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- W2085586990 abstract "The presence of vitamin A in the medium results in a large increase in β-carotene content in wildtype Phycomyces blakesleeanus; in carB mutants, which accumulate phytoene, and carR mutants, which accumulate lycopene, the presence of vitamin A results in an increase in these intermediates. In carA mutants, which usually form no carotenoids, vitamin A partially counteracts the mutational block and allows β-carotene synthesis. Vitamin A is not itself converted to β-carotene. β-Ionone, long known as a stimulator of carotenogenesis, can also counteract carA mutations. The effects of vitamin A and β-ionone do not occur in the presence of the protein-synthesis inhibitor cycloheximide. Vitamin A and β-ionone stimulate carotenogenesis through the normal pathway, probably by interaction with the carA gene product." @default.
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- W2085586990 date "1974-10-01" @default.
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- W2085586990 title "Regulation of Carotene Biosynthesis in Phycomyces by Vitamin A and beta-Ionone" @default.
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