FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085755562> ?p ?o ?g. }

• W2085755562 endingPage "218" @default.
• W2085755562 startingPage "211" @default.
• W2085755562 abstract "Lung membranes are susceptible to oxygen radicals, formed during inflammation, redox cycling of toxic agents, exposition to ozon etc. Oxygen radicals may modify the beta-adrenergic response. However, at the same time beta-adrenoceptors of the lung are frequently addressed in therapy. We embarked upon this problem by studying the effects of the aldehyde 4-hydroxy-2,3-transnonenal (HNE), one of the major products of lipid peroxidation, on the density of beta-adrenoceptors of rat lung membranes. It is shown, that the physiological important sulfhydryl blocking agent HNE inactivates the beta-adrenoceptors in a time- and concentration dependent (0.5-2.5 mM) way, indicated by a decrease in (-)-[3H]dihydroalprenolol (DHA) binding to lung membranes. Moreover, it is shown that combined treatment of HNE with (-)-isoproterenol (0.5 microM) or 1-alprenolol (0.5-10 nM) does not influence the extent of inactivation of beta-adrenoceptors by HNE. This is in contrast with previous studies, conducted with other, synthetic, sulfhydryl blocking agents, such as N-ethylmaleimide (NEM), suggesting that an other mechanism of inactivation is involved upon HNE treatment." @default.
• W2085755562 created "2016-06-24" @default.
• W2085755562 creator A5052558608 @default.
• W2085755562 creator A5068604572 @default.
• W2085755562 creator A5084729994 @default.
• W2085755562 creator A5087896916 @default.
• W2085755562 creator A5091179262 @default.
• W2085755562 date "1986-01-01" @default.
• W2085755562 modified "2023-09-27" @default.
• W2085755562 title "The effects of 4-hydroxy-2,3-trans-nonenal on β-adrenoceptors of rat lung membranes" @default.
• W2085755562 cites W1541126435 @default.
• W2085755562 cites W1775749144 @default.
• W2085755562 cites W1970016508 @default.
• W2085755562 cites W1978896699 @default.
• W2085755562 cites W1996171860 @default.
• W2085755562 cites W2001712555 @default.
• W2085755562 cites W2007332607 @default.
• W2085755562 cites W2011669886 @default.
• W2085755562 cites W2043813981 @default.
• W2085755562 cites W2058008954 @default.
• W2085755562 cites W2075766904 @default.
• W2085755562 cites W2080036442 @default.
• W2085755562 cites W2080394861 @default.
• W2085755562 cites W2159597833 @default.
• W2085755562 cites W2413276709 @default.
• W2085755562 doi "https://doi.org/10.1016/s0009-2797(86)80067-9" @default.
• W2085755562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3021348" @default.
• W2085755562 hasPublicationYear "1986" @default.
• W2085755562 type Work @default.
• W2085755562 sameAs 2085755562 @default.
• W2085755562 citedByCount "19" @default.
• W2085755562 crossrefType "journal-article" @default.
• W2085755562 hasAuthorship W2085755562A5052558608 @default.
• W2085755562 hasAuthorship W2085755562A5068604572 @default.
• W2085755562 hasAuthorship W2085755562A5084729994 @default.
• W2085755562 hasAuthorship W2085755562A5087896916 @default.
• W2085755562 hasAuthorship W2085755562A5091179262 @default.
• W2085755562 hasConcept C12554922 @default.
• W2085755562 hasConcept C126322002 @default.
• W2085755562 hasConcept C139066938 @default.
• W2085755562 hasConcept C170493617 @default.
• W2085755562 hasConcept C178790620 @default.
• W2085755562 hasConcept C185592680 @default.
• W2085755562 hasConcept C199360897 @default.
• W2085755562 hasConcept C2776151105 @default.
• W2085755562 hasConcept C2776174256 @default.
• W2085755562 hasConcept C2776885963 @default.
• W2085755562 hasConcept C2777714996 @default.
• W2085755562 hasConcept C2778438532 @default.
• W2085755562 hasConcept C2780275434 @default.
• W2085755562 hasConcept C2780829032 @default.
• W2085755562 hasConcept C40465926 @default.
• W2085755562 hasConcept C41008148 @default.
• W2085755562 hasConcept C41625074 @default.
• W2085755562 hasConcept C540031477 @default.
• W2085755562 hasConcept C55493867 @default.
• W2085755562 hasConcept C58732023 @default.
• W2085755562 hasConcept C71240020 @default.
• W2085755562 hasConcept C71924100 @default.
• W2085755562 hasConcept C86803240 @default.
• W2085755562 hasConcept C98274493 @default.
• W2085755562 hasConceptScore W2085755562C12554922 @default.
• W2085755562 hasConceptScore W2085755562C126322002 @default.
• W2085755562 hasConceptScore W2085755562C139066938 @default.
• W2085755562 hasConceptScore W2085755562C170493617 @default.
• W2085755562 hasConceptScore W2085755562C178790620 @default.
• W2085755562 hasConceptScore W2085755562C185592680 @default.
• W2085755562 hasConceptScore W2085755562C199360897 @default.
• W2085755562 hasConceptScore W2085755562C2776151105 @default.
• W2085755562 hasConceptScore W2085755562C2776174256 @default.
• W2085755562 hasConceptScore W2085755562C2776885963 @default.
• W2085755562 hasConceptScore W2085755562C2777714996 @default.
• W2085755562 hasConceptScore W2085755562C2778438532 @default.
• W2085755562 hasConceptScore W2085755562C2780275434 @default.
• W2085755562 hasConceptScore W2085755562C2780829032 @default.
• W2085755562 hasConceptScore W2085755562C40465926 @default.
• W2085755562 hasConceptScore W2085755562C41008148 @default.
• W2085755562 hasConceptScore W2085755562C41625074 @default.
• W2085755562 hasConceptScore W2085755562C540031477 @default.
• W2085755562 hasConceptScore W2085755562C55493867 @default.
• W2085755562 hasConceptScore W2085755562C58732023 @default.
• W2085755562 hasConceptScore W2085755562C71240020 @default.
• W2085755562 hasConceptScore W2085755562C71924100 @default.
• W2085755562 hasConceptScore W2085755562C86803240 @default.
• W2085755562 hasConceptScore W2085755562C98274493 @default.
• W2085755562 hasLocation W20857555621 @default.
• W2085755562 hasLocation W20857555622 @default.
• W2085755562 hasOpenAccess W2085755562 @default.
• W2085755562 hasPrimaryLocation W20857555621 @default.
• W2085755562 hasRelatedWork W1997342359 @default.
• W2085755562 hasRelatedWork W2000084765 @default.
• W2085755562 hasRelatedWork W2029150774 @default.
• W2085755562 hasRelatedWork W2030500866 @default.
• W2085755562 hasRelatedWork W2032657822 @default.
• W2085755562 hasRelatedWork W2067099396 @default.
• W2085755562 hasRelatedWork W2085731676 @default.
• W2085755562 hasRelatedWork W2156567718 @default.
• W2085755562 hasRelatedWork W2414531608 @default.

• next