Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085347178> ?p ?o ?g. }
- W2085347178 endingPage "391" @default.
- W2085347178 startingPage "381" @default.
- W2085347178 abstract "The gene encoding a 23 kilodalton protein antigen has been cloned from Mycobacterium tuberculosis by screening of a recombinant DNA library with monoclonal antibodies. The product of the gene has been identified as the superoxide dismutase (SOD) of M. tuberculosis on the basis of sequence comparison and by expression of the recombinant protein in a functionally active form. The derived amino acid sequence of M. tuberculosis SOD reveals a close similarity to manganese-containing SODs from other organisms, in spite of the fact that previous studies using the purified enzyme have identified iron as the preferred metal ion ligand. SOD is present in the extracellular fluid of logarithmic-phase cultures of M. tuberculosis, but the structural gene is not preceded by a signal peptide sequence. Insertion of the M. tuberculosis SOD gene into a novel shuttle vector demonstrated the presence of a promoter which functions efficiently in mycobacteria but is ineffective in Escherichia coli" @default.
- W2085347178 created "2016-06-24" @default.
- W2085347178 creator A5001202729 @default.
- W2085347178 creator A5012079560 @default.
- W2085347178 creator A5036358780 @default.
- W2085347178 creator A5040301287 @default.
- W2085347178 creator A5044976782 @default.
- W2085347178 date "1991-02-01" @default.
- W2085347178 modified "2023-10-14" @default.
- W2085347178 title "Genetic analysis of superoxide dismutase, the 23 kilodalton antigen of Mycobacterium tuberculosis" @default.
- W2085347178 cites W1509038183 @default.
- W2085347178 cites W1526731452 @default.
- W2085347178 cites W1552890707 @default.
- W2085347178 cites W1561715970 @default.
- W2085347178 cites W1598449453 @default.
- W2085347178 cites W1601687245 @default.
- W2085347178 cites W1822247677 @default.
- W2085347178 cites W1876858754 @default.
- W2085347178 cites W1891988303 @default.
- W2085347178 cites W1906303910 @default.
- W2085347178 cites W1912825022 @default.
- W2085347178 cites W1914841321 @default.
- W2085347178 cites W1929862656 @default.
- W2085347178 cites W1972186001 @default.
- W2085347178 cites W1984940664 @default.
- W2085347178 cites W1987532832 @default.
- W2085347178 cites W1995481544 @default.
- W2085347178 cites W2004653288 @default.
- W2085347178 cites W2009136105 @default.
- W2085347178 cites W2021753888 @default.
- W2085347178 cites W2023871230 @default.
- W2085347178 cites W2028622989 @default.
- W2085347178 cites W2033827849 @default.
- W2085347178 cites W2037014228 @default.
- W2085347178 cites W2045944193 @default.
- W2085347178 cites W2056168344 @default.
- W2085347178 cites W2066352920 @default.
- W2085347178 cites W2068446924 @default.
- W2085347178 cites W2069948551 @default.
- W2085347178 cites W2086940218 @default.
- W2085347178 cites W2087587775 @default.
- W2085347178 cites W2097306976 @default.
- W2085347178 cites W2100837269 @default.
- W2085347178 cites W2101108802 @default.
- W2085347178 cites W2101422765 @default.
- W2085347178 cites W2106383495 @default.
- W2085347178 cites W2112486357 @default.
- W2085347178 cites W2128378823 @default.
- W2085347178 cites W2138091468 @default.
- W2085347178 cites W2154213475 @default.
- W2085347178 cites W2161524167 @default.
- W2085347178 cites W2161680446 @default.
- W2085347178 cites W2278413978 @default.
- W2085347178 cites W4230238808 @default.
- W2085347178 cites W4231524173 @default.
- W2085347178 cites W4231923287 @default.
- W2085347178 doi "https://doi.org/10.1111/j.1365-2958.1991.tb02120.x" @default.
- W2085347178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1904126" @default.
- W2085347178 hasPublicationYear "1991" @default.
- W2085347178 type Work @default.
- W2085347178 sameAs 2085347178 @default.
- W2085347178 citedByCount "176" @default.
- W2085347178 countsByYear W20853471782012 @default.
- W2085347178 countsByYear W20853471782013 @default.
- W2085347178 countsByYear W20853471782014 @default.
- W2085347178 countsByYear W20853471782015 @default.
- W2085347178 countsByYear W20853471782016 @default.
- W2085347178 countsByYear W20853471782017 @default.
- W2085347178 countsByYear W20853471782018 @default.
- W2085347178 countsByYear W20853471782019 @default.
- W2085347178 countsByYear W20853471782020 @default.
- W2085347178 countsByYear W20853471782021 @default.
- W2085347178 countsByYear W20853471782022 @default.
- W2085347178 crossrefType "journal-article" @default.
- W2085347178 hasAuthorship W2085347178A5001202729 @default.
- W2085347178 hasAuthorship W2085347178A5012079560 @default.
- W2085347178 hasAuthorship W2085347178A5036358780 @default.
- W2085347178 hasAuthorship W2085347178A5040301287 @default.
- W2085347178 hasAuthorship W2085347178A5044976782 @default.
- W2085347178 hasConcept C104317684 @default.
- W2085347178 hasConcept C10858879 @default.
- W2085347178 hasConcept C142724271 @default.
- W2085347178 hasConcept C145640855 @default.
- W2085347178 hasConcept C147483822 @default.
- W2085347178 hasConcept C153911025 @default.
- W2085347178 hasConcept C167625842 @default.
- W2085347178 hasConcept C181199279 @default.
- W2085347178 hasConcept C195616568 @default.
- W2085347178 hasConcept C2775838275 @default.
- W2085347178 hasConcept C2777975735 @default.
- W2085347178 hasConcept C2781069245 @default.
- W2085347178 hasConcept C40767141 @default.
- W2085347178 hasConcept C54355233 @default.
- W2085347178 hasConcept C547475151 @default.
- W2085347178 hasConcept C55493867 @default.
- W2085347178 hasConcept C71924100 @default.
- W2085347178 hasConcept C86803240 @default.
- W2085347178 hasConcept C92087593 @default.