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- W2085402824 abstract "Oral administration of embelin (75 mg/kg per day, daily for 15 and 30 days) to male rats caused significant elevation in the uptake of D-glucose, L-alanine, L-leucine and calcium in small intestinal segments. Embelin also produced significant increases in intestinal brush border membrane-associated enzymes (sucrase, lactase, maltase, alkaline phosphatase and leucine aminopeptidase) in both intestinal homogenates and partially purified brush border membrane preparations. Significant increases were also noted for microsomal glucose-6-phosphatase and cytosolic lactate dehydrogenase. Increase in brush border membrane-associated total lipids, phospholipids, cholesterol, triacylglycerol, unesterified fatty acids and ganglioside sialic acid were seen but not in the cholesterol/phospholipid molar ratio. All these changes returned to control or near control levels following withdrawal of the drug." @default.
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- W2085402824 date "1991-07-01" @default.
- W2085402824 modified "2023-09-24" @default.
- W2085402824 title "Effects of embelin, a male antifertility agent, on absorptive and digestive functions of rat intestine" @default.
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- W2085402824 doi "https://doi.org/10.1016/0378-8741(91)90077-q" @default.
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