FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085289350> ?p ?o ?g. }

• W2085289350 endingPage "487" @default.
• W2085289350 startingPage "487" @default.
• W2085289350 abstract "To assess the impact of intravenous (IV) antibiotic prophylaxis on the incidence of pancreatic infection and the mortality rate in severe acute pancreatitis.Restropective review of a cohort of 180 patients with severe acute pancreatitis.A tertiary referral center in Sacramento, Calif.The use of IV antibiotic prophylaxis evolved during 3 periods from no antibiotics in 50 patients (1982-1989), to nonprotocol use in 55 patients (1990-1992), to a 4-week course of imipenem-cilastatin sodium (1993-1996) given to 75 patients having Acute Physiology and Chronic Health Evaluation (APACHE) II scores greater than 6 and pancreatic necrosis (> 15% of the gland), peripancreatic necrosis, or peripancreatic collection.Pancreatic infection and mortality.Without antibiotic prophylaxis, the incidence of pancreatic infection was 76% (38/50). Intravenous antibiotic prophylaxis reduced the infection rate of 45% (25/55) (P = .03). The imipenem-cilastatin protocol further reduced the infection rate to 27% (20/75) (P = .04). The mortality rates showed only a decreasing trend, from 16% (1982-1989) to 7% (1990-1992) to 5% (1993-1996) (P = .11). Patients with sterile severe acute pancreatitis had a mortality rate of 2% (2/97); whereas 17% (14/83) of patients with infection succumbed to the disease. Patients developing infection within the first 4 weeks from the onset of illness had mortality rates ranging from 19% to 40%, compared with 0% to 8% for those who became infected after 4 weeks. No patient with pancreatic infection developing after 4 weeks died with the imipenem-cilastatin protocol.Intravenous antibiotic prophylaxis significantly reduced the infection rate in severe acute pancreatitis, with only a trend toward improved survival. A prospective, randomized, double-blind multicenter trial comparing the efficacy of different types and/or combinations of antibiotic prophylaxis in severe acute pancreatitis is indicated." @default.
• W2085289350 created "2016-06-24" @default.
• W2085289350 creator A5001179598 @default.
• W2085289350 creator A5019893842 @default.
• W2085289350 date "1997-05-01" @default.
• W2085289350 modified "2023-10-16" @default.
• W2085289350 title "The Role of Antibiotic Prophylaxis in Severe Acute Pancreatitis" @default.
• W2085289350 cites W114503210 @default.
• W2085289350 cites W1579565822 @default.
• W2085289350 cites W1917229050 @default.
• W2085289350 cites W1926714676 @default.
• W2085289350 cites W192911850 @default.
• W2085289350 cites W1965463928 @default.
• W2085289350 cites W1969983795 @default.
• W2085289350 cites W1976400660 @default.
• W2085289350 cites W1985045980 @default.
• W2085289350 cites W1991945933 @default.
• W2085289350 cites W2001819213 @default.
• W2085289350 cites W2022863479 @default.
• W2085289350 cites W2026936598 @default.
• W2085289350 cites W2040590190 @default.
• W2085289350 cites W2047911350 @default.
• W2085289350 cites W2064765612 @default.
• W2085289350 cites W2081886420 @default.
• W2085289350 cites W2088931574 @default.
• W2085289350 cites W2091995287 @default.
• W2085289350 cites W2094465311 @default.
• W2085289350 cites W2124462959 @default.
• W2085289350 cites W2130922249 @default.
• W2085289350 cites W2132479898 @default.
• W2085289350 cites W2139307681 @default.
• W2085289350 cites W2399450974 @default.
• W2085289350 cites W2400154149 @default.
• W2085289350 cites W2403772434 @default.
• W2085289350 cites W2443457715 @default.
• W2085289350 cites W66690378 @default.
• W2085289350 cites W1568246494 @default.
• W2085289350 doi "https://doi.org/10.1001/archsurg.1997.01430290033004" @default.
• W2085289350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9161390" @default.
• W2085289350 hasPublicationYear "1997" @default.
• W2085289350 type Work @default.
• W2085289350 sameAs 2085289350 @default.
• W2085289350 citedByCount "116" @default.
• W2085289350 countsByYear W20852893502012 @default.
• W2085289350 countsByYear W20852893502013 @default.
• W2085289350 countsByYear W20852893502014 @default.
• W2085289350 countsByYear W20852893502015 @default.
• W2085289350 countsByYear W20852893502016 @default.
• W2085289350 countsByYear W20852893502022 @default.
• W2085289350 crossrefType "journal-article" @default.
• W2085289350 hasAuthorship W2085289350A5001179598 @default.
• W2085289350 hasAuthorship W2085289350A5019893842 @default.
• W2085289350 hasConcept C120665830 @default.
• W2085289350 hasConcept C121332964 @default.
• W2085289350 hasConcept C126322002 @default.
• W2085289350 hasConcept C141071460 @default.
• W2085289350 hasConcept C179755657 @default.
• W2085289350 hasConcept C2775967933 @default.
• W2085289350 hasConcept C2776670229 @default.
• W2085289350 hasConcept C2777437143 @default.
• W2085289350 hasConcept C2778602436 @default.
• W2085289350 hasConcept C2779631663 @default.
• W2085289350 hasConcept C501593827 @default.
• W2085289350 hasConcept C61511704 @default.
• W2085289350 hasConcept C71924100 @default.
• W2085289350 hasConcept C86803240 @default.
• W2085289350 hasConcept C89423630 @default.
• W2085289350 hasConcept C90924648 @default.
• W2085289350 hasConcept C94665300 @default.
• W2085289350 hasConceptScore W2085289350C120665830 @default.
• W2085289350 hasConceptScore W2085289350C121332964 @default.
• W2085289350 hasConceptScore W2085289350C126322002 @default.
• W2085289350 hasConceptScore W2085289350C141071460 @default.
• W2085289350 hasConceptScore W2085289350C179755657 @default.
• W2085289350 hasConceptScore W2085289350C2775967933 @default.
• W2085289350 hasConceptScore W2085289350C2776670229 @default.
• W2085289350 hasConceptScore W2085289350C2777437143 @default.
• W2085289350 hasConceptScore W2085289350C2778602436 @default.
• W2085289350 hasConceptScore W2085289350C2779631663 @default.
• W2085289350 hasConceptScore W2085289350C501593827 @default.
• W2085289350 hasConceptScore W2085289350C61511704 @default.
• W2085289350 hasConceptScore W2085289350C71924100 @default.
• W2085289350 hasConceptScore W2085289350C86803240 @default.
• W2085289350 hasConceptScore W2085289350C89423630 @default.
• W2085289350 hasConceptScore W2085289350C90924648 @default.
• W2085289350 hasConceptScore W2085289350C94665300 @default.
• W2085289350 hasIssue "5" @default.
• W2085289350 hasLocation W20852893501 @default.
• W2085289350 hasLocation W20852893502 @default.
• W2085289350 hasOpenAccess W2085289350 @default.
• W2085289350 hasPrimaryLocation W20852893501 @default.
• W2085289350 hasRelatedWork W1591978428 @default.
• W2085289350 hasRelatedWork W1998245452 @default.
• W2085289350 hasRelatedWork W2008878688 @default.
• W2085289350 hasRelatedWork W2085289350 @default.
• W2085289350 hasRelatedWork W2317265982 @default.
• W2085289350 hasRelatedWork W2376970967 @default.
• W2085289350 hasRelatedWork W2403772434 @default.

• next