Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085462838> ?p ?o ?g. }
- W2085462838 endingPage "536" @default.
- W2085462838 startingPage "530" @default.
- W2085462838 abstract "The effects of several protein kinase activators and protein phosphatase inhibitors on the phenobarbital (PB)-induced gene expression of CYP2B1 and CYP2B2 (CYP2B1/2B2) in adult rat hepatocytes were investigated. Insulin, epidermal growth factor, interleukin 6, cAMP, phorbol 12-myristate 13-acetate, tumor necrosis factor α, vanadate, and okadaic acid were found to suppress the induction of CYP2B1/2B2 at mRNA and protein levels in hepatocytes. cAMP and vanadate completely suppressed the induction of CYP2B1/2B2 gene expression in both rat hepatocytes and liver. The addition of genistein to vanadate-treated hepatocytes partially recovered the induction of CYP2B1/2B1 gene expression by PB. These results of the present study demonstrate that phosphorylation/dephosphorylation steps are crucial for the induction of CYP2B1/2B2 gene expression by PB." @default.
- W2085462838 created "2016-06-24" @default.
- W2085462838 creator A5002041790 @default.
- W2085462838 creator A5006636847 @default.
- W2085462838 creator A5049472750 @default.
- W2085462838 creator A5051254462 @default.
- W2085462838 creator A5063683943 @default.
- W2085462838 date "1999-10-01" @default.
- W2085462838 modified "2023-10-18" @default.
- W2085462838 title "Phosphorylation/Dephosphorylation Steps Are Crucial for the Induction of CYP2B1 and CYP2B2 Gene Expression by Phenobarbital" @default.
- W2085462838 cites W1565303318 @default.
- W2085462838 cites W1573552069 @default.
- W2085462838 cites W1750807446 @default.
- W2085462838 cites W1922693149 @default.
- W2085462838 cites W1968307951 @default.
- W2085462838 cites W1975848409 @default.
- W2085462838 cites W1980544949 @default.
- W2085462838 cites W1990330754 @default.
- W2085462838 cites W1998342457 @default.
- W2085462838 cites W1999306914 @default.
- W2085462838 cites W1999901292 @default.
- W2085462838 cites W2007798461 @default.
- W2085462838 cites W2008323897 @default.
- W2085462838 cites W2016321423 @default.
- W2085462838 cites W2021654612 @default.
- W2085462838 cites W2024244127 @default.
- W2085462838 cites W2025063808 @default.
- W2085462838 cites W2025128734 @default.
- W2085462838 cites W2031223075 @default.
- W2085462838 cites W2041779532 @default.
- W2085462838 cites W2043337058 @default.
- W2085462838 cites W2056458409 @default.
- W2085462838 cites W2056988802 @default.
- W2085462838 cites W2066141169 @default.
- W2085462838 cites W2066475741 @default.
- W2085462838 cites W2072836362 @default.
- W2085462838 cites W2075943246 @default.
- W2085462838 cites W2085837116 @default.
- W2085462838 cites W2090641061 @default.
- W2085462838 cites W2114555447 @default.
- W2085462838 cites W2129322617 @default.
- W2085462838 cites W2135248587 @default.
- W2085462838 cites W2146909058 @default.
- W2085462838 cites W2149780895 @default.
- W2085462838 cites W2192686175 @default.
- W2085462838 cites W4294216491 @default.
- W2085462838 doi "https://doi.org/10.1006/bbrc.1999.1544" @default.
- W2085462838 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10529397" @default.
- W2085462838 hasPublicationYear "1999" @default.
- W2085462838 type Work @default.
- W2085462838 sameAs 2085462838 @default.
- W2085462838 citedByCount "36" @default.
- W2085462838 countsByYear W20854628382015 @default.
- W2085462838 countsByYear W20854628382016 @default.
- W2085462838 countsByYear W20854628382017 @default.
- W2085462838 countsByYear W20854628382020 @default.
- W2085462838 crossrefType "journal-article" @default.
- W2085462838 hasAuthorship W2085462838A5002041790 @default.
- W2085462838 hasAuthorship W2085462838A5006636847 @default.
- W2085462838 hasAuthorship W2085462838A5049472750 @default.
- W2085462838 hasAuthorship W2085462838A5051254462 @default.
- W2085462838 hasAuthorship W2085462838A5063683943 @default.
- W2085462838 hasConcept C104317684 @default.
- W2085462838 hasConcept C11960822 @default.
- W2085462838 hasConcept C134018914 @default.
- W2085462838 hasConcept C150194340 @default.
- W2085462838 hasConcept C153911025 @default.
- W2085462838 hasConcept C178666793 @default.
- W2085462838 hasConcept C181912034 @default.
- W2085462838 hasConcept C185592680 @default.
- W2085462838 hasConcept C2776953658 @default.
- W2085462838 hasConcept C2778793413 @default.
- W2085462838 hasConcept C2781116636 @default.
- W2085462838 hasConcept C55493867 @default.
- W2085462838 hasConcept C86803240 @default.
- W2085462838 hasConcept C95444343 @default.
- W2085462838 hasConceptScore W2085462838C104317684 @default.
- W2085462838 hasConceptScore W2085462838C11960822 @default.
- W2085462838 hasConceptScore W2085462838C134018914 @default.
- W2085462838 hasConceptScore W2085462838C150194340 @default.
- W2085462838 hasConceptScore W2085462838C153911025 @default.
- W2085462838 hasConceptScore W2085462838C178666793 @default.
- W2085462838 hasConceptScore W2085462838C181912034 @default.
- W2085462838 hasConceptScore W2085462838C185592680 @default.
- W2085462838 hasConceptScore W2085462838C2776953658 @default.
- W2085462838 hasConceptScore W2085462838C2778793413 @default.
- W2085462838 hasConceptScore W2085462838C2781116636 @default.
- W2085462838 hasConceptScore W2085462838C55493867 @default.
- W2085462838 hasConceptScore W2085462838C86803240 @default.
- W2085462838 hasConceptScore W2085462838C95444343 @default.
- W2085462838 hasIssue "2" @default.
- W2085462838 hasLocation W20854628381 @default.
- W2085462838 hasLocation W20854628382 @default.
- W2085462838 hasOpenAccess W2085462838 @default.
- W2085462838 hasPrimaryLocation W20854628381 @default.
- W2085462838 hasRelatedWork W1597904332 @default.
- W2085462838 hasRelatedWork W178460425 @default.
- W2085462838 hasRelatedWork W1972691843 @default.