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- W2085605412 abstract "A prospective study was performed on 30 men with asymptomatic, recurrent urinary tract infections in order to assess contemporary treatment of this disease. Patients had to have significant bacteriuria with a pure culture of Pseudomonas aeruginosa or a member of the Enterobacteriaceae family that was susceptible in vitro to the antimicrobial agent prescribed, and a urinary sediment that demonstrated a positive antibody-coated bacteria immunofluorescence test of at least 2+ intensity. All patients were subjected to excretory urograms. Therapeutic response was appraised in accordance with previously issued FDA protocol guidelines. Colonial morphology, biochemical tests, antimicrobial susceptibility testing and serotyping of the E coli isolates and pyocin typing of Pseudomonas aeruginosa were the methods used to differentiate bacterial relapse, a measure of drug ineptitude, from reinfection, a measure of inadequate host defenses. Sterility of the urine for a minimum of six weeks after therapy developed in only 29% of the patients who could complete the two-week course of therapy. Bacterial relapse, the prevalent form of recurrence, could not be explained by the isolation of cell wall-defective bacteria, rapid emergence of resistant mutants or inadequately treated chronic bacterial prostatitis. The customary practice of prescribing a two-week course of therapy to men with recurrent, invasive urinary tract infections falls far short of the desired treatment goal." @default.
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- W2085605412 date "1980-01-01" @default.
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- W2085605412 title "Recurrent urinary tract infections in men: an assessment of contemporary treatment" @default.
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- W2085605412 doi "https://doi.org/10.1097/00000441-198001000-00004" @default.
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