FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085540286> ?p ?o ?g. }

• W2085540286 endingPage "1091" @default.
• W2085540286 startingPage "1081" @default.
• W2085540286 abstract "The use of ex vivo purging agents has shown to be beneficial for both allogeneic and autologous bone marrow transplantations. We have shown previously that spermine dialdehyde (SDA), an oxidized product of spermine, when used in phosphate-buffered saline (PBS) preferentially inhibits T-cell proliferation while sparing myeloid cells. Lethally irradiated mice were rescued by reconstitution with SDA-treated allogeneic marrow and showed no sign of graft-vs-host disease (GVHD). In this paper, we show by HPLC analysis that SDA degraded rapidly in PBS but remained intact in saline. Administered in saline, SDA was more inhibitory on leukemic cell lines than normal myeloid or T-cells. Lethally irradiated mice receiving a syngeneic bone marrow leukemic cell mixture treated ex vivo with SDA in saline did not manifest leukemia. Thus, the preferential inhibitory effect of SDA and its degraded products in different buffers suggest that SDA could act as a novel purging agent for both allogeneic and autologous bone marrow transplantations." @default.
• W2085540286 created "2016-06-24" @default.
• W2085540286 creator A5019918575 @default.
• W2085540286 creator A5025021965 @default.
• W2085540286 creator A5029399484 @default.
• W2085540286 creator A5030465549 @default.
• W2085540286 creator A5031906908 @default.
• W2085540286 creator A5043125092 @default.
• W2085540286 creator A5046116573 @default.
• W2085540286 date "1992-08-01" @default.
• W2085540286 modified "2023-09-27" @default.
• W2085540286 title "Spermine dialdehyde, a novel ex vivo purging agent for both allogeneic and autologous bone marrow transplantations" @default.
• W2085540286 cites W1558084593 @default.
• W2085540286 cites W1608480048 @default.
• W2085540286 cites W1676095416 @default.
• W2085540286 cites W1972480578 @default.
• W2085540286 cites W1973035870 @default.
• W2085540286 cites W1978107497 @default.
• W2085540286 cites W2019348584 @default.
• W2085540286 cites W2046395856 @default.
• W2085540286 cites W2047491480 @default.
• W2085540286 cites W2061600837 @default.
• W2085540286 cites W2064164050 @default.
• W2085540286 cites W2064374436 @default.
• W2085540286 cites W2069579949 @default.
• W2085540286 cites W2124798360 @default.
• W2085540286 cites W2133165855 @default.
• W2085540286 cites W2143354953 @default.
• W2085540286 cites W2144133225 @default.
• W2085540286 cites W2319334595 @default.
• W2085540286 cites W2407076429 @default.
• W2085540286 cites W2470373220 @default.
• W2085540286 doi "https://doi.org/10.1016/0192-0561(92)90153-c" @default.
• W2085540286 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1428363" @default.
• W2085540286 hasPublicationYear "1992" @default.
• W2085540286 type Work @default.
• W2085540286 sameAs 2085540286 @default.
• W2085540286 citedByCount "2" @default.
• W2085540286 crossrefType "journal-article" @default.
• W2085540286 hasAuthorship W2085540286A5019918575 @default.
• W2085540286 hasAuthorship W2085540286A5025021965 @default.
• W2085540286 hasAuthorship W2085540286A5029399484 @default.
• W2085540286 hasAuthorship W2085540286A5030465549 @default.
• W2085540286 hasAuthorship W2085540286A5031906908 @default.
• W2085540286 hasAuthorship W2085540286A5043125092 @default.
• W2085540286 hasAuthorship W2085540286A5046116573 @default.
• W2085540286 hasConcept C126322002 @default.
• W2085540286 hasConcept C141071460 @default.
• W2085540286 hasConcept C150903083 @default.
• W2085540286 hasConcept C181199279 @default.
• W2085540286 hasConcept C185592680 @default.
• W2085540286 hasConcept C203014093 @default.
• W2085540286 hasConcept C207001950 @default.
• W2085540286 hasConcept C26291073 @default.
• W2085540286 hasConcept C2776109719 @default.
• W2085540286 hasConcept C2777397205 @default.
• W2085540286 hasConcept C2778729363 @default.
• W2085540286 hasConcept C2779282312 @default.
• W2085540286 hasConcept C2780007613 @default.
• W2085540286 hasConcept C2911091166 @default.
• W2085540286 hasConcept C502942594 @default.
• W2085540286 hasConcept C55493867 @default.
• W2085540286 hasConcept C71924100 @default.
• W2085540286 hasConcept C86803240 @default.
• W2085540286 hasConceptScore W2085540286C126322002 @default.
• W2085540286 hasConceptScore W2085540286C141071460 @default.
• W2085540286 hasConceptScore W2085540286C150903083 @default.
• W2085540286 hasConceptScore W2085540286C181199279 @default.
• W2085540286 hasConceptScore W2085540286C185592680 @default.
• W2085540286 hasConceptScore W2085540286C203014093 @default.
• W2085540286 hasConceptScore W2085540286C207001950 @default.
• W2085540286 hasConceptScore W2085540286C26291073 @default.
• W2085540286 hasConceptScore W2085540286C2776109719 @default.
• W2085540286 hasConceptScore W2085540286C2777397205 @default.
• W2085540286 hasConceptScore W2085540286C2778729363 @default.
• W2085540286 hasConceptScore W2085540286C2779282312 @default.
• W2085540286 hasConceptScore W2085540286C2780007613 @default.
• W2085540286 hasConceptScore W2085540286C2911091166 @default.
• W2085540286 hasConceptScore W2085540286C502942594 @default.
• W2085540286 hasConceptScore W2085540286C55493867 @default.
• W2085540286 hasConceptScore W2085540286C71924100 @default.
• W2085540286 hasConceptScore W2085540286C86803240 @default.
• W2085540286 hasIssue "6" @default.
• W2085540286 hasLocation W20855402861 @default.
• W2085540286 hasLocation W20855402862 @default.
• W2085540286 hasOpenAccess W2085540286 @default.
• W2085540286 hasPrimaryLocation W20855402861 @default.
• W2085540286 hasRelatedWork W2037182962 @default.
• W2085540286 hasRelatedWork W2048893796 @default.
• W2085540286 hasRelatedWork W2053503674 @default.
• W2085540286 hasRelatedWork W2058153393 @default.
• W2085540286 hasRelatedWork W2079652418 @default.
• W2085540286 hasRelatedWork W2104683328 @default.
• W2085540286 hasRelatedWork W2140910281 @default.
• W2085540286 hasRelatedWork W3111154559 @default.
• W2085540286 hasRelatedWork W3162856407 @default.
• W2085540286 hasRelatedWork W42711520 @default.
• W2085540286 hasVolume "14" @default.

• next