FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085654600> ?p ?o ?g. }

• W2085654600 endingPage "1762" @default.
• W2085654600 startingPage "1754" @default.
• W2085654600 abstract "Recent studies implicating dendritic protein synthesis in synaptic plasticity have focused attention on identifying components of the molecular machinery involved in processing dendritic RNA. Although Translin was originally identified as a protein capable of binding single-stranded DNA, subsequent studies have demonstrated that it also binds RNA in vitro. Because previous studies indicated that Translin-containing RNA/single-stranded DNA binding complexes are highly enriched in brain, we and others have proposed that it may be involved in dendritic RNA processing. To assess this possibility, we have conducted studies aimed at defining the localization of Translin and its partner protein, Trax, in brain. In situ hybridization studies demonstrated that both Translin and Trax are expressed in neurons with prominent staining apparent in cerebellar Purkinje cells and neuronal layers of the hippocampus. Subcellular fractionation studies demonstrated that both Translin and Trax are highly enriched in the cytoplasmic fraction compared with nuclear extracts. Furthermore, immunohistochemical studies with Translin antibodies revealed prominent staining in Purkinje neuron cell bodies that extends into proximal and distal dendrites. A similar pattern of somatodendritic localization was observed in hippocampal and neocortical pyramidal neurons. These findings demonstrate that Translin is expressed in neuronal dendrites and therefore support the hypothesis that the Translin/Trax complex may be involved in dendritic RNA processing." @default.
• W2085654600 created "2016-06-24" @default.
• W2085654600 creator A5057464730 @default.
• W2085654600 creator A5058219081 @default.
• W2085654600 creator A5063758857 @default.
• W2085654600 creator A5065869401 @default.
• W2085654600 creator A5081054293 @default.
• W2085654600 creator A5086345193 @default.
• W2085654600 date "2002-01-04" @default.
• W2085654600 modified "2023-10-13" @default.
• W2085654600 title "Somatodendritic Localization of Translin, a Component of the Translin/Trax RNA Binding Complex" @default.
• W2085654600 cites W1501571963 @default.
• W2085654600 cites W1918118064 @default.
• W2085654600 cites W1964695319 @default.
• W2085654600 cites W1970409943 @default.
• W2085654600 cites W1973309638 @default.
• W2085654600 cites W1977782896 @default.
• W2085654600 cites W1979496428 @default.
• W2085654600 cites W1987030209 @default.
• W2085654600 cites W1987633417 @default.
• W2085654600 cites W2007558376 @default.
• W2085654600 cites W2014090388 @default.
• W2085654600 cites W2014846478 @default.
• W2085654600 cites W2020784504 @default.
• W2085654600 cites W2026998769 @default.
• W2085654600 cites W2037859334 @default.
• W2085654600 cites W2045095291 @default.
• W2085654600 cites W2049479116 @default.
• W2085654600 cites W2051918196 @default.
• W2085654600 cites W2052626337 @default.
• W2085654600 cites W2056555295 @default.
• W2085654600 cites W2077857663 @default.
• W2085654600 cites W2082079131 @default.
• W2085654600 cites W2094898557 @default.
• W2085654600 cites W2095262908 @default.
• W2085654600 cites W2095832516 @default.
• W2085654600 cites W2113825887 @default.
• W2085654600 cites W2137433892 @default.
• W2085654600 cites W2142213647 @default.
• W2085654600 cites W2145949628 @default.
• W2085654600 cites W2160769038 @default.
• W2085654600 cites W2443951218 @default.
• W2085654600 doi "https://doi.org/10.1046/j.1471-4159.2000.0751754.x" @default.
• W2085654600 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10987859" @default.
• W2085654600 hasPublicationYear "2002" @default.
• W2085654600 type Work @default.
• W2085654600 sameAs 2085654600 @default.
• W2085654600 citedByCount "59" @default.
• W2085654600 countsByYear W20856546002012 @default.
• W2085654600 countsByYear W20856546002013 @default.
• W2085654600 countsByYear W20856546002014 @default.
• W2085654600 countsByYear W20856546002015 @default.
• W2085654600 countsByYear W20856546002016 @default.
• W2085654600 countsByYear W20856546002017 @default.
• W2085654600 countsByYear W20856546002018 @default.
• W2085654600 countsByYear W20856546002019 @default.
• W2085654600 countsByYear W20856546002020 @default.
• W2085654600 countsByYear W20856546002022 @default.
• W2085654600 countsByYear W20856546002023 @default.
• W2085654600 crossrefType "journal-article" @default.
• W2085654600 hasAuthorship W2085654600A5057464730 @default.
• W2085654600 hasAuthorship W2085654600A5058219081 @default.
• W2085654600 hasAuthorship W2085654600A5063758857 @default.
• W2085654600 hasAuthorship W2085654600A5065869401 @default.
• W2085654600 hasAuthorship W2085654600A5081054293 @default.
• W2085654600 hasAuthorship W2085654600A5086345193 @default.
• W2085654600 hasConcept C104317684 @default.
• W2085654600 hasConcept C142724271 @default.
• W2085654600 hasConcept C148762608 @default.
• W2085654600 hasConcept C153911025 @default.
• W2085654600 hasConcept C169760540 @default.
• W2085654600 hasConcept C2776925932 @default.
• W2085654600 hasConcept C2779134260 @default.
• W2085654600 hasConcept C41282012 @default.
• W2085654600 hasConcept C55493867 @default.
• W2085654600 hasConcept C67705224 @default.
• W2085654600 hasConcept C71924100 @default.
• W2085654600 hasConcept C86803240 @default.
• W2085654600 hasConcept C95444343 @default.
• W2085654600 hasConceptScore W2085654600C104317684 @default.
• W2085654600 hasConceptScore W2085654600C142724271 @default.
• W2085654600 hasConceptScore W2085654600C148762608 @default.
• W2085654600 hasConceptScore W2085654600C153911025 @default.
• W2085654600 hasConceptScore W2085654600C169760540 @default.
• W2085654600 hasConceptScore W2085654600C2776925932 @default.
• W2085654600 hasConceptScore W2085654600C2779134260 @default.
• W2085654600 hasConceptScore W2085654600C41282012 @default.
• W2085654600 hasConceptScore W2085654600C55493867 @default.
• W2085654600 hasConceptScore W2085654600C67705224 @default.
• W2085654600 hasConceptScore W2085654600C71924100 @default.
• W2085654600 hasConceptScore W2085654600C86803240 @default.
• W2085654600 hasConceptScore W2085654600C95444343 @default.
• W2085654600 hasIssue "4" @default.
• W2085654600 hasLocation W20856546001 @default.
• W2085654600 hasLocation W20856546002 @default.
• W2085654600 hasOpenAccess W2085654600 @default.
• W2085654600 hasPrimaryLocation W20856546001 @default.
• W2085654600 hasRelatedWork W1886844647 @default.

• next