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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085387838> ?p ?o ?g. }

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• W2085387838 abstract "Sumatriptan is the first serotonin (5-hydroxytryptamine [5-HT](1B/1D)) receptor agonist specifically designed for the acute treatment of migraine. A new sumatriptan fast disintegrating/rapid release tablet (FDT/RRT) using RT technology has been developed to enhance tablet disintegration and dispersion in the stomach with the intention of speeding absorption and onset of effect, hence mitigating the effects on the gastrointestinal dysmotility that typically accompanies the attack. Sumatriptan FDT/RRT is bioequivalent to conventional tablets, although it provides slightly faster absorption during early post-dose interval. Clinical trials indicate that sumatriptan FDT/RRT is rapidly effective in terms of freedom from pain and return to normal activities, both with early and late treatment. The drug is well tolerated. In an oral formulation, which is the patients' preferred dosing route, sumatriptan FDT/RRT may therefore constitute an advance in the management of acute migraine attacks." @default.
• W2085387838 created "2016-06-24" @default.
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• W2085387838 date "2007-08-01" @default.
• W2085387838 modified "2023-10-13" @default.
• W2085387838 title "Sumatriptan fast-disintegrating/rapid-release tablets in the acute treatment of migraine" @default.
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• W2085387838 doi "https://doi.org/10.1586/14737175.7.8.927" @default.
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