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- W2085470511 endingPage "120" @default.
- W2085470511 startingPage "112" @default.
- W2085470511 abstract "The field of neuroimmunology is rapidly advancing. There is a growing appreciation for heterogeneity, both in inflammatory composition and region-specific inflammatory responses. This understanding underscores the importance of developing targeted immunomodulatory therapies for treating neurological disorders. Concerning neurotrauma, there is a dearth of publications directly comparing inflammatory responses in the brain and spinal cord after injury. The question therefore remains as to whether inflammatory cells responding to spinal cord vs. brain injury adopt similar functions and are therefore amenable to common therapies. In this review, we address this question while revisiting and modernizing the conclusions from publications that have directly compared inflammation across brain and spinal cord injuries. By examining molecular differences, anatomical variations, and inflammatory cell phenotypes between the injured brain and spinal cord, we provide insight into how neuroinflammation relates to neurotrauma and into fundamental differences between the brain and spinal cord." @default.
- W2085470511 created "2016-06-24" @default.
- W2085470511 creator A5043136033 @default.
- W2085470511 creator A5067922248 @default.
- W2085470511 date "2014-08-01" @default.
- W2085470511 modified "2023-09-27" @default.
- W2085470511 title "Is neuroinflammation in the injured spinal cord different than in the brain? Examining intrinsic differences between the brain and spinal cord" @default.
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