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- W2085672847 abstract "We have analysed the kinetoplast DNA (kDNA) of Trypanosoma mega for the presence of DNA circles other than mini-circles and mini-circle oligomers. Degradation of networks with restriction endonucleases EcoRI, HhaI or PstI or S 1 nuclease yields minor bands on gels, in addition to the mini-circle bands. The combined molecular weight of the minor bands is 15–17 × 10 6 . Electron micrographs of kinetoplast DNA spread in a protein monolayer contain occasional circles longer than 3 μm. The majority class of these circles has a contour length corresponding to a mass of 16.1 × 10 6 D. We conclude that these maxi-circles, catenated into mini-circle networks, are an essential component of intact kinetoplast DNA of Trypanosoma mega ." @default.
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- W2085672847 date "1977-11-01" @default.
- W2085672847 modified "2023-09-27" @default.
- W2085672847 title "Maxi-circles in the kinetoplast DNA of Trypanosoma mega" @default.
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- W2085672847 doi "https://doi.org/10.1016/0014-4827(77)90283-x" @default.
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