Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085291204> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2085291204 endingPage "125" @default.
- W2085291204 startingPage "122" @default.
- W2085291204 abstract "Adenoviral vectors have shown promise in a variety of preclinical vascular disease models. Intravascular infusion is one methodology to introduce the adenoviral vector into the affected area of the blood vessel. The biocompatibility of the infusion catheter with the adenoviral vector is key for successful local transfer. It has been recently suggested that catheter-based delivery of adenoviral vectors may result in the loss of vector infectivity. We demonstrate here a catheter capable of delivering adenoviral vectors without the loss of viral particle or infectious titers. First- (DeltaE1) and second- (DeltaE1/DeltaE4) generation adenoviral vectors were tested for their biocompatibility with the Crescendo microporous infusion catheter, which is designed for local infusion of therapeutic agents to human coronary or peripheral arteries. We found that incubation of either the DeltaE1 or the DeltaE1/DeltaE4 viral vectors for up to 30 min in the catheter at 37 degrees C did not result in a loss of viral particles or of viral infectivity. Here, we show that the Crescendo catheter is biocompatible with adenoviral vectors and suitable for vascular gene therapy." @default.
- W2085291204 created "2016-06-24" @default.
- W2085291204 creator A5001329658 @default.
- W2085291204 creator A5021769075 @default.
- W2085291204 creator A5030401356 @default.
- W2085291204 creator A5034991616 @default.
- W2085291204 creator A5077126186 @default.
- W2085291204 creator A5077410799 @default.
- W2085291204 creator A5089053645 @default.
- W2085291204 date "2001-01-01" @default.
- W2085291204 modified "2023-09-24" @default.
- W2085291204 title "Stability of Adenoviral Vectors Following Catheter Delivery" @default.
- W2085291204 cites W1993384245 @default.
- W2085291204 cites W2000352597 @default.
- W2085291204 cites W2038483072 @default.
- W2085291204 cites W2044527317 @default.
- W2085291204 cites W2066993893 @default.
- W2085291204 cites W2081280908 @default.
- W2085291204 cites W2092483727 @default.
- W2085291204 cites W2132019682 @default.
- W2085291204 cites W2320869084 @default.
- W2085291204 doi "https://doi.org/10.1006/mthe.2000.0237" @default.
- W2085291204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11162319" @default.
- W2085291204 hasPublicationYear "2001" @default.
- W2085291204 type Work @default.
- W2085291204 sameAs 2085291204 @default.
- W2085291204 citedByCount "8" @default.
- W2085291204 countsByYear W20852912042020 @default.
- W2085291204 crossrefType "journal-article" @default.
- W2085291204 hasAuthorship W2085291204A5001329658 @default.
- W2085291204 hasAuthorship W2085291204A5021769075 @default.
- W2085291204 hasAuthorship W2085291204A5030401356 @default.
- W2085291204 hasAuthorship W2085291204A5034991616 @default.
- W2085291204 hasAuthorship W2085291204A5077126186 @default.
- W2085291204 hasAuthorship W2085291204A5077410799 @default.
- W2085291204 hasAuthorship W2085291204A5089053645 @default.
- W2085291204 hasBestOaLocation W20852912041 @default.
- W2085291204 hasConcept C104317684 @default.
- W2085291204 hasConcept C106358424 @default.
- W2085291204 hasConcept C111599444 @default.
- W2085291204 hasConcept C135983454 @default.
- W2085291204 hasConcept C141071460 @default.
- W2085291204 hasConcept C159047783 @default.
- W2085291204 hasConcept C178790620 @default.
- W2085291204 hasConcept C185592680 @default.
- W2085291204 hasConcept C2522874641 @default.
- W2085291204 hasConcept C2777230088 @default.
- W2085291204 hasConcept C2781267111 @default.
- W2085291204 hasConcept C32470452 @default.
- W2085291204 hasConcept C35693153 @default.
- W2085291204 hasConcept C40767141 @default.
- W2085291204 hasConcept C55493867 @default.
- W2085291204 hasConcept C71924100 @default.
- W2085291204 hasConcept C86803240 @default.
- W2085291204 hasConcept C92087593 @default.
- W2085291204 hasConceptScore W2085291204C104317684 @default.
- W2085291204 hasConceptScore W2085291204C106358424 @default.
- W2085291204 hasConceptScore W2085291204C111599444 @default.
- W2085291204 hasConceptScore W2085291204C135983454 @default.
- W2085291204 hasConceptScore W2085291204C141071460 @default.
- W2085291204 hasConceptScore W2085291204C159047783 @default.
- W2085291204 hasConceptScore W2085291204C178790620 @default.
- W2085291204 hasConceptScore W2085291204C185592680 @default.
- W2085291204 hasConceptScore W2085291204C2522874641 @default.
- W2085291204 hasConceptScore W2085291204C2777230088 @default.
- W2085291204 hasConceptScore W2085291204C2781267111 @default.
- W2085291204 hasConceptScore W2085291204C32470452 @default.
- W2085291204 hasConceptScore W2085291204C35693153 @default.
- W2085291204 hasConceptScore W2085291204C40767141 @default.
- W2085291204 hasConceptScore W2085291204C55493867 @default.
- W2085291204 hasConceptScore W2085291204C71924100 @default.
- W2085291204 hasConceptScore W2085291204C86803240 @default.
- W2085291204 hasConceptScore W2085291204C92087593 @default.
- W2085291204 hasIssue "1" @default.
- W2085291204 hasLocation W20852912041 @default.
- W2085291204 hasLocation W20852912042 @default.
- W2085291204 hasOpenAccess W2085291204 @default.
- W2085291204 hasPrimaryLocation W20852912041 @default.
- W2085291204 hasRelatedWork W1970638821 @default.
- W2085291204 hasRelatedWork W1996746326 @default.
- W2085291204 hasRelatedWork W2146518428 @default.
- W2085291204 hasRelatedWork W2163708786 @default.
- W2085291204 hasRelatedWork W2408762070 @default.
- W2085291204 hasRelatedWork W2530679069 @default.
- W2085291204 hasRelatedWork W289467534 @default.
- W2085291204 hasRelatedWork W4293568610 @default.
- W2085291204 hasRelatedWork W43273318 @default.
- W2085291204 hasRelatedWork W64058586 @default.
- W2085291204 hasVolume "3" @default.
- W2085291204 isParatext "false" @default.
- W2085291204 isRetracted "false" @default.
- W2085291204 magId "2085291204" @default.
- W2085291204 workType "article" @default.