rodents" @default.
- W2085260646 cites W1505278126 @default.
- W2085260646 cites W1525217085 @default.
- W2085260646 cites W1577296862 @default.
- W2085260646 cites W1586026016 @default.
- W2085260646 cites W1895297695 @default.
- W2085260646 cites W1973543984 @default.
- W2085260646 cites W1979692051 @default.
- W2085260646 cites W1984860427 @default.
- W2085260646 cites W1993726991 @default.
- W2085260646 cites W2020991956 @default.
- W2085260646 cites W2024480573 @default.
- W2085260646 cites W2032520822 @default.
- W2085260646 cites W2130538892 @default.
- W2085260646 cites W2162067613 @default.
- W2085260646 cites W2179567193 @default.
- W2085260646 doi "https://doi.org/10.1016/0045-6535(90)90249-s" @default.
- W2085260646 hasPublicationYear "1990" @default.
- W2085260646 type Work @default.
- W2085260646 sameAs 2085260646 @default.
- W2085260646 citedByCount "6" @default.
- W2085260646 countsByYear W20852606462015 @default.
- W2085260646 crossrefType "journal-article" @default.
- W2085260646 hasAuthorship W2085260646A5017685499 @default.
- W2085260646 hasAuthorship W2085260646A5050491250 @default.
- W2085260646 hasAuthorship W2085260646A5053555017 @default.
- W2085260646 hasAuthorship W2085260646A5053755691 @default.
- W2085260646 hasAuthorship W2085260646A5078970144 @default.
- W2085260646 hasAuthorship W2085260646A5084967408 @default.
- W2085260646 hasConcept C107824862 @default.
- W2085260646 hasConcept C126322002 @default.
- W2085260646 hasConcept C134018914 @default.
- W2085260646 hasConcept C170493617 @default.
- W2085260646 hasConcept C181199279 @default.
- W2085260646 hasConcept C185592680 @default.
- W2085260646 hasConcept C201399114 @default.
- W2085260646 hasConcept C2776885963 @default.
- W2085260646 hasConcept C2778575167 @default.
- W2085260646 hasConcept C2778689049 @default.
- W2085260646 hasConcept C3019856697 @default.
- W2085260646 hasConcept C55493867 @default.
- W2085260646 hasConcept C67847695 @default.
- W2085260646 hasConcept C71240020 @default.
- W2085260646 hasConcept C71924100 @default.
- W2085260646 hasConcept C86803240 @default.
- W2085260646 hasConcept C86811712 @default.
- W2085260646 hasConcept C98539663 @default.
- W2085260646 hasConceptScore W2085260646C107824862 @default.
- W2085260646 hasConceptScore W2085260646C126322002 @default.
- W2085260646 hasConceptScore W2085260646C134018914 @default.
- W2085260646 hasConceptScore W2085260646C170493617 @default.
- W2085260646 hasConceptScore W2085260646C181199279 @default.
- W2085260646 hasConceptScore W2085260646C185592680 @default.
- W2085260646 hasConceptScore W2085260646C201399114 @default.
- W2085260646 hasConceptScore W2085260646C2776885963 @default.
- W2085260646 hasConceptScore W2085260646C2778575167 @default.
- W2085260646 hasConceptScore W2085260646C2778689049 @default.
- W2085260646 hasConceptScore W2085260646C3019856697 @default.
- W2085260646 hasConceptScore W2085260646C55493867 @default.
- W2085260646 hasConceptScore W2085260646C67847695 @default.
- W2085260646 hasConceptScore W2085260646C71240020 @default.
- W2085260646 hasConceptScore W2085260646C71924100 @default.
- W2085260646 hasConceptScore W2085260646C86803240 @default.
- W2085260646 hasConceptScore W2085260646C86811712 @default.
- W2085260646 hasConceptScore W2085260646C98539663 @default.
- W2085260646 hasLocation W20852606461 @default.
- W2085260646 hasOpenAccess W2085260646 @default.
- W2085260646 hasPrimaryLocation W20852606461 @default.
- W2085260646 hasRelatedWork W1910964268 @default.
- W2085260646 hasRelatedWork W1974868790 @default.
- W2085260646 hasRelatedWork W1977523985 @default.
- W2085260646 hasRelatedWork W1983725146 @default.
- W2085260646 hasRelatedWork W1988656550 @default.
- W2085260646 hasRelatedWork W2024942980 @default.
- W2085260646 hasRelatedWork W2031934729 @default.
- W2085260646 hasRelatedWork W2042776325 @default.
- W2085260646 hasRelatedWork W2042870001 @default.
- W2085260646 hasRelatedWork W2072399553 @default.
- W2085260646 hasRelatedWork W2082237875 @default.
- W2085260646 hasRelatedWork W2088165774 @default.
- W2085260646 hasRelatedWork W2116537475 @default.
- W2085260646 hasRelatedWork W2131243914 @default.
- W2085260646 hasRelatedWork W2146855364 @default.
- W2085260646 hasRelatedWork W2402152594 @default.
- W2085260646 hasRelatedWork W2415800624 @default.
- W2085260646 hasRelatedWork W2425791736 @default.
- W2085260646 hasRelatedWork W2787417802 @default.
- W2085260646 hasRelatedWork W2949759959 @default.
- W2085260646 isParatext "false" @default.
- W2085260646 isRetracted "false" @default.