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- W2085690212 abstract "You have accessJournal of UrologyInfections/Inflammation of the Genitourinary Tract: Kidney & Bladder I1 Apr 2015PD8-04 TRANSMOGRIFYING INFECTION STONES: ARE CALCIUM STONES NOW THE COMMONER INFECTION STONES IN PCNL? Ivo Dukic, Ayo Kalejaiye, Kim Jacobson, Francis Keeley, Anthony Timoney, and Joe Philip Ivo DukicIvo Dukic More articles by this author , Ayo KalejaiyeAyo Kalejaiye More articles by this author , Kim JacobsonKim Jacobson More articles by this author , Francis KeeleyFrancis Keeley More articles by this author , Anthony TimoneyAnthony Timoney More articles by this author , and Joe PhilipJoe Philip More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.919AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Percutaneous nephrolithotomy (PCNL) is the standard surgical treatment for large renal calculi. A preponderance for struvite stones have been reported but with significant regional variations. This study reviewed the stone composition in patients undergoing PCNL and the associated infection parameters. METHODS Over a two-year period ending October 2014, microbiological [mid-stream urine (MSU) and stone cultures] and biochemical (stone analysis) parameters for all patients undergoing PCNL were assessed in comparison to the number of septic episodes and length of stay. RESULTS 93 PCNL procedures were performed with 2/3rds having a positive stone culture (SC) and a quarter having had post-operative septic episodes. 62% SC positive patients had predominately calcium phosphate stones, 18% calcium oxalate stones and 21% rare stone types. In SC negative patients, 38% had calcium phosphate stones, 41% calcium oxalate stones and 27% rare stone types. Among the SC positive patients with calcium phosphate stones, 29% of patients had a febrile episode. In those with calcium oxalate, 45% had a febrile episode. The most common type of stone culture bacteria were mainly mixed growths (26%), E. coli (20%), and staphylococcus (15%) There was a 63% concordance between the pre-operative MSU and stone culture positive stones. CONCLUSIONS 80% of the patients had a calcium stone, with two thirds having a stone colonised with bacteria. A positive MSU and stone culture were associated with increased risks of sepsis. A high incidence of infected calcium stones and febrile episodes suggests changing patient stone demographics. Early identification of these patients should enable pre-emptive antibiotic therapy, thereby reducing septic episodes. © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e191 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ivo Dukic More articles by this author Ayo Kalejaiye More articles by this author Kim Jacobson More articles by this author Francis Keeley More articles by this author Anthony Timoney More articles by this author Joe Philip More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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- W2085690212 date "2015-04-01" @default.
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- W2085690212 title "PD8-04 TRANSMOGRIFYING INFECTION STONES: ARE CALCIUM STONES NOW THE COMMONER INFECTION STONES IN PCNL?" @default.
- W2085690212 doi "https://doi.org/10.1016/j.juro.2015.02.919" @default.
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