FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085397430> ?p ?o ?g. }

• W2085397430 endingPage "207" @default.
• W2085397430 startingPage "198" @default.
• W2085397430 abstract "This study compares the diagnostic accuracy of magnetic resonance (MR)-based hippocampal volumetry, single voxel (1)H MR spectroscopy ((1)H MRS) and MR diffusion-weighted imaging (DWI) measurements in discriminating patients with amnestic mild cognitive impairment (MCI), Alzheimer's disease (AD) and normally aging elderly. Sixty-one normally aging elderly, 24 MCI and 22 AD patients underwent MR-based hippocampal volumetry, (1)H MRS and DWI. (1)H MRS voxels were placed over both of the posterior cingulate gyri, and N-acetyl aspartate (NAA)/creatine (Cr), myoinositol (MI)/Cr and NAA/MI ratios were obtained. Apparent diffusion coefficient (ADC) maps were derived from DWI, and hippocampal borders were traced to measure hippocampal ADC. At 80% specificity, the most sensitive single measurement to discriminate MCI (79%) and AD (86%) from controls was hippocampal volumes. The most sensitive single measurement to discriminate AD from MCI was posterior cingulate gyrus NAA/Cr (67%). At high specificity (>85-90%), combinations of MR measures had superior diagnostic sensitivity compared with any single MR measurement for the AD vs. control and control vs. MCI comparisons. The MR measures that best discriminate more from less affected individuals along the cognitive continuum from normal to AD vary with disease severity. Selection of imaging measures used for clinical assessment or monitoring efficiency of therapeutic intervention should be tailored to the clinical stage of the disease." @default.
• W2085397430 created "2016-06-24" @default.
• W2085397430 creator A5005099850 @default.
• W2085397430 creator A5024077089 @default.
• W2085397430 creator A5027180655 @default.
• W2085397430 creator A5029563824 @default.
• W2085397430 creator A5032261479 @default.
• W2085397430 creator A5032320906 @default.
• W2085397430 creator A5045246745 @default.
• W2085397430 creator A5053703908 @default.
• W2085397430 creator A5057698408 @default.
• W2085397430 creator A5066352714 @default.
• W2085397430 creator A5076444858 @default.
• W2085397430 creator A5077933873 @default.
• W2085397430 creator A5090943173 @default.
• W2085397430 date "2002-01-01" @default.
• W2085397430 modified "2023-10-17" @default.
• W2085397430 title "Comparative Diagnostic Utility of Different MR Modalities in Mild Cognitive Impairment and Alzheimer’s Disease" @default.
• W2085397430 cites W129377199 @default.
• W2085397430 cites W1693283493 @default.
• W2085397430 cites W1847168837 @default.
• W2085397430 cites W1964142865 @default.
• W2085397430 cites W1976076281 @default.
• W2085397430 cites W1984229043 @default.
• W2085397430 cites W1985612893 @default.
• W2085397430 cites W1990039754 @default.
• W2085397430 cites W1991886821 @default.
• W2085397430 cites W1991952617 @default.
• W2085397430 cites W2001210466 @default.
• W2085397430 cites W2008854521 @default.
• W2085397430 cites W2011427707 @default.
• W2085397430 cites W2012215271 @default.
• W2085397430 cites W2023121717 @default.
• W2085397430 cites W2025915778 @default.
• W2085397430 cites W2030567293 @default.
• W2085397430 cites W2033800655 @default.
• W2085397430 cites W2042514413 @default.
• W2085397430 cites W2046429594 @default.
• W2085397430 cites W2049362778 @default.
• W2085397430 cites W2052742260 @default.
• W2085397430 cites W2058161128 @default.
• W2085397430 cites W2060786719 @default.
• W2085397430 cites W2063136428 @default.
• W2085397430 cites W2072691846 @default.
• W2085397430 cites W2083865676 @default.
• W2085397430 cites W2083892829 @default.
• W2085397430 cites W2084424457 @default.
• W2085397430 cites W2086978209 @default.
• W2085397430 cites W2093488421 @default.
• W2085397430 cites W2094542668 @default.
• W2085397430 cites W2104517703 @default.
• W2085397430 cites W2115077024 @default.
• W2085397430 cites W2124114508 @default.
• W2085397430 cites W2128776571 @default.
• W2085397430 cites W2143731392 @default.
• W2085397430 cites W2144631174 @default.
• W2085397430 cites W2146124752 @default.
• W2085397430 cites W2148080316 @default.
• W2085397430 cites W2156220037 @default.
• W2085397430 cites W2159122349 @default.
• W2085397430 cites W2164398286 @default.
• W2085397430 cites W2167311298 @default.
• W2085397430 cites W4246463936 @default.
• W2085397430 cites W4249221250 @default.
• W2085397430 doi "https://doi.org/10.1159/000066021" @default.
• W2085397430 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2796574" @default.
• W2085397430 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12411762" @default.
• W2085397430 hasPublicationYear "2002" @default.
• W2085397430 type Work @default.
• W2085397430 sameAs 2085397430 @default.
• W2085397430 citedByCount "137" @default.
• W2085397430 countsByYear W20853974302012 @default.
• W2085397430 countsByYear W20853974302013 @default.
• W2085397430 countsByYear W20853974302014 @default.
• W2085397430 countsByYear W20853974302015 @default.
• W2085397430 countsByYear W20853974302017 @default.
• W2085397430 countsByYear W20853974302018 @default.
• W2085397430 countsByYear W20853974302020 @default.
• W2085397430 countsByYear W20853974302021 @default.
• W2085397430 countsByYear W20853974302022 @default.
• W2085397430 countsByYear W20853974302023 @default.
• W2085397430 crossrefType "journal-article" @default.
• W2085397430 hasAuthorship W2085397430A5005099850 @default.
• W2085397430 hasAuthorship W2085397430A5024077089 @default.
• W2085397430 hasAuthorship W2085397430A5027180655 @default.
• W2085397430 hasAuthorship W2085397430A5029563824 @default.
• W2085397430 hasAuthorship W2085397430A5032261479 @default.
• W2085397430 hasAuthorship W2085397430A5032320906 @default.
• W2085397430 hasAuthorship W2085397430A5045246745 @default.
• W2085397430 hasAuthorship W2085397430A5053703908 @default.
• W2085397430 hasAuthorship W2085397430A5057698408 @default.
• W2085397430 hasAuthorship W2085397430A5066352714 @default.
• W2085397430 hasAuthorship W2085397430A5076444858 @default.
• W2085397430 hasAuthorship W2085397430A5077933873 @default.
• W2085397430 hasAuthorship W2085397430A5090943173 @default.
• W2085397430 hasBestOaLocation W20853974302 @default.
• W2085397430 hasConcept C126322002 @default.
• W2085397430 hasConcept C126838900 @default.

• next