FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085344098> ?p ?o ?g. }

• W2085344098 abstract "Since the late 1970s, the possible increased risk of ovarian cancer in women taking fertility drugs has received much public attention and raised patient anxiety. Three epidemiological studies published between 1992 and 1996 reported that fertility drugs increased risks of ovarian cancer. Although a large number of subsequent epidemiological studies found no strong association between use of fertility drugs and risk of ovarian cancer, most of these studies had methodologic problems. This population-based cohort study assessed the possible association between use of fertility drugs and overall risk of ovarian cancer among 54,362 Danish women who attended infertility clinics between 1963 and 1998. Data on the reproductive history for all infertile women with ovarian cancer in the cohort after enrollment and for those in the subcohort was obtained from the Danish National Birth Registry, the Danish Cancer Registry, and the Danish Registry of Pathology. The median year for enrollment was 1989. The median age at the initial evaluation for infertility was 30 years, and the median age at the end of follow-up was 47 years. A total of 156 women with invasive epithelial ovarian cancer (cases) were included in the analysis. A subcohort of 1241 women who were randomly selected during follow-up in 2006 served as the comparison group. The median follow-up was 16 years and 25% of the cases were followed for more than 23 years. The overall risk of ovarian cancer was examined in 4 groups of fertility drugs (gonadotropins, clomiphene, human chorionic gonadotropin, and gonadotropin releasing hormone). Cox regression analysis was used to adjust risk ratios for potential confounding factors. The overall risk of ovarian cancer was not significantly affected by use of gonadotropins (adjusted rate ratio [aRR], 0.83; 95% confidence interval [CI], 0.50―1.37), clomiphene (aRR, 1.14; 95% CI, 0.79―1.64), human chorionic gonadotropin (aRR, 0.89; 95% CI, 0.62―1.29), or gonadotropin releasing hormone (aRR, 0.80; 95% CI, 0.42―1.51). For all 4 groups of fertility drugs, the risk of ovarian cancer was not affected by the number of cycles of use, length of follow-up since first use of drug, or parity. These findings are consistent with those of most previous epidemiological studies and provide additional evidence for the absence of a strong association between use of fertility drugs and overall risk of ovarian cancer." @default.
• W2085344098 created "2016-06-24" @default.
• W2085344098 creator A5008310706 @default.
• W2085344098 creator A5018696972 @default.
• W2085344098 creator A5035002018 @default.
• W2085344098 creator A5037046832 @default.
• W2085344098 date "2009-06-01" @default.
• W2085344098 modified "2023-09-28" @default.
• W2085344098 title "Use of Fertility Drugs and Risk of Ovarian Cancer: Danish Population Based Cohort Study" @default.
• W2085344098 doi "https://doi.org/10.1097/01.ogx.0000349781.28386.c8" @default.
• W2085344098 hasPublicationYear "2009" @default.
• W2085344098 type Work @default.
• W2085344098 sameAs 2085344098 @default.
• W2085344098 citedByCount "1" @default.
• W2085344098 countsByYear W20853440982013 @default.
• W2085344098 crossrefType "journal-article" @default.
• W2085344098 hasAuthorship W2085344098A5008310706 @default.
• W2085344098 hasAuthorship W2085344098A5018696972 @default.
• W2085344098 hasAuthorship W2085344098A5035002018 @default.
• W2085344098 hasAuthorship W2085344098A5037046832 @default.
• W2085344098 hasBestOaLocation W20853440982 @default.
• W2085344098 hasConcept C107130276 @default.
• W2085344098 hasConcept C121608353 @default.
• W2085344098 hasConcept C126322002 @default.
• W2085344098 hasConcept C131872663 @default.
• W2085344098 hasConcept C138885662 @default.
• W2085344098 hasConcept C164622146 @default.
• W2085344098 hasConcept C201903717 @default.
• W2085344098 hasConcept C2777688143 @default.
• W2085344098 hasConcept C2778527826 @default.
• W2085344098 hasConcept C2779234561 @default.
• W2085344098 hasConcept C2780427987 @default.
• W2085344098 hasConcept C2908647359 @default.
• W2085344098 hasConcept C29456083 @default.
• W2085344098 hasConcept C41895202 @default.
• W2085344098 hasConcept C518429986 @default.
• W2085344098 hasConcept C54355233 @default.
• W2085344098 hasConcept C71924100 @default.
• W2085344098 hasConcept C72563966 @default.
• W2085344098 hasConcept C86803240 @default.
• W2085344098 hasConcept C99454951 @default.
• W2085344098 hasConceptScore W2085344098C107130276 @default.
• W2085344098 hasConceptScore W2085344098C121608353 @default.
• W2085344098 hasConceptScore W2085344098C126322002 @default.
• W2085344098 hasConceptScore W2085344098C131872663 @default.
• W2085344098 hasConceptScore W2085344098C138885662 @default.
• W2085344098 hasConceptScore W2085344098C164622146 @default.
• W2085344098 hasConceptScore W2085344098C201903717 @default.
• W2085344098 hasConceptScore W2085344098C2777688143 @default.
• W2085344098 hasConceptScore W2085344098C2778527826 @default.
• W2085344098 hasConceptScore W2085344098C2779234561 @default.
• W2085344098 hasConceptScore W2085344098C2780427987 @default.
• W2085344098 hasConceptScore W2085344098C2908647359 @default.
• W2085344098 hasConceptScore W2085344098C29456083 @default.
• W2085344098 hasConceptScore W2085344098C41895202 @default.
• W2085344098 hasConceptScore W2085344098C518429986 @default.
• W2085344098 hasConceptScore W2085344098C54355233 @default.
• W2085344098 hasConceptScore W2085344098C71924100 @default.
• W2085344098 hasConceptScore W2085344098C72563966 @default.
• W2085344098 hasConceptScore W2085344098C86803240 @default.
• W2085344098 hasConceptScore W2085344098C99454951 @default.
• W2085344098 hasLocation W20853440981 @default.
• W2085344098 hasLocation W20853440982 @default.
• W2085344098 hasOpenAccess W2085344098 @default.
• W2085344098 hasPrimaryLocation W20853440981 @default.
• W2085344098 hasRelatedWork W184591302 @default.
• W2085344098 hasRelatedWork W1973901345 @default.
• W2085344098 hasRelatedWork W1995582002 @default.
• W2085344098 hasRelatedWork W2056833186 @default.
• W2085344098 hasRelatedWork W2109879670 @default.
• W2085344098 hasRelatedWork W2120039304 @default.
• W2085344098 hasRelatedWork W2129546497 @default.
• W2085344098 hasRelatedWork W2134589371 @default.
• W2085344098 hasRelatedWork W2152092767 @default.
• W2085344098 hasRelatedWork W2156794509 @default.
• W2085344098 hasRelatedWork W2165239475 @default.
• W2085344098 hasRelatedWork W2313836530 @default.
• W2085344098 hasRelatedWork W2562327903 @default.
• W2085344098 hasRelatedWork W2573520885 @default.
• W2085344098 hasRelatedWork W2622819742 @default.
• W2085344098 hasRelatedWork W2974905792 @default.
• W2085344098 hasRelatedWork W2979677116 @default.
• W2085344098 hasRelatedWork W3120824197 @default.
• W2085344098 hasRelatedWork W3136186080 @default.
• W2085344098 hasRelatedWork W71961220 @default.
• W2085344098 isParatext "false" @default.
• W2085344098 isRetracted "false" @default.
• W2085344098 magId "2085344098" @default.
• W2085344098 workType "article" @default.