FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085455080> ?p ?o ?g. }

• W2085455080 endingPage "205" @default.
• W2085455080 startingPage "197" @default.
• W2085455080 abstract "Multiple sclerosis (MS) is an inflammatory demyelinating disease characterised by immune abnormalities in the central nervous system (CNS) as well as systemically. Activated, blood-borne monocytes are abundant in MS lesions, the properties of circulating monocytes are incompletely known. To delineate phenotype and levels of cytokine secreting monocytes in MS patients' blood, ELISPOT assays were used for detection and enumeration of monocytes secreting the cytokines IL-6, IL-12, TNF-alpha and IL-10. In parallel, the expression by monocytes of co-stimulatory molecules (CD40, CD80, CD86), major histocompatibility complex molecules (HLA-ABC, HLA-DR) and Fcgamma receptors (CD16, CD64) was examined by flow cytometry. Levels of blood monocytes secreting IL-6 and IL-12 were higher in patients with untreated MS and other neurological diseases (OND) compared to healthy controls, while levels of monocytes secreting TNF-alpha and IL-10 did not differ between groups. MS patients' blood monocytes also displayed elevated mean fluorescence intensity for the co-stimulatory molecule CD86, and MS patients with longer disease duration (>10 years) and higher disease severity (EDSS >3) had higher percentages of CD80 expressing monocytes compared to patients with short duration or lower severity. In conclusion, monocyte aberrations occur in MS and may change over the disease course." @default.
• W2085455080 created "2016-06-24" @default.
• W2085455080 creator A5001144400 @default.
• W2085455080 creator A5019252731 @default.
• W2085455080 creator A5022127785 @default.
• W2085455080 creator A5037395192 @default.
• W2085455080 creator A5058005265 @default.
• W2085455080 date "2001-01-01" @default.
• W2085455080 modified "2023-10-18" @default.
• W2085455080 title "Monocytes in multiple sclerosis: phenotype and cytokine profile" @default.
• W2085455080 cites W1486973386 @default.
• W2085455080 cites W1970140843 @default.
• W2085455080 cites W1972193564 @default.
• W2085455080 cites W1977271916 @default.
• W2085455080 cites W1990840926 @default.
• W2085455080 cites W2000721338 @default.
• W2085455080 cites W2000872418 @default.
• W2085455080 cites W2001745004 @default.
• W2085455080 cites W2004219852 @default.
• W2085455080 cites W2010545917 @default.
• W2085455080 cites W2014049271 @default.
• W2085455080 cites W2016895993 @default.
• W2085455080 cites W2017187068 @default.
• W2085455080 cites W2017347652 @default.
• W2085455080 cites W2023206738 @default.
• W2085455080 cites W2041508820 @default.
• W2085455080 cites W2043127031 @default.
• W2085455080 cites W2049878941 @default.
• W2085455080 cites W2050753578 @default.
• W2085455080 cites W2052701260 @default.
• W2085455080 cites W2065479473 @default.
• W2085455080 cites W2069347052 @default.
• W2085455080 cites W2078450673 @default.
• W2085455080 cites W2079242778 @default.
• W2085455080 cites W2079336414 @default.
• W2085455080 cites W2085330430 @default.
• W2085455080 cites W2091768626 @default.
• W2085455080 cites W2101520046 @default.
• W2085455080 cites W2126972494 @default.
• W2085455080 cites W2130355701 @default.
• W2085455080 cites W2135566895 @default.
• W2085455080 cites W2141636226 @default.
• W2085455080 cites W2142177598 @default.
• W2085455080 cites W2150428768 @default.
• W2085455080 cites W2152932110 @default.
• W2085455080 cites W2162440323 @default.
• W2085455080 cites W4313333777 @default.
• W2085455080 cites W4313343461 @default.
• W2085455080 doi "https://doi.org/10.1016/s0165-5728(00)00396-9" @default.
• W2085455080 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11108949" @default.
• W2085455080 hasPublicationYear "2001" @default.
• W2085455080 type Work @default.
• W2085455080 sameAs 2085455080 @default.
• W2085455080 citedByCount "79" @default.
• W2085455080 countsByYear W20854550802012 @default.
• W2085455080 countsByYear W20854550802013 @default.
• W2085455080 countsByYear W20854550802014 @default.
• W2085455080 countsByYear W20854550802015 @default.
• W2085455080 countsByYear W20854550802016 @default.
• W2085455080 countsByYear W20854550802017 @default.
• W2085455080 countsByYear W20854550802018 @default.
• W2085455080 countsByYear W20854550802019 @default.
• W2085455080 countsByYear W20854550802020 @default.
• W2085455080 countsByYear W20854550802021 @default.
• W2085455080 countsByYear W20854550802022 @default.
• W2085455080 countsByYear W20854550802023 @default.
• W2085455080 crossrefType "journal-article" @default.
• W2085455080 hasAuthorship W2085455080A5001144400 @default.
• W2085455080 hasAuthorship W2085455080A5019252731 @default.
• W2085455080 hasAuthorship W2085455080A5022127785 @default.
• W2085455080 hasAuthorship W2085455080A5037395192 @default.
• W2085455080 hasAuthorship W2085455080A5058005265 @default.
• W2085455080 hasConcept C114684123 @default.
• W2085455080 hasConcept C154317977 @default.
• W2085455080 hasConcept C1621761 @default.
• W2085455080 hasConcept C167672396 @default.
• W2085455080 hasConcept C187316574 @default.
• W2085455080 hasConcept C202751555 @default.
• W2085455080 hasConcept C203014093 @default.
• W2085455080 hasConcept C2776090121 @default.
• W2085455080 hasConcept C2776447464 @default.
• W2085455080 hasConcept C2778297628 @default.
• W2085455080 hasConcept C2778513237 @default.
• W2085455080 hasConcept C2778690821 @default.
• W2085455080 hasConcept C2780640218 @default.
• W2085455080 hasConcept C2781101188 @default.
• W2085455080 hasConcept C2781184567 @default.
• W2085455080 hasConcept C2781462264 @default.
• W2085455080 hasConcept C39347974 @default.
• W2085455080 hasConcept C553184892 @default.
• W2085455080 hasConcept C55493867 @default.
• W2085455080 hasConcept C71924100 @default.
• W2085455080 hasConcept C86803240 @default.
• W2085455080 hasConcept C8891405 @default.
• W2085455080 hasConceptScore W2085455080C114684123 @default.
• W2085455080 hasConceptScore W2085455080C154317977 @default.
• W2085455080 hasConceptScore W2085455080C1621761 @default.
• W2085455080 hasConceptScore W2085455080C167672396 @default.

• next