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• W2085303242 abstract "We discuss variance reduced simulations for an individual-based model of chemotaxis of bacteria with internal dynamics. The variance reduction is achieved via a coupling of this model with a simpler process in which the internal dynamics has been replaced by a direct gradient sensing of the chemoattractants concentrations. In the companion paper [Individual-based models for bacterial chemotaxis in the diffusion limit (to appear in Math. Models Methods Appl. Sci., DOI: 10.1142/S0218202513500243)], we have rigorously shown, using a pathwise probabilistic technique, that both processes converge towards the same advection–diffusion process in the diffusive asymptotics. In this work, a direct coupling is achieved between paths of individual bacteria simulated by both models, by using the same sets of random numbers in both simulations. This coupling is used to construct a hybrid scheme with reduced variance. We first compute a deterministic solution of the kinetic density description of the direct gradient sensing model; the deviations due to the presence of internal dynamics are then evaluated via the coupled individual-based simulations. We show that the resulting variance reduction is asymptotic, in the sense that, in the diffusive asymptotics, the difference between the two processes has a variance which vanishes according to the small parameter." @default.
• W2085303242 created "2016-06-24" @default.
• W2085303242 creator A5007947181 @default.
• W2085303242 creator A5033331209 @default.
• W2085303242 date "2013-08-18" @default.
• W2085303242 modified "2023-10-10" @default.
• W2085303242 title "SIMULATING INDIVIDUAL-BASED MODELS OF BACTERIAL CHEMOTAXIS WITH ASYMPTOTIC VARIANCE REDUCTION" @default.
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• W2085303242 doi "https://doi.org/10.1142/s0218202513500292" @default.
• W2085303242 hasPublicationYear "2013" @default.
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