FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085792148> ?p ?o ?g. }

• W2085792148 endingPage "39" @default.
• W2085792148 startingPage "39" @default.
• W2085792148 abstract "The neurofibromatoses comprise at least two autosomal dominant disorders affecting an estimated 100,000 Americans with clinical manifestations that may require care from every type of clinician. Neurofibromatosis 1 and neurofibromatosis 2 have in common the occurrence of many neurofibromas but are distinctly different clinical disorders. The disease genes are on different chromosomes. Magnetic resonance imaging, particularly with gadolinium enhancement, has generally supplanted other techniques for visualizing brain, spinal, and other neural tumors in both disorders. The technique has rekindled the controversy over the nature and frequency of optic pathway tumors in patients with neurofibromatosis 1 and has revealed, throughout the brains of young patients, bright lesions that have uncertain clinical consequences and unknown pathologic bases. In patients with neurofibromatosis 2, small acoustic neuromas can be seen, leading to the possibility of excision with preservation of hearing and facial nerve function. Abnormal hearing may occur to excess in patients with neurofibromatosis 1, but acoustic neuroma has never been documented. In patients with neurofibromatosis 2, a battery of audiologic tests has a high positive predictive power. Lisch nodules or iris hamartomas, probably a universal sign in adults with the neurofibromatosis 1 gene, cause no problem with vision. Posterior capsular lens opacity in patients with neurofibromatosis 2 is a helpful diagnostic sign and a potential source of additional handicap in persons at risk for impaired hearing. Progress in the clinical delineation of the disorders has been matched with considerable research into the still obscure pathogenesis of the disorders. Such rapid advances may necessitate reconsideration of the conclusions of the National Institutes of Health Consensus Development Conference on Neurofibromatosis, especially those on the categories of persons in which a neurofibromatosis should be considered and the need for caution in recommending surgery. Watchful waiting may often be the best management for acoustic neuromas in neurofibromatosis 2." @default.
• W2085792148 created "2016-06-24" @default.
• W2085792148 creator A5010160621 @default.
• W2085792148 creator A5018025232 @default.
• W2085792148 creator A5018123003 @default.
• W2085792148 creator A5023876960 @default.
• W2085792148 creator A5024205592 @default.
• W2085792148 creator A5025873792 @default.
• W2085792148 date "1990-07-01" @default.
• W2085792148 modified "2023-10-05" @default.
• W2085792148 title "Neurofibromatosis 1 (Recklinghausen Disease) and Neurofibromatosis 2 (Bilateral Acoustic Neurofibromatosis)" @default.
• W2085792148 cites W135244689 @default.
• W2085792148 cites W13808466 @default.
• W2085792148 cites W148356229 @default.
• W2085792148 cites W1646559883 @default.
• W2085792148 cites W187780743 @default.
• W2085792148 cites W1963514792 @default.
• W2085792148 cites W1967817139 @default.
• W2085792148 cites W1972169090 @default.
• W2085792148 cites W1972651910 @default.
• W2085792148 cites W1978591477 @default.
• W2085792148 cites W1981521768 @default.
• W2085792148 cites W1984895411 @default.
• W2085792148 cites W1990880437 @default.
• W2085792148 cites W1995822744 @default.
• W2085792148 cites W1995971741 @default.
• W2085792148 cites W2004451941 @default.
• W2085792148 cites W2006140298 @default.
• W2085792148 cites W2006293244 @default.
• W2085792148 cites W2007012469 @default.
• W2085792148 cites W2011276874 @default.
• W2085792148 cites W2011718957 @default.
• W2085792148 cites W2012520870 @default.
• W2085792148 cites W2015546181 @default.
• W2085792148 cites W2017221392 @default.
• W2085792148 cites W2033725075 @default.
• W2085792148 cites W2038029714 @default.
• W2085792148 cites W2040393103 @default.
• W2085792148 cites W2042949664 @default.
• W2085792148 cites W2054223973 @default.
• W2085792148 cites W2054778208 @default.
• W2085792148 cites W2056098015 @default.
• W2085792148 cites W2059864970 @default.
• W2085792148 cites W2064569909 @default.
• W2085792148 cites W2067566670 @default.
• W2085792148 cites W2070452292 @default.
• W2085792148 cites W2070556454 @default.
• W2085792148 cites W2070898935 @default.
• W2085792148 cites W2073177933 @default.
• W2085792148 cites W2077858999 @default.
• W2085792148 cites W2083000224 @default.
• W2085792148 cites W2084749103 @default.
• W2085792148 cites W2089023484 @default.
• W2085792148 cites W2090040363 @default.
• W2085792148 cites W2098353832 @default.
• W2085792148 cites W2110306553 @default.
• W2085792148 cites W2119963105 @default.
• W2085792148 cites W2123992733 @default.
• W2085792148 cites W2131532433 @default.
• W2085792148 cites W2136208548 @default.
• W2085792148 cites W2136402263 @default.
• W2085792148 cites W2139478740 @default.
• W2085792148 cites W2144937536 @default.
• W2085792148 cites W2147282725 @default.
• W2085792148 cites W2154840445 @default.
• W2085792148 cites W2157590686 @default.
• W2085792148 cites W2160253451 @default.
• W2085792148 cites W2161024497 @default.
• W2085792148 cites W2167429859 @default.
• W2085792148 cites W2367931694 @default.
• W2085792148 cites W2404449824 @default.
• W2085792148 cites W2409250911 @default.
• W2085792148 cites W2409694118 @default.
• W2085792148 cites W2415494887 @default.
• W2085792148 cites W2416382978 @default.
• W2085792148 cites W2442971841 @default.
• W2085792148 cites W2471154971 @default.
• W2085792148 cites W2472729923 @default.
• W2085792148 cites W2473971750 @default.
• W2085792148 cites W27458055 @default.
• W2085792148 cites W2916302001 @default.
• W2085792148 cites W2993007362 @default.
• W2085792148 cites W2998532160 @default.
• W2085792148 doi "https://doi.org/10.7326/0003-4819-113-1-39" @default.
• W2085792148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2112353" @default.
• W2085792148 hasPublicationYear "1990" @default.
• W2085792148 type Work @default.
• W2085792148 sameAs 2085792148 @default.
• W2085792148 citedByCount "384" @default.
• W2085792148 countsByYear W20857921482012 @default.
• W2085792148 countsByYear W20857921482013 @default.
• W2085792148 countsByYear W20857921482014 @default.
• W2085792148 countsByYear W20857921482015 @default.
• W2085792148 countsByYear W20857921482016 @default.
• W2085792148 countsByYear W20857921482017 @default.
• W2085792148 countsByYear W20857921482018 @default.
• W2085792148 countsByYear W20857921482019 @default.
• W2085792148 countsByYear W20857921482020 @default.

• next