Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085672570> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2085672570 endingPage "109" @default.
- W2085672570 startingPage "105" @default.
- W2085672570 abstract "Sulfur mustard (bis(2-chloroethyl)sulfide; CAS: 505-60-2; abbreviated as HD) is a chemical warfare agent with not well understood mechanism of toxic effect. Deprivation of energy in cells and arising of oxidative stress appears during the exposure. Our experiment is based on investigation of 10 mg or 20 mg epigallocatechin gallate (EGCG) dose prophylactic effect (1 h before HD) in rats exposed to either 20 mg or 80 mg of HD. Blood mass, plasma and liver were sampled. Ferric reducing antioxidant power (FRAP), reduced glutathione, thiobarbuturic acid reactive substances (TBARSs), glutathione reductase, glutathione S-transferase and caspase 3 were assessed. Animals were sacrificed one day after exposure. We found significant deprivation of low molecular weight antioxidants due to EGCG but not due to HD. However, HD depleted reduced glutathione. EGCG has no effect to influence TBARS level. EGCG and HD up-regulated glutathione reductase and EGCG down regulated glutathione S-transferase in liver tissue. Regarding caspase, EGCG had anti apoptotic potency. We discuss potency to use EGCG to ameliorate redox balance after HD exposure. The data also appoints at difficulty in antioxidant therapy as prophylaxis to the oxidative stress related toxins exposure and ambivalent modulation of oxidative stress." @default.
- W2085672570 created "2016-06-24" @default.
- W2085672570 creator A5014941229 @default.
- W2085672570 creator A5073308601 @default.
- W2085672570 creator A5078050917 @default.
- W2085672570 date "2011-03-01" @default.
- W2085672570 modified "2023-10-18" @default.
- W2085672570 title "Sulfur mustard induced oxidative stress and its alteration by epigallocatechin gallate" @default.
- W2085672570 cites W1590592584 @default.
- W2085672570 cites W1966762585 @default.
- W2085672570 cites W1976485221 @default.
- W2085672570 cites W2008631464 @default.
- W2085672570 cites W2014165791 @default.
- W2085672570 cites W2028991215 @default.
- W2085672570 cites W2036042968 @default.
- W2085672570 cites W2073716990 @default.
- W2085672570 cites W2074726387 @default.
- W2085672570 cites W2080338197 @default.
- W2085672570 cites W2095116524 @default.
- W2085672570 cites W2096997867 @default.
- W2085672570 cites W2097628508 @default.
- W2085672570 cites W2127390105 @default.
- W2085672570 cites W2129770251 @default.
- W2085672570 cites W2139369955 @default.
- W2085672570 cites W2153635377 @default.
- W2085672570 cites W2153663340 @default.
- W2085672570 doi "https://doi.org/10.1016/j.toxlet.2010.12.011" @default.
- W2085672570 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21172412" @default.
- W2085672570 hasPublicationYear "2011" @default.
- W2085672570 type Work @default.
- W2085672570 sameAs 2085672570 @default.
- W2085672570 citedByCount "30" @default.
- W2085672570 countsByYear W20856725702012 @default.
- W2085672570 countsByYear W20856725702013 @default.
- W2085672570 countsByYear W20856725702014 @default.
- W2085672570 countsByYear W20856725702015 @default.
- W2085672570 countsByYear W20856725702016 @default.
- W2085672570 countsByYear W20856725702017 @default.
- W2085672570 countsByYear W20856725702018 @default.
- W2085672570 countsByYear W20856725702019 @default.
- W2085672570 countsByYear W20856725702020 @default.
- W2085672570 countsByYear W20856725702021 @default.
- W2085672570 crossrefType "journal-article" @default.
- W2085672570 hasAuthorship W2085672570A5014941229 @default.
- W2085672570 hasAuthorship W2085672570A5073308601 @default.
- W2085672570 hasAuthorship W2085672570A5078050917 @default.
- W2085672570 hasConcept C165069038 @default.
- W2085672570 hasConcept C178790620 @default.
- W2085672570 hasConcept C181199279 @default.
- W2085672570 hasConcept C185592680 @default.
- W2085672570 hasConcept C2776151105 @default.
- W2085672570 hasConcept C2777352226 @default.
- W2085672570 hasConcept C2778004101 @default.
- W2085672570 hasConcept C2778760513 @default.
- W2085672570 hasConcept C2780644109 @default.
- W2085672570 hasConcept C29730261 @default.
- W2085672570 hasConcept C538909803 @default.
- W2085672570 hasConcept C55493867 @default.
- W2085672570 hasConcept C86803240 @default.
- W2085672570 hasConcept C98274493 @default.
- W2085672570 hasConceptScore W2085672570C165069038 @default.
- W2085672570 hasConceptScore W2085672570C178790620 @default.
- W2085672570 hasConceptScore W2085672570C181199279 @default.
- W2085672570 hasConceptScore W2085672570C185592680 @default.
- W2085672570 hasConceptScore W2085672570C2776151105 @default.
- W2085672570 hasConceptScore W2085672570C2777352226 @default.
- W2085672570 hasConceptScore W2085672570C2778004101 @default.
- W2085672570 hasConceptScore W2085672570C2778760513 @default.
- W2085672570 hasConceptScore W2085672570C2780644109 @default.
- W2085672570 hasConceptScore W2085672570C29730261 @default.
- W2085672570 hasConceptScore W2085672570C538909803 @default.
- W2085672570 hasConceptScore W2085672570C55493867 @default.
- W2085672570 hasConceptScore W2085672570C86803240 @default.
- W2085672570 hasConceptScore W2085672570C98274493 @default.
- W2085672570 hasIssue "2" @default.
- W2085672570 hasLocation W20856725701 @default.
- W2085672570 hasLocation W20856725702 @default.
- W2085672570 hasOpenAccess W2085672570 @default.
- W2085672570 hasPrimaryLocation W20856725701 @default.
- W2085672570 hasRelatedWork W1988047489 @default.
- W2085672570 hasRelatedWork W1989911237 @default.
- W2085672570 hasRelatedWork W1992181654 @default.
- W2085672570 hasRelatedWork W2085672570 @default.
- W2085672570 hasRelatedWork W2103558449 @default.
- W2085672570 hasRelatedWork W2181600100 @default.
- W2085672570 hasRelatedWork W2223331562 @default.
- W2085672570 hasRelatedWork W2793794267 @default.
- W2085672570 hasRelatedWork W2913678864 @default.
- W2085672570 hasRelatedWork W4309491691 @default.
- W2085672570 hasVolume "201" @default.
- W2085672570 isParatext "false" @default.
- W2085672570 isRetracted "false" @default.
- W2085672570 magId "2085672570" @default.
- W2085672570 workType "article" @default.