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• W2085282616 startingPage "271" @default.
• W2085282616 abstract "Thrombomodulin (TM) has been described as a marker of endothelial injury in atherosclerosis. The role of TM as a predictor of PAD severity is to be proven. The goal of the present study is to compare the level of plasmatic (TMp) in patients with intermittent claudication with patients with critical ischemia in the lower limbs.TMp was measured using ELISA in the plasma of 41 patients with intermittent claudication degree 1 and in 40 patients presenting critical ischemia in the lower limbs degrees 2 and 3, according to TASC. The hypotheses of normality and homogeneity of the variance had been proven via Shapiro-Wilk and Levene tests, respectively. The comparison of the TMp between the groups was done using the t-Student test.No statistically significant difference was observed. The average levels of TMp for intermittent claudication were 5.2 ng/ml (0.78-13.61 ng/ml) and TMp for critical ischemia in the lower limbs were 6.34 (0.82-18.22 ng/ml) where p=0.265.TMp does not seem to be an appropriate marker for PAD severity." @default.
• W2085282616 created "2016-06-24" @default.
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• W2085282616 date "2006-01-01" @default.
• W2085282616 modified "2023-10-12" @default.
• W2085282616 title "Relationship between soluble thrombomodulin in patients with intermittent claudication and critical ischemia" @default.
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• W2085282616 doi "https://doi.org/10.1016/j.thromres.2005.03.010" @default.
• W2085282616 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15890390" @default.
• W2085282616 hasPublicationYear "2006" @default.
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