FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085751427> ?p ?o ?g. }

• W2085751427 endingPage "1038" @default.
• W2085751427 startingPage "1031" @default.
• W2085751427 abstract "We examined the cytotoxic potential of nine N-[2-substituted-2-(2-thienyl)ethyl] piperazinyl quinolone derivatives on human oral epithelial mouth carcinoma (KB) and human squamous carcinoma (A431) cell lines. Phototoxic properties of these compounds were also evaluated by mouse 3T3 fibroblast under ultraviolet-A (UVA) irradiation. The percent of cell viability was evaluated by MTT assay. Compound 6 having a 4-[2-(phenylmethoxyimino)-2-(2-thienyl)ethyl] group attached to N4 position of piperazine ring of enoxacin showed the highest cytotoxicity potential on both A431 and KB cell lines (IC50 of 3.11+/-0.52 and 4.91+/-1.94 microg/ml, respectively). While some of the other tested compounds exhibited clear phototoxic potential in 3T3 cell line, compound 6 showed only a minor potential of phototoxicity. These findings suggest the high potential of 4-[2-(phenylmethoxyimino)-2-(2-thienyl)ethyl] derivative of enoxacin as a cytotoxic compound with low potency of phototoxic reactions. The mentioned chemical was identified to be of special interest for further characterization." @default.
• W2085751427 created "2016-06-24" @default.
• W2085751427 creator A5008519182 @default.
• W2085751427 creator A5010172433 @default.
• W2085751427 creator A5052554971 @default.
• W2085751427 creator A5062148422 @default.
• W2085751427 creator A5066494922 @default.
• W2085751427 date "2007-09-01" @default.
• W2085751427 modified "2023-09-27" @default.
• W2085751427 title "In vitro cytotoxicity and phototoxicity of N-piperazinyl quinolone derivatives with a 2-thienyl group" @default.
• W2085751427 cites W1978498929 @default.
• W2085751427 cites W1988031730 @default.
• W2085751427 cites W1988199149 @default.
• W2085751427 cites W1992292321 @default.
• W2085751427 cites W1993273298 @default.
• W2085751427 cites W1993515016 @default.
• W2085751427 cites W2007044831 @default.
• W2085751427 cites W2007570219 @default.
• W2085751427 cites W2015417856 @default.
• W2085751427 cites W2022020063 @default.
• W2085751427 cites W2024108968 @default.
• W2085751427 cites W2030740858 @default.
• W2085751427 cites W2036056435 @default.
• W2085751427 cites W2041141854 @default.
• W2085751427 cites W2052467184 @default.
• W2085751427 cites W2056248732 @default.
• W2085751427 cites W2058333442 @default.
• W2085751427 cites W2070302645 @default.
• W2085751427 cites W2073130730 @default.
• W2085751427 cites W2083756784 @default.
• W2085751427 cites W2086362429 @default.
• W2085751427 cites W2088526776 @default.
• W2085751427 cites W2105845560 @default.
• W2085751427 cites W2109201263 @default.
• W2085751427 cites W2116505575 @default.
• W2085751427 cites W2119360374 @default.
• W2085751427 cites W2138263364 @default.
• W2085751427 cites W2140907764 @default.
• W2085751427 cites W2156291973 @default.
• W2085751427 cites W2158728493 @default.
• W2085751427 cites W2160474604 @default.
• W2085751427 cites W2169031041 @default.
• W2085751427 cites W2169319168 @default.
• W2085751427 cites W2177795386 @default.
• W2085751427 doi "https://doi.org/10.1016/j.tiv.2007.03.011" @default.
• W2085751427 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17507195" @default.
• W2085751427 hasPublicationYear "2007" @default.
• W2085751427 type Work @default.
• W2085751427 sameAs 2085751427 @default.
• W2085751427 citedByCount "6" @default.
• W2085751427 countsByYear W20857514272013 @default.
• W2085751427 countsByYear W20857514272015 @default.
• W2085751427 countsByYear W20857514272019 @default.
• W2085751427 crossrefType "journal-article" @default.
• W2085751427 hasAuthorship W2085751427A5008519182 @default.
• W2085751427 hasAuthorship W2085751427A5010172433 @default.
• W2085751427 hasAuthorship W2085751427A5052554971 @default.
• W2085751427 hasAuthorship W2085751427A5062148422 @default.
• W2085751427 hasAuthorship W2085751427A5066494922 @default.
• W2085751427 hasConcept C109316439 @default.
• W2085751427 hasConcept C1491633281 @default.
• W2085751427 hasConcept C178790620 @default.
• W2085751427 hasConcept C185592680 @default.
• W2085751427 hasConcept C202751555 @default.
• W2085751427 hasConcept C20639190 @default.
• W2085751427 hasConcept C2776072828 @default.
• W2085751427 hasConcept C2776201271 @default.
• W2085751427 hasConcept C2777366897 @default.
• W2085751427 hasConcept C2777546739 @default.
• W2085751427 hasConcept C2778512257 @default.
• W2085751427 hasConcept C2778746504 @default.
• W2085751427 hasConcept C2779922871 @default.
• W2085751427 hasConcept C2780783641 @default.
• W2085751427 hasConcept C29537977 @default.
• W2085751427 hasConcept C2994460389 @default.
• W2085751427 hasConcept C47170353 @default.
• W2085751427 hasConcept C501593827 @default.
• W2085751427 hasConcept C54355233 @default.
• W2085751427 hasConcept C55493867 @default.
• W2085751427 hasConcept C67082663 @default.
• W2085751427 hasConcept C71240020 @default.
• W2085751427 hasConcept C81885089 @default.
• W2085751427 hasConcept C86803240 @default.
• W2085751427 hasConceptScore W2085751427C109316439 @default.
• W2085751427 hasConceptScore W2085751427C1491633281 @default.
• W2085751427 hasConceptScore W2085751427C178790620 @default.
• W2085751427 hasConceptScore W2085751427C185592680 @default.
• W2085751427 hasConceptScore W2085751427C202751555 @default.
• W2085751427 hasConceptScore W2085751427C20639190 @default.
• W2085751427 hasConceptScore W2085751427C2776072828 @default.
• W2085751427 hasConceptScore W2085751427C2776201271 @default.
• W2085751427 hasConceptScore W2085751427C2777366897 @default.
• W2085751427 hasConceptScore W2085751427C2777546739 @default.
• W2085751427 hasConceptScore W2085751427C2778512257 @default.
• W2085751427 hasConceptScore W2085751427C2778746504 @default.
• W2085751427 hasConceptScore W2085751427C2779922871 @default.
• W2085751427 hasConceptScore W2085751427C2780783641 @default.
• W2085751427 hasConceptScore W2085751427C29537977 @default.

• next