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- W2085785537 abstract "Spinal cord injury (SCI) is a devastating condition. Melatonin supplementation has been shown to lessen SCI, but its use has been limited by its side effect profile. In this work, rats underwent a moderate-to-severe contussional SCI with either placebo or beta-methyl-6-chloromelatonin, 10mg/kg or 100mg/kg supplementation. The 10mg/kg supplementation demonstrated benefit; the 100mg/kg dosage was limited by toxicity. This is the first work to assess a melatonin analog in SCI." @default.
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- W2085785537 date "2010-06-01" @default.
- W2085785537 modified "2023-10-14" @default.
- W2085785537 title "Melatonin-analog, β-methyl-6-chloromelatonin, supplementation in spinal cord injury" @default.
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- W2085785537 doi "https://doi.org/10.1016/j.brainres.2010.04.047" @default.
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