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- W208571303 abstract "Objective:To reveal the influence of electro-acupuncture (EA) at ‘Zusanli’ on the apoptosis of thymocytes in rats with sepsis. Methods: 40 SD rats were randomly divided into four groups. The sepsis model is made from abdominal infection resulted from cecal ligation and puncture(CLP), and then electro-acupuncture was given at ‘Zusanli’.The apoptosis of thymocytes was observed and the level of vasoactive intestinal peptide(VIP) in the pituitary gland and peripheral blood were determined by radioimmunoassay. Results: Sepsis induced by abdominal infection resulted from CLP can signifi cantly increase the apoptosis of thymocytes. Apoptosis rates of thymocytes in sepsis model group, non-acupoint group and ‘Zusanli’ group were all significantly higher than control group(P0.05).And apoptosis rate of thymocytes in ‘Zusanli’ group was significantly lower than those in sepsis model group and non-acupoint group(P0.05). Sepsis induced by abdominal infection resulted from CLP can reduce the level of VIP in the pituitary gland. The level of VIP in the pituitary gland and peripheral blood in model group, non-acupoint group and ‘Zusanli’ group were all significantly lower than control group(P0.05).The level of VIP in the pituitary and peripheral blood in ‘Zusanli’ group was significantly higher than those in model group and non-acupoint group(P0.05). Conclusions: EA at ‘Zusanli’ can significantly reduce the apoptosis lymphocytes in thymus in rats with sepsis resulted from CLP and that may be closely associated with the increased synthesis and release of VIP in pituitary gland and peripheral blood." @default.
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- W208571303 date "2009-01-01" @default.
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- W208571303 title "Effects of electro-acupuncture at 'Zusanli' on the apoptosis of thymocytes in rats with sepsis." @default.
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