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- W2085381159 abstract "In a large random mating population stable linkage disequilibrium occurs only when there is epistasis. However if a population is divided into a number of subpopulations among which migration occurs, stable linkage disequilibrium in each subpopulation may be produced without epistasis. In the case of two subpopulations a necessary condition for linkage equilibrium in the absence of epistasis is that at least at one of the two loci under consideration the gene frequency must be the same for the two populations. This condition is rather severe and any violation of this will lead to stable linkage disequilibrium. A similar conclusion can be made with more than two populations. In general the presence of linkage disequilibrium does not necessarily imply the existence of epistasis even in equilibrium populations." @default.
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- W2085381159 date "1974-10-01" @default.
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- W2085381159 title "Stable linkage disequilibrium without epistasis in subdivided populations" @default.
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- W2085381159 doi "https://doi.org/10.1016/0040-5809(74)90022-7" @default.
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