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- W2085488538 abstract "We measured inflammatory and neural markers of disease from 7 days to one year after induction of experimental autoimmune encephalomyelitis (EAE) by immunization with myelin oligodendrocyte glycoprotein (MOG) peptide. Axon loss began before behavioral signs when T cell infiltration and microglial activation were very subtle. Remyelination was only detectable ultrastructurally. Axon numbers in the dorsal column plateau around day 30 p.i. while behavioral measures (EAE scores, rotarod, grip strength) partially recover. These results provide a starting point for testing potential neuroprotective treatments for multiple sclerosis (MS)." @default.
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- W2085488538 date "2009-07-01" @default.
- W2085488538 modified "2023-09-27" @default.
- W2085488538 title "30. Altered affective behavior in a model of multiple sclerosis: Impact of neurotrophic factors" @default.
- W2085488538 doi "https://doi.org/10.1016/j.bbi.2009.05.033" @default.
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