FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085474142> ?p ?o ?g. }

• W2085474142 endingPage "350" @default.
• W2085474142 startingPage "341" @default.
• W2085474142 abstract "The protection of cells expressing class I HLA molecules from NK lysis is mediated by natural killer cell inhibitory receptors (NKIR). Using site-directed mutagenesis, residues on HLA-C that determine the locus specificity (alphaVal-76), allotype group specificity (a dimorphism alphaAsn-80/Lys-80), and affinity of NKIR binding (a second pair of dimorphisms, alphaAla-73, Asp-90 or alphaThr-73, Ala-90) have been identified. Thus the footprint of the NKIR on the alpha1 helix of the class I MHC molecule HLA-C and its associated beta strands are similar in position to the site occupied by superantigens on and behind the alpha1 helix of the class II MHC molecule HLA-DR1, but further toward its C-terminus. The intermediate affinity binding of NKIR to HLA-C, determined by alpha73 and alpha90, has an essential role in preventing cross-reactivity and ensuring the availability of NK cells for immunosurveillance; low affinity and high affinity mutants are both physiologically impaired." @default.
• W2085474142 created "2016-06-24" @default.
• W2085474142 creator A5017875858 @default.
• W2085474142 creator A5029316334 @default.
• W2085474142 creator A5035583924 @default.
• W2085474142 creator A5040129865 @default.
• W2085474142 creator A5050580621 @default.
• W2085474142 creator A5086010689 @default.
• W2085474142 creator A5086116623 @default.
• W2085474142 date "1997-03-01" @default.
• W2085474142 modified "2023-10-14" @default.
• W2085474142 title "The Binding Site of NK Receptors on HLA-C Molecules" @default.
• W2085474142 cites W1548757996 @default.
• W2085474142 cites W1556867369 @default.
• W2085474142 cites W1966190880 @default.
• W2085474142 cites W1968046203 @default.
• W2085474142 cites W1968345966 @default.
• W2085474142 cites W1976805459 @default.
• W2085474142 cites W1990806106 @default.
• W2085474142 cites W1995134733 @default.
• W2085474142 cites W2005765588 @default.
• W2085474142 cites W2019135046 @default.
• W2085474142 cites W2024441858 @default.
• W2085474142 cites W2037133606 @default.
• W2085474142 cites W2038597389 @default.
• W2085474142 cites W2060095976 @default.
• W2085474142 cites W2064140853 @default.
• W2085474142 cites W2066053659 @default.
• W2085474142 cites W2070091724 @default.
• W2085474142 cites W2079786360 @default.
• W2085474142 cites W2079923162 @default.
• W2085474142 cites W2083393665 @default.
• W2085474142 cites W2088564222 @default.
• W2085474142 cites W2092952127 @default.
• W2085474142 cites W2098130458 @default.
• W2085474142 cites W2098734667 @default.
• W2085474142 cites W2102453705 @default.
• W2085474142 cites W2106241062 @default.
• W2085474142 cites W2106481565 @default.
• W2085474142 cites W2111441225 @default.
• W2085474142 cites W2118279329 @default.
• W2085474142 cites W2128673201 @default.
• W2085474142 cites W2133226508 @default.
• W2085474142 cites W2135733489 @default.
• W2085474142 cites W2146953988 @default.
• W2085474142 cites W2155740919 @default.
• W2085474142 cites W2161165126 @default.
• W2085474142 cites W2164753292 @default.
• W2085474142 cites W2318559441 @default.
• W2085474142 cites W4253085957 @default.
• W2085474142 doi "https://doi.org/10.1016/s1074-7613(00)80336-2" @default.
• W2085474142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9075934" @default.
• W2085474142 hasPublicationYear "1997" @default.
• W2085474142 type Work @default.
• W2085474142 sameAs 2085474142 @default.
• W2085474142 citedByCount "96" @default.
• W2085474142 countsByYear W20854741422012 @default.
• W2085474142 countsByYear W20854741422013 @default.
• W2085474142 countsByYear W20854741422015 @default.
• W2085474142 countsByYear W20854741422016 @default.
• W2085474142 countsByYear W20854741422017 @default.
• W2085474142 countsByYear W20854741422018 @default.
• W2085474142 countsByYear W20854741422019 @default.
• W2085474142 countsByYear W20854741422020 @default.
• W2085474142 countsByYear W20854741422023 @default.
• W2085474142 crossrefType "journal-article" @default.
• W2085474142 hasAuthorship W2085474142A5017875858 @default.
• W2085474142 hasAuthorship W2085474142A5029316334 @default.
• W2085474142 hasAuthorship W2085474142A5035583924 @default.
• W2085474142 hasAuthorship W2085474142A5040129865 @default.
• W2085474142 hasAuthorship W2085474142A5050580621 @default.
• W2085474142 hasAuthorship W2085474142A5086010689 @default.
• W2085474142 hasAuthorship W2085474142A5086116623 @default.
• W2085474142 hasBestOaLocation W20854741421 @default.
• W2085474142 hasConcept C107824862 @default.
• W2085474142 hasConcept C147483822 @default.
• W2085474142 hasConcept C153911025 @default.
• W2085474142 hasConcept C170493617 @default.
• W2085474142 hasConcept C170627219 @default.
• W2085474142 hasConcept C188280979 @default.
• W2085474142 hasConcept C203014093 @default.
• W2085474142 hasConcept C207936829 @default.
• W2085474142 hasConcept C2776885095 @default.
• W2085474142 hasConcept C2780889450 @default.
• W2085474142 hasConcept C54355233 @default.
• W2085474142 hasConcept C86803240 @default.
• W2085474142 hasConcept C8891405 @default.
• W2085474142 hasConcept C95444343 @default.
• W2085474142 hasConceptScore W2085474142C107824862 @default.
• W2085474142 hasConceptScore W2085474142C147483822 @default.
• W2085474142 hasConceptScore W2085474142C153911025 @default.
• W2085474142 hasConceptScore W2085474142C170493617 @default.
• W2085474142 hasConceptScore W2085474142C170627219 @default.
• W2085474142 hasConceptScore W2085474142C188280979 @default.
• W2085474142 hasConceptScore W2085474142C203014093 @default.
• W2085474142 hasConceptScore W2085474142C207936829 @default.
• W2085474142 hasConceptScore W2085474142C2776885095 @default.
• W2085474142 hasConceptScore W2085474142C2780889450 @default.

• next