Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085438574> ?p ?o ?g. }
- W2085438574 endingPage "85" @default.
- W2085438574 startingPage "69" @default.
- W2085438574 abstract "Thyroid hormones (THs) are well-known regulators of development and metabolism in vertebrates. There is increasing evidence that THs are also involved in gonadal differentiation and reproductive function. Changes in TH status affect sex ratios in developing fish and frogs and reproduction (e.g., fertility), hormone levels, and gonad morphology in adults of species of different vertebrates. In this review, we have summarized and compared the evidence for cross-talk between the steroid hormone and thyroid axes and present a comparative model. We gave special attention to TH regulation of sex steroid synthesis and action in both the brain and gonad, since these are important for gonad development and brain sexual differentiation and have been studied in many species. We also reviewed research showing that there is a TH system, including receptors and enzymes, in the brains and gonads in developing and adult vertebrates. Our analysis shows that THs influences sex steroid hormone synthesis in vertebrates, ranging from fish to pigs. This concept of crosstalk and conserved hormone interaction has implications for our understanding of the role of THs in reproduction, and how these processes may be dysregulated by environmental endocrine disruptors." @default.
- W2085438574 created "2016-06-24" @default.
- W2085438574 creator A5004819710 @default.
- W2085438574 creator A5030364803 @default.
- W2085438574 creator A5030415599 @default.
- W2085438574 date "2014-07-01" @default.
- W2085438574 modified "2023-10-06" @default.
- W2085438574 title "Mechanisms of crosstalk between endocrine systems: Regulation of sex steroid hormone synthesis and action by thyroid hormones" @default.
- W2085438574 cites W1481088207 @default.
- W2085438574 cites W1488284274 @default.
- W2085438574 cites W1545293228 @default.
- W2085438574 cites W1799555931 @default.
- W2085438574 cites W1878714921 @default.
- W2085438574 cites W1963655571 @default.
- W2085438574 cites W1963852628 @default.
- W2085438574 cites W1966095570 @default.
- W2085438574 cites W1966396293 @default.
- W2085438574 cites W1966814250 @default.
- W2085438574 cites W1968156993 @default.
- W2085438574 cites W1968182297 @default.
- W2085438574 cites W1969311370 @default.
- W2085438574 cites W1969658536 @default.
- W2085438574 cites W1970723205 @default.
- W2085438574 cites W1970738581 @default.
- W2085438574 cites W1971532261 @default.
- W2085438574 cites W1971547524 @default.
- W2085438574 cites W1972455454 @default.
- W2085438574 cites W1973001565 @default.
- W2085438574 cites W1973145170 @default.
- W2085438574 cites W1975271115 @default.
- W2085438574 cites W1976180326 @default.
- W2085438574 cites W1976893802 @default.
- W2085438574 cites W1977672570 @default.
- W2085438574 cites W1978357546 @default.
- W2085438574 cites W1980777228 @default.
- W2085438574 cites W1980887286 @default.
- W2085438574 cites W1981225485 @default.
- W2085438574 cites W1981349281 @default.
- W2085438574 cites W1981613842 @default.
- W2085438574 cites W1982349265 @default.
- W2085438574 cites W1982690749 @default.
- W2085438574 cites W1983352700 @default.
- W2085438574 cites W1983740037 @default.
- W2085438574 cites W1984484185 @default.
- W2085438574 cites W1984638038 @default.
- W2085438574 cites W1986012379 @default.
- W2085438574 cites W1986296716 @default.
- W2085438574 cites W1986592068 @default.
- W2085438574 cites W1986792671 @default.
- W2085438574 cites W1988046189 @default.
- W2085438574 cites W1988377203 @default.
- W2085438574 cites W1990111519 @default.
- W2085438574 cites W1990168204 @default.
- W2085438574 cites W1990430586 @default.
- W2085438574 cites W1990621415 @default.
- W2085438574 cites W1991106516 @default.
- W2085438574 cites W1991593658 @default.
- W2085438574 cites W1992534907 @default.
- W2085438574 cites W1992535192 @default.
- W2085438574 cites W1992885955 @default.
- W2085438574 cites W1993094775 @default.
- W2085438574 cites W1993306257 @default.
- W2085438574 cites W1993599204 @default.
- W2085438574 cites W1994349548 @default.
- W2085438574 cites W1994930939 @default.
- W2085438574 cites W1995675407 @default.
- W2085438574 cites W1996689072 @default.
- W2085438574 cites W1996709691 @default.
- W2085438574 cites W1997825005 @default.
- W2085438574 cites W1998690351 @default.
- W2085438574 cites W1999434762 @default.
- W2085438574 cites W2000440473 @default.
- W2085438574 cites W2000632853 @default.
- W2085438574 cites W2001101267 @default.
- W2085438574 cites W2001641056 @default.
- W2085438574 cites W2002151843 @default.
- W2085438574 cites W2002653885 @default.
- W2085438574 cites W2003631076 @default.
- W2085438574 cites W2003664007 @default.
- W2085438574 cites W2004120736 @default.
- W2085438574 cites W2004782543 @default.
- W2085438574 cites W2007015697 @default.
- W2085438574 cites W2008168193 @default.
- W2085438574 cites W2008765525 @default.
- W2085438574 cites W2009140418 @default.
- W2085438574 cites W2009172873 @default.
- W2085438574 cites W2009896776 @default.
- W2085438574 cites W2010139764 @default.
- W2085438574 cites W2011626153 @default.
- W2085438574 cites W2011700227 @default.
- W2085438574 cites W2012139589 @default.
- W2085438574 cites W2012210313 @default.
- W2085438574 cites W2012266374 @default.
- W2085438574 cites W2012321949 @default.
- W2085438574 cites W2012366655 @default.
- W2085438574 cites W2013060222 @default.
- W2085438574 cites W2014961652 @default.
- W2085438574 cites W2015293028 @default.