FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085391135> ?p ?o ?g. }

• W2085391135 endingPage "147" @default.
• W2085391135 startingPage "141" @default.
• W2085391135 abstract "Rotenone, an insecticide of botanical origin, causes toxicity through inhibition of complex I of the respiratory chain in mitochondria. This study was undertaken to determine whether rotenone-induced liver oxidant injury is prevented by erdosteine, a mucolytic agent showing antioxidant properties. There were four groups of Male Wistar Albino rats: group one was untreated as control; the other groups were treated with erdosteine (50 mg/kg per day, orally), rotenone (2.5 mg/mL once and 1 mL/kg per day for 60 days, i.p.) or rotenone plus erdosteine, respectively. Rotenone treatment without erdosteine increased xanthine oxidase (XO) enzyme activity and also increased lipid peroxidation in liver tissue (P < 0.05). The rats treated with rotenone plus erdosteine produced a significant decrease in lipid peroxidation and XO activities in comparison with rotenone group (P < 0.05). Erdosteine treatment with rotenone led to an increase in catalase (CAT) and superoxide dismutase (SOD) activities in comparison with the rotenone group (P < 0.05). There was no significant difference in nitric oxide (NO) level between groups. There were negative correlations between CAT activity and malondialdehyde (MDA) level (r = -0.934, P < 0.05) with between CAT and SOD activities (r = -0.714, P < 0.05), and a positive correlation between SOD activity and MDA level (r = 0.828, P < 0.05) in rotenone group. In the rotenone plus erdosteine group, there was a negative correlation between XO activity and NO level in liver tissue (r = -0.833, P < 0.05). In the light of these findings, erdosteine may be a protective agent for rotenone-induced liver oxidative injury in rats." @default.
• W2085391135 created "2016-06-24" @default.
• W2085391135 creator A5001486665 @default.
• W2085391135 creator A5007108681 @default.
• W2085391135 creator A5015957161 @default.
• W2085391135 creator A5036104109 @default.
• W2085391135 creator A5060281248 @default.
• W2085391135 creator A5070633442 @default.
• W2085391135 date "2004-07-01" @default.
• W2085391135 modified "2023-10-16" @default.
• W2085391135 title "Protective effects of erdosteine on rotenone-induced oxidant injury in liver tissue" @default.
• W2085391135 cites W1554017667 @default.
• W2085391135 cites W1775749144 @default.
• W2085391135 cites W1930159471 @default.
• W2085391135 cites W1954514489 @default.
• W2085391135 cites W1979378306 @default.
• W2085391135 cites W1980331802 @default.
• W2085391135 cites W1991079307 @default.
• W2085391135 cites W1992136740 @default.
• W2085391135 cites W2005773839 @default.
• W2085391135 cites W2007681259 @default.
• W2085391135 cites W2008904589 @default.
• W2085391135 cites W2024768658 @default.
• W2085391135 cites W2026525843 @default.
• W2085391135 cites W2037320248 @default.
• W2085391135 cites W2040932656 @default.
• W2085391135 cites W2048033372 @default.
• W2085391135 cites W2058584374 @default.
• W2085391135 cites W2062322625 @default.
• W2085391135 cites W2068045145 @default.
• W2085391135 cites W2071890640 @default.
• W2085391135 cites W2076009173 @default.
• W2085391135 cites W2077265524 @default.
• W2085391135 cites W2078642381 @default.
• W2085391135 cites W2084204140 @default.
• W2085391135 cites W2108291280 @default.
• W2085391135 cites W2141663828 @default.
• W2085391135 cites W2148071155 @default.
• W2085391135 cites W2159305277 @default.
• W2085391135 cites W3192879257 @default.
• W2085391135 cites W4205407119 @default.
• W2085391135 cites W76055556 @default.
• W2085391135 cites W969915667 @default.
• W2085391135 doi "https://doi.org/10.1191/0748233704th208oa" @default.
• W2085391135 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15941011" @default.
• W2085391135 hasPublicationYear "2004" @default.
• W2085391135 type Work @default.
• W2085391135 sameAs 2085391135 @default.
• W2085391135 citedByCount "28" @default.
• W2085391135 countsByYear W20853911352012 @default.
• W2085391135 countsByYear W20853911352016 @default.
• W2085391135 countsByYear W20853911352017 @default.
• W2085391135 countsByYear W20853911352018 @default.
• W2085391135 countsByYear W20853911352019 @default.
• W2085391135 countsByYear W20853911352020 @default.
• W2085391135 countsByYear W20853911352021 @default.
• W2085391135 countsByYear W20853911352022 @default.
• W2085391135 crossrefType "journal-article" @default.
• W2085391135 hasAuthorship W2085391135A5001486665 @default.
• W2085391135 hasAuthorship W2085391135A5007108681 @default.
• W2085391135 hasAuthorship W2085391135A5015957161 @default.
• W2085391135 hasAuthorship W2085391135A5036104109 @default.
• W2085391135 hasAuthorship W2085391135A5060281248 @default.
• W2085391135 hasAuthorship W2085391135A5070633442 @default.
• W2085391135 hasConcept C181199279 @default.
• W2085391135 hasConcept C185592680 @default.
• W2085391135 hasConcept C2775838275 @default.
• W2085391135 hasConcept C2778004101 @default.
• W2085391135 hasConcept C2778102346 @default.
• W2085391135 hasConcept C2778389096 @default.
• W2085391135 hasConcept C2778401633 @default.
• W2085391135 hasConcept C2778979269 @default.
• W2085391135 hasConcept C2780829032 @default.
• W2085391135 hasConcept C28859421 @default.
• W2085391135 hasConcept C55493867 @default.
• W2085391135 hasConcept C86803240 @default.
• W2085391135 hasConcept C98274493 @default.
• W2085391135 hasConceptScore W2085391135C181199279 @default.
• W2085391135 hasConceptScore W2085391135C185592680 @default.
• W2085391135 hasConceptScore W2085391135C2775838275 @default.
• W2085391135 hasConceptScore W2085391135C2778004101 @default.
• W2085391135 hasConceptScore W2085391135C2778102346 @default.
• W2085391135 hasConceptScore W2085391135C2778389096 @default.
• W2085391135 hasConceptScore W2085391135C2778401633 @default.
• W2085391135 hasConceptScore W2085391135C2778979269 @default.
• W2085391135 hasConceptScore W2085391135C2780829032 @default.
• W2085391135 hasConceptScore W2085391135C28859421 @default.
• W2085391135 hasConceptScore W2085391135C55493867 @default.
• W2085391135 hasConceptScore W2085391135C86803240 @default.
• W2085391135 hasConceptScore W2085391135C98274493 @default.
• W2085391135 hasIssue "6-10" @default.
• W2085391135 hasLocation W20853911351 @default.
• W2085391135 hasLocation W20853911352 @default.
• W2085391135 hasOpenAccess W2085391135 @default.
• W2085391135 hasPrimaryLocation W20853911351 @default.
• W2085391135 hasRelatedWork W1533244249 @default.
• W2085391135 hasRelatedWork W155744969 @default.
• W2085391135 hasRelatedWork W2183540883 @default.

• next