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- W2085424871 abstract "Eight indices of thyroid function (total and free serum-thyroxine concentration, free-thyroxine fraction, thyroxine/thyroxine-binding-globulin ratio, 4 and 24 hour thyroidal uptake of radioiodine, 48-hour protein-bound 131I, and the score on the Wayne clinical diagnostic index for thyrotoxicosis) were measured and compared in each of 105 patients with thyrotoxicosis. All patients had an abnormally raised free thyroxine concentration, but with each of the other tests a variable number of patients had results within the normal range. There was a significant negative correlation between the Wayne index score and the age of the patient, confirming the long-held impression that the clinical diagnosis of thyrotoxicosis is more difficult in older patients. The clinical severity of thyrotoxicosis (as judged by the Wayne index) was compared with the value obtained in each of the other indices of thyroid function. Clinical severity was more closely related to the free-thyroxine concentration than to any other index." @default.
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- W2085424871 date "1971-07-01" @default.
- W2085424871 modified "2023-09-26" @default.
- W2085424871 title "INDICES OF THYROID FUNCTION IN THYROTOXICOSIS" @default.
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- W2085424871 doi "https://doi.org/10.1016/s0140-6736(71)92571-2" @default.
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