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- W2085477560 endingPage "426" @default.
- W2085477560 startingPage "403" @default.
- W2085477560 abstract "Abstract Skeletal muscle is susceptible to oxidative deterioration due to a combination of lipid oxidation catalysts and membrane lipid systems that are high in unsaturated fatty acids. To prevent or delay oxidation reactions, several endogenous antioxidant systems are found in muscle tissue. These include α‐tocopherol, histidine‐containing dipeptides, and antioxidant enzymes such as glutathione peroxidase, superoxide dismutase, and catalase. The contribution of α‐tocopherol to the oxidative stability of skeletal muscle is largely influenced by diet. Dietary supplementation of tocopherol has been shown to increase muscle α‐tocopherol concentrations and inhibit both lipid oxidation and color deterioration. Dietary selenium supplementation has also been shown to increase the oxidative stability of muscle presumably by increasing the activity of glutathione peroxidase. The oxidative stability of skeletal muscle is also influenced by the histidine‐containing dipeptides, carnosine and anserine. Whereas carnosine and anserine are affected by diet less than α‐tocopherol and glutathione peroxidase, their concentrations vary widely with species and muscle type. In pigs, beef, and turkey muscle, carnosine concentrations are greater than anserine, while the opposite is true in rabbit, salmon, and chicken muscle. Anserine and carnosine are found in greater concentrations in muscle high in white fibers, with chicken white muscle containing over fivefold more anserine and carnosine than red muscle. Anserine and carnosine are thought to inhibit lipid oxidation by a combination of free radical scavenging and metal chelation." @default.
- W2085477560 created "2016-06-24" @default.
- W2085477560 creator A5020750356 @default.
- W2085477560 creator A5082097141 @default.
- W2085477560 date "1994-07-01" @default.
- W2085477560 modified "2023-10-16" @default.
- W2085477560 title "Endogenous skeletal muscle antioxidants" @default.
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