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- W2085581611 abstract "1. In the present study, 1.39 kb of the renin gene 5' region in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats was amplified by polymerase chain reaction from genomic DNA and sequenced. Consistent differences in the renin gene sequence of SHR and WKY rats were found at positions -725, -727, -979 and -1126/-1129 as numbered from the transcription start site (+1). No polymorphism was specific to hypertensive rats. 2. Gel-shift assays were performed using labelled SHR renin promotor DNA and nuclear proteins extracted from rat kidneys. The regions between -1122 and -1139 and between -701 and -797 showed protein binding." @default.
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- W2085581611 date "2001-01-01" @default.
- W2085581611 modified "2023-09-24" @default.
- W2085581611 title "Polymorphisms Of The Renin Gene Promoter In Spontaneously Hypertensive And Wistar-Kyoto Rats" @default.
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- W2085581611 doi "https://doi.org/10.1046/j.1440-1681.2001.03397.x" @default.
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