FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085380017> ?p ?o ?g. }

• W2085380017 endingPage "711" @default.
• W2085380017 startingPage "710" @default.
• W2085380017 abstract "Chemical nucleases based on the transition-metal ions cleave DNA hydrolytically and/or oxidatively, with or without added reductant. We report here the novel DNA cleavage properties of the highly water-soluble, square-planar [Cu(Hpyrimol)Cl] complex, together with the results of cytotoxicities toward selected cancer cell lines. The copper complex cleaves PhiX174 supercoiled DNA efficiently without any reductant and shows high cytotoxicities toward L1210 murine leukemia and A2780 human ovarian carcinoma cancer cell lines that are sensitive and resistant to cisplatin. The IC50 values obtained for the copper complex in the sensitive cell lines are in the range of cisplatin, and for the cisplatin-resistant leukemia cell line, this value is even better." @default.
• W2085380017 created "2016-06-24" @default.
• W2085380017 creator A5005970123 @default.
• W2085380017 creator A5006875199 @default.
• W2085380017 creator A5012555611 @default.
• W2085380017 creator A5040171871 @default.
• W2085380017 creator A5047756003 @default.
• W2085380017 creator A5052318618 @default.
• W2085380017 creator A5079138321 @default.
• W2085380017 creator A5091052284 @default.
• W2085380017 date "2005-12-24" @default.
• W2085380017 modified "2023-10-16" @default.
• W2085380017 title "The Square-Planar Cytotoxic [Cu^II(pyrimol)Cl] Complex Acts as an Efficient DNA Cleaver without Reductant" @default.
• W2085380017 cites W1603675492 @default.
• W2085380017 cites W1992129618 @default.
• W2085380017 cites W2016711027 @default.
• W2085380017 cites W2022780899 @default.
• W2085380017 cites W2027784487 @default.
• W2085380017 cites W2047406811 @default.
• W2085380017 cites W2049191611 @default.
• W2085380017 cites W2094228553 @default.
• W2085380017 cites W2102127404 @default.
• W2085380017 cites W2102383161 @default.
• W2085380017 cites W4251268600 @default.
• W2085380017 doi "https://doi.org/10.1021/ja056970+" @default.
• W2085380017 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16417347" @default.
• W2085380017 hasPublicationYear "2005" @default.
• W2085380017 type Work @default.
• W2085380017 sameAs 2085380017 @default.
• W2085380017 citedByCount "192" @default.
• W2085380017 countsByYear W20853800172012 @default.
• W2085380017 countsByYear W20853800172013 @default.
• W2085380017 countsByYear W20853800172014 @default.
• W2085380017 countsByYear W20853800172015 @default.
• W2085380017 countsByYear W20853800172016 @default.
• W2085380017 countsByYear W20853800172017 @default.
• W2085380017 countsByYear W20853800172018 @default.
• W2085380017 countsByYear W20853800172019 @default.
• W2085380017 countsByYear W20853800172020 @default.
• W2085380017 countsByYear W20853800172021 @default.
• W2085380017 countsByYear W20853800172022 @default.
• W2085380017 countsByYear W20853800172023 @default.
• W2085380017 crossrefType "journal-article" @default.
• W2085380017 hasAuthorship W2085380017A5005970123 @default.
• W2085380017 hasAuthorship W2085380017A5006875199 @default.
• W2085380017 hasAuthorship W2085380017A5012555611 @default.
• W2085380017 hasAuthorship W2085380017A5040171871 @default.
• W2085380017 hasAuthorship W2085380017A5047756003 @default.
• W2085380017 hasAuthorship W2085380017A5052318618 @default.
• W2085380017 hasAuthorship W2085380017A5079138321 @default.
• W2085380017 hasAuthorship W2085380017A5091052284 @default.
• W2085380017 hasBestOaLocation W20853800172 @default.
• W2085380017 hasConcept C109316439 @default.
• W2085380017 hasConcept C121608353 @default.
• W2085380017 hasConcept C127413603 @default.
• W2085380017 hasConcept C154317977 @default.
• W2085380017 hasConcept C175156509 @default.
• W2085380017 hasConcept C178790620 @default.
• W2085380017 hasConcept C185592680 @default.
• W2085380017 hasConcept C187320778 @default.
• W2085380017 hasConcept C19014433 @default.
• W2085380017 hasConcept C202751555 @default.
• W2085380017 hasConcept C2776694085 @default.
• W2085380017 hasConcept C2778239845 @default.
• W2085380017 hasConcept C43369102 @default.
• W2085380017 hasConcept C54355233 @default.
• W2085380017 hasConcept C544153396 @default.
• W2085380017 hasConcept C544778455 @default.
• W2085380017 hasConcept C552990157 @default.
• W2085380017 hasConcept C55493867 @default.
• W2085380017 hasConcept C71240020 @default.
• W2085380017 hasConcept C81885089 @default.
• W2085380017 hasConcept C86803240 @default.
• W2085380017 hasConcept C96232424 @default.
• W2085380017 hasConceptScore W2085380017C109316439 @default.
• W2085380017 hasConceptScore W2085380017C121608353 @default.
• W2085380017 hasConceptScore W2085380017C127413603 @default.
• W2085380017 hasConceptScore W2085380017C154317977 @default.
• W2085380017 hasConceptScore W2085380017C175156509 @default.
• W2085380017 hasConceptScore W2085380017C178790620 @default.
• W2085380017 hasConceptScore W2085380017C185592680 @default.
• W2085380017 hasConceptScore W2085380017C187320778 @default.
• W2085380017 hasConceptScore W2085380017C19014433 @default.
• W2085380017 hasConceptScore W2085380017C202751555 @default.
• W2085380017 hasConceptScore W2085380017C2776694085 @default.
• W2085380017 hasConceptScore W2085380017C2778239845 @default.
• W2085380017 hasConceptScore W2085380017C43369102 @default.
• W2085380017 hasConceptScore W2085380017C54355233 @default.
• W2085380017 hasConceptScore W2085380017C544153396 @default.
• W2085380017 hasConceptScore W2085380017C544778455 @default.
• W2085380017 hasConceptScore W2085380017C552990157 @default.
• W2085380017 hasConceptScore W2085380017C55493867 @default.
• W2085380017 hasConceptScore W2085380017C71240020 @default.
• W2085380017 hasConceptScore W2085380017C81885089 @default.
• W2085380017 hasConceptScore W2085380017C86803240 @default.
• W2085380017 hasConceptScore W2085380017C96232424 @default.
• W2085380017 hasIssue "3" @default.
• W2085380017 hasLocation W20853800171 @default.

• next