FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085361149> ?p ?o ?g. }

• W2085361149 endingPage "543" @default.
• W2085361149 startingPage "537" @default.
• W2085361149 abstract "This study evaluates diagnostic markers to predict titanium implant failure. Retrospectively, implant outcome was scored in 109 subjects who had undergone titanium implant surgery, IL1A −889 C/T (rs1800587), IL1B +3954 C/T (rs1143634), IL1RN +2018 T/C (rs419598) and TNFA −308 G/A (rs1800629) genotyping, in vitro IL-1β/TNF-α release assays and lymphocyte transformation tests during treatment. TNF-α and IL-1β release on titanium stimulation were significantly higher among patients with implant loss (TNF-α: 256.89 pg/ml vs. 81.4 pg/ml; p < 0.0001; IL-1β: 159.96 pg/ml vs. 54.01 pg/ml; p < 0.0001). The minor alleles of the studied polymorphisms showed increased prevalence in the implant failure group (IL1A: 61% vs. 42.6% in controls, IL1B: 53.7% vs. 39.7% in controls, TNFA: 46.3% vs. 30.9% in controls, IL1RN: 58.5% vs. 52.9% in controls). Increasing numbers of risk genotypes of the studied polymorphisms were associated with an increasing risk of implant loss, suggesting an additive effect. Multiple logistic regression analysis showed positive IL-1β/TNF-α release assay scores (p < 0.0001, OR = 12.01) and number of risk genotypes (p < 0.046, OR = 1.57–6.01) being significantly and independently associated with titanium implant failure. IL-1/IL1RN/TNFA genotyping and cytokine release assay scores provide prognostic markers for titanium implant outcome and may present new tools for individual risk assessment." @default.
• W2085361149 created "2016-06-24" @default.
• W2085361149 creator A5021558077 @default.
• W2085361149 creator A5069995867 @default.
• W2085361149 creator A5078288864 @default.
• W2085361149 date "2013-04-01" @default.
• W2085361149 modified "2023-09-27" @default.
• W2085361149 title "Genetic and immunological markers predict titanium implant failure: a retrospective study" @default.
• W2085361149 cites W1525531948 @default.
• W2085361149 cites W1966370706 @default.
• W2085361149 cites W1988336043 @default.
• W2085361149 cites W1996567877 @default.
• W2085361149 cites W2004639926 @default.
• W2085361149 cites W2013203343 @default.
• W2085361149 cites W2014440426 @default.
• W2085361149 cites W2017494903 @default.
• W2085361149 cites W2018932525 @default.
• W2085361149 cites W2020399248 @default.
• W2085361149 cites W2023751561 @default.
• W2085361149 cites W2031467894 @default.
• W2085361149 cites W2046675807 @default.
• W2085361149 cites W2052396235 @default.
• W2085361149 cites W2059492476 @default.
• W2085361149 cites W2061542205 @default.
• W2085361149 cites W2084589943 @default.
• W2085361149 cites W2086389459 @default.
• W2085361149 cites W2088658330 @default.
• W2085361149 cites W2089328582 @default.
• W2085361149 cites W2089558505 @default.
• W2085361149 cites W2119569059 @default.
• W2085361149 cites W2138546131 @default.
• W2085361149 cites W2151005356 @default.
• W2085361149 cites W2155549872 @default.
• W2085361149 cites W2166688593 @default.
• W2085361149 cites W2171322382 @default.
• W2085361149 cites W2486683298 @default.
• W2085361149 cites W2791537927 @default.
• W2085361149 cites W2941595795 @default.
• W2085361149 cites W4241833560 @default.
• W2085361149 doi "https://doi.org/10.1016/j.ijom.2012.07.018" @default.
• W2085361149 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22925444" @default.
• W2085361149 hasPublicationYear "2013" @default.
• W2085361149 type Work @default.
• W2085361149 sameAs 2085361149 @default.
• W2085361149 citedByCount "77" @default.
• W2085361149 countsByYear W20853611492013 @default.
• W2085361149 countsByYear W20853611492014 @default.
• W2085361149 countsByYear W20853611492015 @default.
• W2085361149 countsByYear W20853611492016 @default.
• W2085361149 countsByYear W20853611492017 @default.
• W2085361149 countsByYear W20853611492018 @default.
• W2085361149 countsByYear W20853611492019 @default.
• W2085361149 countsByYear W20853611492020 @default.
• W2085361149 countsByYear W20853611492021 @default.
• W2085361149 countsByYear W20853611492022 @default.
• W2085361149 countsByYear W20853611492023 @default.
• W2085361149 crossrefType "journal-article" @default.
• W2085361149 hasAuthorship W2085361149A5021558077 @default.
• W2085361149 hasAuthorship W2085361149A5069995867 @default.
• W2085361149 hasAuthorship W2085361149A5078288864 @default.
• W2085361149 hasConcept C104317684 @default.
• W2085361149 hasConcept C126322002 @default.
• W2085361149 hasConcept C135763542 @default.
• W2085361149 hasConcept C141071460 @default.
• W2085361149 hasConcept C17991360 @default.
• W2085361149 hasConcept C2778614594 @default.
• W2085361149 hasConcept C2781411149 @default.
• W2085361149 hasConcept C31467283 @default.
• W2085361149 hasConcept C55493867 @default.
• W2085361149 hasConcept C71924100 @default.
• W2085361149 hasConcept C86803240 @default.
• W2085361149 hasConcept C90924648 @default.
• W2085361149 hasConceptScore W2085361149C104317684 @default.
• W2085361149 hasConceptScore W2085361149C126322002 @default.
• W2085361149 hasConceptScore W2085361149C135763542 @default.
• W2085361149 hasConceptScore W2085361149C141071460 @default.
• W2085361149 hasConceptScore W2085361149C17991360 @default.
• W2085361149 hasConceptScore W2085361149C2778614594 @default.
• W2085361149 hasConceptScore W2085361149C2781411149 @default.
• W2085361149 hasConceptScore W2085361149C31467283 @default.
• W2085361149 hasConceptScore W2085361149C55493867 @default.
• W2085361149 hasConceptScore W2085361149C71924100 @default.
• W2085361149 hasConceptScore W2085361149C86803240 @default.
• W2085361149 hasConceptScore W2085361149C90924648 @default.
• W2085361149 hasIssue "4" @default.
• W2085361149 hasLocation W20853611491 @default.
• W2085361149 hasLocation W20853611492 @default.
• W2085361149 hasOpenAccess W2085361149 @default.
• W2085361149 hasPrimaryLocation W20853611491 @default.
• W2085361149 hasRelatedWork W2003938723 @default.
• W2085361149 hasRelatedWork W2047967234 @default.
• W2085361149 hasRelatedWork W2118496982 @default.
• W2085361149 hasRelatedWork W2349105149 @default.
• W2085361149 hasRelatedWork W2377518790 @default.
• W2085361149 hasRelatedWork W2394359576 @default.
• W2085361149 hasRelatedWork W2439875401 @default.
• W2085361149 hasRelatedWork W2463477745 @default.
• W2085361149 hasRelatedWork W3006519870 @default.

• next