Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085406903> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2085406903 endingPage "695" @default.
- W2085406903 startingPage "690" @default.
- W2085406903 abstract "The arachidonic acid metabolite of 12 lipoxygenase, 12(S)-hydroxyeicosatetraenoic acid (12(S)-HETE) promotes metastatic behavior of tumor cells. In this study we set out to identify 12(S)-HETE signaling pathways, and their contribution to cellular functions in A431 epidermoid carcinoma. (1) 12(S)-HETE stimulated phosphotyrosine associated PI3 kinase activity. (2) 12(S)-HETE stimulated ERK1/2 in a PI3 kinase dependent manner. (3) PI3 kinase affected the 12(S)-HETE stimulated Raf/MEK/ERK cascade at the level of MEK. (4) 12(S)-HETE stimulated ERK1/2 via PKCzeta. (5) 12(S)-HETE stimulated cell migration on laminin, which was eliminated by PI3 kinase and cPKC inhibitors, but it was unaffected by inhibition of ERK1/2." @default.
- W2085406903 created "2016-06-24" @default.
- W2085406903 creator A5001222065 @default.
- W2085406903 creator A5001907834 @default.
- W2085406903 creator A5044817021 @default.
- W2085406903 creator A5066469501 @default.
- W2085406903 date "2000-08-01" @default.
- W2085406903 modified "2023-10-05" @default.
- W2085406903 title "Eicosanoid 12(S)-HETE Activates Phosphatidylinositol 3-Kinase" @default.
- W2085406903 cites W1579531 @default.
- W2085406903 cites W1791888878 @default.
- W2085406903 cites W1971719930 @default.
- W2085406903 cites W1977795081 @default.
- W2085406903 cites W1987883076 @default.
- W2085406903 cites W1995495200 @default.
- W2085406903 cites W2020625292 @default.
- W2085406903 cites W2042733728 @default.
- W2085406903 cites W2048861137 @default.
- W2085406903 cites W2050281512 @default.
- W2085406903 cites W2053313289 @default.
- W2085406903 cites W2055245856 @default.
- W2085406903 cites W205984844 @default.
- W2085406903 cites W2062904912 @default.
- W2085406903 cites W2066253845 @default.
- W2085406903 cites W2069826620 @default.
- W2085406903 cites W2081324739 @default.
- W2085406903 cites W2109283410 @default.
- W2085406903 cites W2138231208 @default.
- W2085406903 cites W4243559800 @default.
- W2085406903 cites W44016002 @default.
- W2085406903 doi "https://doi.org/10.1006/bbrc.2000.3348" @default.
- W2085406903 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10964724" @default.
- W2085406903 hasPublicationYear "2000" @default.
- W2085406903 type Work @default.
- W2085406903 sameAs 2085406903 @default.
- W2085406903 citedByCount "30" @default.
- W2085406903 countsByYear W20854069032012 @default.
- W2085406903 countsByYear W20854069032013 @default.
- W2085406903 countsByYear W20854069032018 @default.
- W2085406903 countsByYear W20854069032020 @default.
- W2085406903 crossrefType "journal-article" @default.
- W2085406903 hasAuthorship W2085406903A5001222065 @default.
- W2085406903 hasAuthorship W2085406903A5001907834 @default.
- W2085406903 hasAuthorship W2085406903A5044817021 @default.
- W2085406903 hasAuthorship W2085406903A5066469501 @default.
- W2085406903 hasBestOaLocation W20854069031 @default.
- W2085406903 hasConcept C181199279 @default.
- W2085406903 hasConcept C184235292 @default.
- W2085406903 hasConcept C185592680 @default.
- W2085406903 hasConcept C195794163 @default.
- W2085406903 hasConcept C2776352991 @default.
- W2085406903 hasConcept C2777477808 @default.
- W2085406903 hasConcept C2778078955 @default.
- W2085406903 hasConcept C2779630222 @default.
- W2085406903 hasConcept C2780610907 @default.
- W2085406903 hasConcept C55493867 @default.
- W2085406903 hasConcept C57074206 @default.
- W2085406903 hasConcept C86803240 @default.
- W2085406903 hasConcept C95444343 @default.
- W2085406903 hasConcept C97029542 @default.
- W2085406903 hasConceptScore W2085406903C181199279 @default.
- W2085406903 hasConceptScore W2085406903C184235292 @default.
- W2085406903 hasConceptScore W2085406903C185592680 @default.
- W2085406903 hasConceptScore W2085406903C195794163 @default.
- W2085406903 hasConceptScore W2085406903C2776352991 @default.
- W2085406903 hasConceptScore W2085406903C2777477808 @default.
- W2085406903 hasConceptScore W2085406903C2778078955 @default.
- W2085406903 hasConceptScore W2085406903C2779630222 @default.
- W2085406903 hasConceptScore W2085406903C2780610907 @default.
- W2085406903 hasConceptScore W2085406903C55493867 @default.
- W2085406903 hasConceptScore W2085406903C57074206 @default.
- W2085406903 hasConceptScore W2085406903C86803240 @default.
- W2085406903 hasConceptScore W2085406903C95444343 @default.
- W2085406903 hasConceptScore W2085406903C97029542 @default.
- W2085406903 hasIssue "2" @default.
- W2085406903 hasLocation W20854069031 @default.
- W2085406903 hasLocation W20854069032 @default.
- W2085406903 hasOpenAccess W2085406903 @default.
- W2085406903 hasPrimaryLocation W20854069031 @default.
- W2085406903 hasRelatedWork W1966143034 @default.
- W2085406903 hasRelatedWork W2000775162 @default.
- W2085406903 hasRelatedWork W2005115885 @default.
- W2085406903 hasRelatedWork W2023027368 @default.
- W2085406903 hasRelatedWork W2025794474 @default.
- W2085406903 hasRelatedWork W2033392642 @default.
- W2085406903 hasRelatedWork W2053995479 @default.
- W2085406903 hasRelatedWork W2085406903 @default.
- W2085406903 hasRelatedWork W2115893235 @default.
- W2085406903 hasRelatedWork W2129262313 @default.
- W2085406903 hasVolume "275" @default.
- W2085406903 isParatext "false" @default.
- W2085406903 isRetracted "false" @default.
- W2085406903 magId "2085406903" @default.
- W2085406903 workType "article" @default.