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- W2085393281 abstract "Abstract The present manuscript describes an electrochemical assay for detection of different types of single base mismatches (SBM) using 3,4-diaminobenzoic acid (DABA) as a new redox reporter. DABA is covalently attached to DNA, and its electrochemical response is followed. The present assay can overcome to two main problems of the hybridization biosensors, direct electron transfer of the redox reporter with the electrode surface and the positioning of the reporter before mismatch position. The introduced biosensor is able to discriminate complementary target and the targets including a single base mismatch even thermodynamically stable ones such as G–A and G–T." @default.
- W2085393281 created "2016-06-24" @default.
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- W2085393281 date "2011-11-01" @default.
- W2085393281 modified "2023-10-03" @default.
- W2085393281 title "3,4-Diaminobenzoic acid (DABA) as a redox label for electrochemical detection of single base mismatches" @default.
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- W2085393281 doi "https://doi.org/10.1016/j.electacta.2011.09.014" @default.
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