FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085264811> ?p ?o ?g. }

• W2085264811 endingPage "365" @default.
• W2085264811 startingPage "360" @default.
• W2085264811 abstract "Angiogenic cytokines fms-like tyrosine kinase-1(sFlt-1) and placental growth factor (PlGF) are associated with increased risk for cardiovascular disease (CVD) in the general population. In this study we examine the association between these vascular endothelial factors and atherosclerosis, cardiovascular outcome, and mortality in chronic kidney disease (CKD) patients.Serum level of PlGF and sFlt-1 were measured in 301 patients with CKD, who were followed for up to 4 years. Primary outcomes were CV events and all-cause mortality. Carotid-intima media thickness (CIMT) was used as marker of atherosclerosis. Kaplan-Meier survival curves and the Cox proportional hazard model were used to assess the association of biomarkers and clinical outcomes.Mean (SD) PlGF and sFlt-1 were 5.45 ng/ml (3.76) and 68.6 (28.0) pg/ml, respectively. During the follow up time, 60 patients (19.9%) experienced CV events and 22 patients (7.3%) died. Compared with low PlGF, patients with PlGF above median level had higher CV events (12.7% vs. 27.2%, p = 0.002) and mortality (2.0% vs. 12.6%, p < 0.001). The associations of PlGF and sFlt-1 with CV events were not statistically significant in the fully adjusted model. Higher PlGF was associated with greater death risk (HR = 5.22, 95% CI: 1.49-18.33, p = 0.01), which was robust to adjustment for sFlt-1 and other risk factors. Elevated sFlt-1 level was also an independent predictor of mortality (HR 3.41, 95% CI: 1.49-9.51, p = 0.019).In CKD patients not yet on dialysis, higher serum level of PlGF and sFlt-1 are associated with increased mortality, but not CV events." @default.
• W2085264811 created "2016-06-24" @default.
• W2085264811 creator A5011285126 @default.
• W2085264811 creator A5012419218 @default.
• W2085264811 creator A5018412357 @default.
• W2085264811 creator A5018765344 @default.
• W2085264811 creator A5023108470 @default.
• W2085264811 creator A5026884173 @default.
• W2085264811 creator A5029187057 @default.
• W2085264811 creator A5037132477 @default.
• W2085264811 creator A5045618681 @default.
• W2085264811 creator A5049261258 @default.
• W2085264811 creator A5052946285 @default.
• W2085264811 date "2014-10-01" @default.
• W2085264811 modified "2023-10-10" @default.
• W2085264811 title "Association of vascular endothelial factors with cardiovascular outcome and mortality in chronic kidney disease patients: A 4-year cohort study" @default.
• W2085264811 cites W1561059299 @default.
• W2085264811 cites W1579207055 @default.
• W2085264811 cites W1985712533 @default.
• W2085264811 cites W1986832053 @default.
• W2085264811 cites W1997300200 @default.
• W2085264811 cites W2007048225 @default.
• W2085264811 cites W2015131055 @default.
• W2085264811 cites W2016920395 @default.
• W2085264811 cites W2023272495 @default.
• W2085264811 cites W2029313468 @default.
• W2085264811 cites W2029763523 @default.
• W2085264811 cites W2037433096 @default.
• W2085264811 cites W2044760298 @default.
• W2085264811 cites W2048818094 @default.
• W2085264811 cites W2054621026 @default.
• W2085264811 cites W2056144871 @default.
• W2085264811 cites W2076424556 @default.
• W2085264811 cites W2078177094 @default.
• W2085264811 cites W2088009966 @default.
• W2085264811 cites W2089273260 @default.
• W2085264811 cites W2092074451 @default.
• W2085264811 cites W2093044616 @default.
• W2085264811 cites W2097960717 @default.
• W2085264811 cites W2098389898 @default.
• W2085264811 cites W2112260972 @default.
• W2085264811 cites W2114396087 @default.
• W2085264811 cites W2143180984 @default.
• W2085264811 cites W2144846819 @default.
• W2085264811 cites W2145632027 @default.
• W2085264811 cites W2155739651 @default.
• W2085264811 cites W2160966717 @default.
• W2085264811 cites W2162598670 @default.
• W2085264811 cites W2164776005 @default.
• W2085264811 cites W2169896560 @default.
• W2085264811 cites W2410272249 @default.
• W2085264811 doi "https://doi.org/10.1016/j.atherosclerosis.2014.07.026" @default.
• W2085264811 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4327843" @default.
• W2085264811 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25128974" @default.
• W2085264811 hasPublicationYear "2014" @default.
• W2085264811 type Work @default.
• W2085264811 sameAs 2085264811 @default.
• W2085264811 citedByCount "12" @default.
• W2085264811 countsByYear W20852648112015 @default.
• W2085264811 countsByYear W20852648112016 @default.
• W2085264811 countsByYear W20852648112017 @default.
• W2085264811 countsByYear W20852648112019 @default.
• W2085264811 countsByYear W20852648112021 @default.
• W2085264811 countsByYear W20852648112022 @default.
• W2085264811 crossrefType "journal-article" @default.
• W2085264811 hasAuthorship W2085264811A5011285126 @default.
• W2085264811 hasAuthorship W2085264811A5012419218 @default.
• W2085264811 hasAuthorship W2085264811A5018412357 @default.
• W2085264811 hasAuthorship W2085264811A5018765344 @default.
• W2085264811 hasAuthorship W2085264811A5023108470 @default.
• W2085264811 hasAuthorship W2085264811A5026884173 @default.
• W2085264811 hasAuthorship W2085264811A5029187057 @default.
• W2085264811 hasAuthorship W2085264811A5037132477 @default.
• W2085264811 hasAuthorship W2085264811A5045618681 @default.
• W2085264811 hasAuthorship W2085264811A5049261258 @default.
• W2085264811 hasAuthorship W2085264811A5052946285 @default.
• W2085264811 hasBestOaLocation W20852648112 @default.
• W2085264811 hasConcept C126322002 @default.
• W2085264811 hasConcept C167734588 @default.
• W2085264811 hasConcept C207103383 @default.
• W2085264811 hasConcept C2776871010 @default.
• W2085264811 hasConcept C2777025900 @default.
• W2085264811 hasConcept C2778653478 @default.
• W2085264811 hasConcept C2779184299 @default.
• W2085264811 hasConcept C2908647359 @default.
• W2085264811 hasConcept C44249647 @default.
• W2085264811 hasConcept C50382708 @default.
• W2085264811 hasConcept C71924100 @default.
• W2085264811 hasConcept C72563966 @default.
• W2085264811 hasConcept C90924648 @default.
• W2085264811 hasConcept C99454951 @default.
• W2085264811 hasConceptScore W2085264811C126322002 @default.
• W2085264811 hasConceptScore W2085264811C167734588 @default.
• W2085264811 hasConceptScore W2085264811C207103383 @default.
• W2085264811 hasConceptScore W2085264811C2776871010 @default.
• W2085264811 hasConceptScore W2085264811C2777025900 @default.
• W2085264811 hasConceptScore W2085264811C2778653478 @default.
• W2085264811 hasConceptScore W2085264811C2779184299 @default.

• next