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- W2085389958 abstract "A single injection of d-galactosamine given to rats at different times after partial hepatectomy (PH) changes the pattern of regenerative proliferation. When administered during the pre-replicative phase of regeneration, the onset of DNA synthesis and the increase in labelling index after injection of 3H-thymidine are delayed by about 12 hr. The injection of d-galactosamine at 24 hr after PH inhibits the drop in DNA synthesis occurring normally during the following 12 hr period. This was detected by a high labelling index and by an increased specific activity of DNA. The findings indicate a lengthening of the S phase, while G2 and M remain normal. Two modes of action of d-galactosamine on the cell cycle are discussed." @default.
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- W2085389958 date "1973-05-01" @default.
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- W2085389958 title "THE ALTERATION OF THE REGENERATIVE ACTIVITY AND THE CELL CYCLE OF PARTIALLY HEPATECTOMIZED RAT LIVER FOLLOWING ADMINISTRATION OF d-GALACTOSAMINE" @default.
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- W2085389958 doi "https://doi.org/10.1111/j.1365-2184.1973.tb01620.x" @default.
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