FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085447804> ?p ?o ?g. }

• W2085447804 endingPage "4875" @default.
• W2085447804 startingPage "4872" @default.
• W2085447804 abstract "Three 21 bp repeats can be found in the bovine leukemia virus long terminal repeat, which are crucial for the LTR directed gene expression by the trans activator protein Tax. Previous studies demonstrated that the major target of the Tax directed activation are the CRE-like elements in the center of these repeats. In this work we report that another motif of the 21 bp repeats is also required for the Tax activation. Gel retardation — with the wild type or mutant 21 bp repeats — revealed that cellular factors from HeLa cells were specifically bound to the center (CRE-like element) and the 3′ region of the repeats, which contains a CAGCTG consensus AP-4 binding site. In vivo analysis using the synthetic 21 bp repeats indicated that beyond the consensus CRE-like motif, the AP-4 site is also essential for Tax activation. To determine the role of AP-4 in BLV Tax trans activation, we used the AP-4 cDNA in antisense transient assays. In the in vivo experiments the antisense AP-4 RNA resulted in strongly decreased Tax activation. On the basis of these results we conclude that AP-4 is a good candidate of cellular factors involved in BLV Tax trans activation." @default.
• W2085447804 created "2016-06-24" @default.
• W2085447804 creator A5041490644 @default.
• W2085447804 creator A5048805175 @default.
• W2085447804 creator A5066237467 @default.
• W2085447804 date "1994-01-01" @default.
• W2085447804 modified "2023-10-18" @default.
• W2085447804 title "Transcription factor AP-4 participates in activation of bovine leukemia virus long terminal repeat by p34 Tax" @default.
• W2085447804 cites W1539006922 @default.
• W2085447804 cites W1559919026 @default.
• W2085447804 cites W1571524031 @default.
• W2085447804 cites W1892064464 @default.
• W2085447804 cites W1964733862 @default.
• W2085447804 cites W1993243592 @default.
• W2085447804 cites W2003708679 @default.
• W2085447804 cites W2007032319 @default.
• W2085447804 cites W2011509827 @default.
• W2085447804 cites W2016655706 @default.
• W2085447804 cites W2019429132 @default.
• W2085447804 cites W2059269241 @default.
• W2085447804 cites W2061917886 @default.
• W2085447804 cites W2082670705 @default.
• W2085447804 cites W2108490725 @default.
• W2085447804 cites W2144206181 @default.
• W2085447804 cites W2145085539 @default.
• W2085447804 cites W2151869342 @default.
• W2085447804 cites W2166481738 @default.
• W2085447804 cites W2217856650 @default.
• W2085447804 cites W2416022039 @default.
• W2085447804 cites W315180324 @default.
• W2085447804 doi "https://doi.org/10.1093/nar/22.23.4872" @default.
• W2085447804 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/523750" @default.
• W2085447804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7800474" @default.
• W2085447804 hasPublicationYear "1994" @default.
• W2085447804 type Work @default.
• W2085447804 sameAs 2085447804 @default.
• W2085447804 citedByCount "30" @default.
• W2085447804 countsByYear W20854478042012 @default.
• W2085447804 countsByYear W20854478042015 @default.
• W2085447804 countsByYear W20854478042016 @default.
• W2085447804 countsByYear W20854478042020 @default.
• W2085447804 countsByYear W20854478042021 @default.
• W2085447804 countsByYear W20854478042022 @default.
• W2085447804 countsByYear W20854478042023 @default.
• W2085447804 crossrefType "journal-article" @default.
• W2085447804 hasAuthorship W2085447804A5041490644 @default.
• W2085447804 hasAuthorship W2085447804A5048805175 @default.
• W2085447804 hasAuthorship W2085447804A5066237467 @default.
• W2085447804 hasBestOaLocation W20854478042 @default.
• W2085447804 hasConcept C104317684 @default.
• W2085447804 hasConcept C138885662 @default.
• W2085447804 hasConcept C141231307 @default.
• W2085447804 hasConcept C150194340 @default.
• W2085447804 hasConcept C153911025 @default.
• W2085447804 hasConcept C179926584 @default.
• W2085447804 hasConcept C199491388 @default.
• W2085447804 hasConcept C2522874641 @default.
• W2085447804 hasConcept C2778645089 @default.
• W2085447804 hasConcept C29511175 @default.
• W2085447804 hasConcept C41895202 @default.
• W2085447804 hasConcept C54355233 @default.
• W2085447804 hasConcept C86803240 @default.
• W2085447804 hasConcept C88045685 @default.
• W2085447804 hasConceptScore W2085447804C104317684 @default.
• W2085447804 hasConceptScore W2085447804C138885662 @default.
• W2085447804 hasConceptScore W2085447804C141231307 @default.
• W2085447804 hasConceptScore W2085447804C150194340 @default.
• W2085447804 hasConceptScore W2085447804C153911025 @default.
• W2085447804 hasConceptScore W2085447804C179926584 @default.
• W2085447804 hasConceptScore W2085447804C199491388 @default.
• W2085447804 hasConceptScore W2085447804C2522874641 @default.
• W2085447804 hasConceptScore W2085447804C2778645089 @default.
• W2085447804 hasConceptScore W2085447804C29511175 @default.
• W2085447804 hasConceptScore W2085447804C41895202 @default.
• W2085447804 hasConceptScore W2085447804C54355233 @default.
• W2085447804 hasConceptScore W2085447804C86803240 @default.
• W2085447804 hasConceptScore W2085447804C88045685 @default.
• W2085447804 hasIssue "23" @default.
• W2085447804 hasLocation W20854478041 @default.
• W2085447804 hasLocation W20854478042 @default.
• W2085447804 hasLocation W20854478043 @default.
• W2085447804 hasLocation W20854478044 @default.
• W2085447804 hasOpenAccess W2085447804 @default.
• W2085447804 hasPrimaryLocation W20854478041 @default.
• W2085447804 hasRelatedWork W1981630280 @default.
• W2085447804 hasRelatedWork W1988333200 @default.
• W2085447804 hasRelatedWork W2050614068 @default.
• W2085447804 hasRelatedWork W2056639233 @default.
• W2085447804 hasRelatedWork W2279535460 @default.
• W2085447804 hasRelatedWork W2431653593 @default.
• W2085447804 hasRelatedWork W2462535801 @default.
• W2085447804 hasRelatedWork W2947934032 @default.
• W2085447804 hasRelatedWork W2951884817 @default.
• W2085447804 hasRelatedWork W3093201963 @default.
• W2085447804 hasVolume "22" @default.
• W2085447804 isParatext "false" @default.
• W2085447804 isRetracted "false" @default.
• W2085447804 magId "2085447804" @default.

• next