Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085325053> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2085325053 endingPage "58" @default.
- W2085325053 startingPage "51" @default.
- W2085325053 abstract "The ability of polymeric microspheres fabricated from Carbopol, polycarbophil, chitosan or Gantrez to retain a model hydrophilic drug (sodium fluorescein) was evaluated in situ, using a dynamic test system and image analysis. This technique used oesophageal tissues and simulated the physiological conditions within the oral cavity in terms of temperature, humidity and saliva flow. The point of sample application was observed over a 2 h period by means of a digital camera. No significant differences in fluorescein colour intensity was obtained for the Gantrez and chitosan particles over 100 min, indicate that these two polymers provide the possibility of prolonged action. Carbopol and polycarbophil particles became rapidly swollen and released the sodium fluorescein completely within 20 min. It was concluded that the test system allowed the evaluation of the in situ behaviour of test particles, in terms of their ability to retain a water-soluble, coloured marker in ‘dynamic’ test conditions, and that chitosan and Gantrez were promising candidates for the production of mucoadhesive, sustained-release microspheres for water-soluble materials." @default.
- W2085325053 created "2016-06-24" @default.
- W2085325053 creator A5004755318 @default.
- W2085325053 creator A5007223780 @default.
- W2085325053 creator A5032578813 @default.
- W2085325053 creator A5061902473 @default.
- W2085325053 creator A5071151580 @default.
- W2085325053 date "2004-05-01" @default.
- W2085325053 modified "2023-10-17" @default.
- W2085325053 title "In situ evaluation of drug-loaded microspheres on a mucosal surface under dynamic test conditions" @default.
- W2085325053 cites W1966353013 @default.
- W2085325053 cites W1979358687 @default.
- W2085325053 cites W1982103111 @default.
- W2085325053 cites W1983944067 @default.
- W2085325053 cites W2014474852 @default.
- W2085325053 cites W2016137484 @default.
- W2085325053 cites W2066312718 @default.
- W2085325053 cites W2085851466 @default.
- W2085325053 cites W2086940605 @default.
- W2085325053 cites W2091080223 @default.
- W2085325053 cites W2118156762 @default.
- W2085325053 cites W2166212375 @default.
- W2085325053 doi "https://doi.org/10.1016/j.ijpharm.2004.02.020" @default.
- W2085325053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15113613" @default.
- W2085325053 hasPublicationYear "2004" @default.
- W2085325053 type Work @default.
- W2085325053 sameAs 2085325053 @default.
- W2085325053 citedByCount "29" @default.
- W2085325053 countsByYear W20853250532012 @default.
- W2085325053 countsByYear W20853250532013 @default.
- W2085325053 countsByYear W20853250532014 @default.
- W2085325053 countsByYear W20853250532015 @default.
- W2085325053 countsByYear W20853250532016 @default.
- W2085325053 countsByYear W20853250532017 @default.
- W2085325053 countsByYear W20853250532018 @default.
- W2085325053 crossrefType "journal-article" @default.
- W2085325053 hasAuthorship W2085325053A5004755318 @default.
- W2085325053 hasAuthorship W2085325053A5007223780 @default.
- W2085325053 hasAuthorship W2085325053A5032578813 @default.
- W2085325053 hasAuthorship W2085325053A5061902473 @default.
- W2085325053 hasAuthorship W2085325053A5071151580 @default.
- W2085325053 hasConcept C120665830 @default.
- W2085325053 hasConcept C121332964 @default.
- W2085325053 hasConcept C127413603 @default.
- W2085325053 hasConcept C136229726 @default.
- W2085325053 hasConcept C178790620 @default.
- W2085325053 hasConcept C185592680 @default.
- W2085325053 hasConcept C189942447 @default.
- W2085325053 hasConcept C192562407 @default.
- W2085325053 hasConcept C2777822432 @default.
- W2085325053 hasConcept C2778015030 @default.
- W2085325053 hasConcept C2779732960 @default.
- W2085325053 hasConcept C2910948884 @default.
- W2085325053 hasConcept C42360764 @default.
- W2085325053 hasConcept C43617362 @default.
- W2085325053 hasConcept C71924100 @default.
- W2085325053 hasConcept C77281830 @default.
- W2085325053 hasConcept C91881484 @default.
- W2085325053 hasConceptScore W2085325053C120665830 @default.
- W2085325053 hasConceptScore W2085325053C121332964 @default.
- W2085325053 hasConceptScore W2085325053C127413603 @default.
- W2085325053 hasConceptScore W2085325053C136229726 @default.
- W2085325053 hasConceptScore W2085325053C178790620 @default.
- W2085325053 hasConceptScore W2085325053C185592680 @default.
- W2085325053 hasConceptScore W2085325053C189942447 @default.
- W2085325053 hasConceptScore W2085325053C192562407 @default.
- W2085325053 hasConceptScore W2085325053C2777822432 @default.
- W2085325053 hasConceptScore W2085325053C2778015030 @default.
- W2085325053 hasConceptScore W2085325053C2779732960 @default.
- W2085325053 hasConceptScore W2085325053C2910948884 @default.
- W2085325053 hasConceptScore W2085325053C42360764 @default.
- W2085325053 hasConceptScore W2085325053C43617362 @default.
- W2085325053 hasConceptScore W2085325053C71924100 @default.
- W2085325053 hasConceptScore W2085325053C77281830 @default.
- W2085325053 hasConceptScore W2085325053C91881484 @default.
- W2085325053 hasIssue "1-2" @default.
- W2085325053 hasLocation W20853250531 @default.
- W2085325053 hasLocation W20853250532 @default.
- W2085325053 hasOpenAccess W2085325053 @default.
- W2085325053 hasPrimaryLocation W20853250531 @default.
- W2085325053 hasRelatedWork W2002134771 @default.
- W2085325053 hasRelatedWork W2098507039 @default.
- W2085325053 hasRelatedWork W2370996010 @default.
- W2085325053 hasRelatedWork W2464606258 @default.
- W2085325053 hasRelatedWork W2871482238 @default.
- W2085325053 hasRelatedWork W3214692145 @default.
- W2085325053 hasRelatedWork W4248735482 @default.
- W2085325053 hasRelatedWork W4386007840 @default.
- W2085325053 hasRelatedWork W57316225 @default.
- W2085325053 hasRelatedWork W2488038693 @default.
- W2085325053 hasVolume "276" @default.
- W2085325053 isParatext "false" @default.
- W2085325053 isRetracted "false" @default.
- W2085325053 magId "2085325053" @default.
- W2085325053 workType "article" @default.