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- W2085283608 abstract "The mitotic spindle checkpoint arrests cells in metaphase until all kinetochores arecorrectly attached to spindle fibres. In a search for new components of the spindlecheckpoint, based on protein interaction, we have identified mouse Telomeric RepeatBinding Factor 1 (Trf1) as a protein that interacts directly with the spindle checkpointprotein Mad1 and the mitotic kinase Nek2. Trf1 has a role in the regulation of telomerelength, but has also been implicated in cell cycle regulation. These interactions nowprovide a direct link between telomere length regulation and the control of mitoticprogression." @default.
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- W2085283608 date "2004-10-28" @default.
- W2085283608 modified "2023-10-17" @default.
- W2085283608 title "The Telomere Repeat Binding Protein Trf1 Interacts with the Spindle Checkpoint Protein Mad1 and Nek2 Mitotic Kinase" @default.
- W2085283608 doi "https://doi.org/10.4161/cc.4.1.1351" @default.
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