FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085365590> ?p ?o ?g. }

• W2085365590 abstract "The motion of small cargo particles on microtubules by means of motor proteins in disordered microtubule networks is investigated theoretically using both analytical tools and computer simulations. Different network topologies in two and three dimensions are considered, one of which has been recently studied experimentally by Salman et al. [Biophys. J. 89, 2134 (2005)]. A generalization of the random velocity model is used to derive the mean-square displacement of the cargo particle. We find that all cases belong to the class of anomalous superdiffusion, which is sensitive mainly to the dimensionality of the network and only marginally to its topology. Yet in three dimensions the motion is very close to simple diffusion, with sublogarithmic corrections that depend on the network topology. When details of the thermal diffusion in the bulk solution are included, no significant change to the asymptotic time behavior is found. However, a small asymmetry in the mean microtubule polarity affects the corresponding long-time behavior. We also study a three-dimensional model of the microtubule network in living animal cells. Three first-passage-time problems of intracellular transport are simulated and analyzed for different motor processivities: (i) cargo that originates near the nucleus and has to reach the membrane, (ii) cargo that originates from the membrane and has to reach the nucleus, and (iii) cargo that leaves the nucleus and has to reach a specific target in the cytoplasm. We conclude that while a higher motor processivity increases the transport efficiency in cases (i) and (ii), in case (iii) it has the opposite effect. We conjecture that the balance between the different network tasks, as manifested in cases (i) and (ii) versus case (iii), may be the reason for the evolutionary choice of a finite motor processivity." @default.
• W2085365590 created "2016-06-24" @default.
• W2085365590 creator A5021555323 @default.
• W2085365590 creator A5028557315 @default.
• W2085365590 creator A5039241455 @default.
• W2085365590 creator A5062963261 @default.
• W2085365590 creator A5070535020 @default.
• W2085365590 date "2008-11-13" @default.
• W2085365590 modified "2023-10-17" @default.
• W2085365590 title "Active transport on disordered microtubule networks: The generalized random velocity model" @default.
• W2085365590 cites W1968921863 @default.
• W2085365590 cites W1975928024 @default.
• W2085365590 cites W1978532747 @default.
• W2085365590 cites W1984936312 @default.
• W2085365590 cites W1985151525 @default.
• W2085365590 cites W1988678641 @default.
• W2085365590 cites W1997389610 @default.
• W2085365590 cites W2000217017 @default.
• W2085365590 cites W2013765436 @default.
• W2085365590 cites W2027758338 @default.
• W2085365590 cites W2039337124 @default.
• W2085365590 cites W2046283605 @default.
• W2085365590 cites W2052330857 @default.
• W2085365590 cites W2061272721 @default.
• W2085365590 cites W2063843701 @default.
• W2085365590 cites W2073273867 @default.
• W2085365590 cites W2084058002 @default.
• W2085365590 cites W2087954629 @default.
• W2085365590 cites W2089452414 @default.
• W2085365590 cites W2095051959 @default.
• W2085365590 cites W2102144507 @default.
• W2085365590 cites W2136304736 @default.
• W2085365590 cites W2144679032 @default.
• W2085365590 cites W2145479669 @default.
• W2085365590 cites W2146654319 @default.
• W2085365590 cites W2151274733 @default.
• W2085365590 cites W2152453992 @default.
• W2085365590 cites W2152516404 @default.
• W2085365590 cites W2157256220 @default.
• W2085365590 cites W4255053085 @default.
• W2085365590 doi "https://doi.org/10.1103/physreve.78.051912" @default.
• W2085365590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19113160" @default.
• W2085365590 hasPublicationYear "2008" @default.
• W2085365590 type Work @default.
• W2085365590 sameAs 2085365590 @default.
• W2085365590 citedByCount "39" @default.
• W2085365590 countsByYear W20853655902012 @default.
• W2085365590 countsByYear W20853655902013 @default.
• W2085365590 countsByYear W20853655902014 @default.
• W2085365590 countsByYear W20853655902015 @default.
• W2085365590 countsByYear W20853655902016 @default.
• W2085365590 countsByYear W20853655902017 @default.
• W2085365590 countsByYear W20853655902018 @default.
• W2085365590 countsByYear W20853655902019 @default.
• W2085365590 countsByYear W20853655902020 @default.
• W2085365590 countsByYear W20853655902022 @default.
• W2085365590 countsByYear W20853655902023 @default.
• W2085365590 crossrefType "journal-article" @default.
• W2085365590 hasAuthorship W2085365590A5021555323 @default.
• W2085365590 hasAuthorship W2085365590A5028557315 @default.
• W2085365590 hasAuthorship W2085365590A5039241455 @default.
• W2085365590 hasAuthorship W2085365590A5062963261 @default.
• W2085365590 hasAuthorship W2085365590A5070535020 @default.
• W2085365590 hasConcept C105795698 @default.
• W2085365590 hasConcept C111919701 @default.
• W2085365590 hasConcept C114614502 @default.
• W2085365590 hasConcept C121194460 @default.
• W2085365590 hasConcept C121332964 @default.
• W2085365590 hasConcept C121864883 @default.
• W2085365590 hasConcept C12554922 @default.
• W2085365590 hasConcept C160408235 @default.
• W2085365590 hasConcept C164602753 @default.
• W2085365590 hasConcept C184720557 @default.
• W2085365590 hasConcept C187128312 @default.
• W2085365590 hasConcept C199845137 @default.
• W2085365590 hasConcept C20418707 @default.
• W2085365590 hasConcept C3017618536 @default.
• W2085365590 hasConcept C33923547 @default.
• W2085365590 hasConcept C41008148 @default.
• W2085365590 hasConcept C56739046 @default.
• W2085365590 hasConcept C59593255 @default.
• W2085365590 hasConcept C62520636 @default.
• W2085365590 hasConcept C69357855 @default.
• W2085365590 hasConcept C86803240 @default.
• W2085365590 hasConcept C95444343 @default.
• W2085365590 hasConceptScore W2085365590C105795698 @default.
• W2085365590 hasConceptScore W2085365590C111919701 @default.
• W2085365590 hasConceptScore W2085365590C114614502 @default.
• W2085365590 hasConceptScore W2085365590C121194460 @default.
• W2085365590 hasConceptScore W2085365590C121332964 @default.
• W2085365590 hasConceptScore W2085365590C121864883 @default.
• W2085365590 hasConceptScore W2085365590C12554922 @default.
• W2085365590 hasConceptScore W2085365590C160408235 @default.
• W2085365590 hasConceptScore W2085365590C164602753 @default.
• W2085365590 hasConceptScore W2085365590C184720557 @default.
• W2085365590 hasConceptScore W2085365590C187128312 @default.
• W2085365590 hasConceptScore W2085365590C199845137 @default.
• W2085365590 hasConceptScore W2085365590C20418707 @default.
• W2085365590 hasConceptScore W2085365590C3017618536 @default.
• W2085365590 hasConceptScore W2085365590C33923547 @default.

• next