FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085802677> ?p ?o ?g. }

• W2085802677 endingPage "800" @default.
• W2085802677 startingPage "789" @default.
• W2085802677 abstract "Summary Purpose: Herein we used electrophysiologic approaches in hippocampal area CA1 to estimate how morphine treatment alters the pentylenetetrazol (PTZ) effects. Methods: Hippocampal slices taken from either control animals or animals made dependent via chronic morphine administration were examined. Changes in the population spike and epileptiform amplitudes were used as indices to quantify the effects of PTZ exposure in the control and morphine‐dependent slices. Hippocampal slices taken either from control animals or from animals made dependent upon morphine were exposed to PTZ, either with or without morphine, naloxone, or morphine + naloxone. Results: Morphine dependence increased a PTZ‐induced long‐term potentiation (LTP) of the population spike in CA1 in vitro. This LTP was not found in rats that had spontaneously withdrawn morphine or withdrawn with naloxone in vivo after chronic morphine intake. Morphine or naloxone in vitro blocked the PTZ‐induced LTP changes in control and morphine‐dependent slices. However, PTZ‐induced multiple population spikes (epileptiform activity) in CA1 was not blocked by naloxone. Discussion: It is concluded that dependence on morphine enhances PTZ‐induced plastic and epileptic changes in CA1 excitability. We suggest that this model of neuronal activity in dependent slices could present an opportunity for studying the mechanisms underlying the increased likelihood of seizures in morphine users." @default.
• W2085802677 created "2016-06-24" @default.
• W2085802677 creator A5019820229 @default.
• W2085802677 creator A5022549445 @default.
• W2085802677 creator A5025691884 @default.
• W2085802677 creator A5039265302 @default.
• W2085802677 creator A5069408646 @default.
• W2085802677 creator A5085877918 @default.
• W2085802677 date "2009-04-01" @default.
• W2085802677 modified "2023-10-18" @default.
• W2085802677 title "Morphine dependence increases the response to a brief pentylenetetrazol administration in rat hippocampal CA1 in vitro" @default.
• W2085802677 cites W1635366883 @default.
• W2085802677 cites W1779015127 @default.
• W2085802677 cites W1948495312 @default.
• W2085802677 cites W1964448684 @default.
• W2085802677 cites W1967574025 @default.
• W2085802677 cites W1975688895 @default.
• W2085802677 cites W1983585961 @default.
• W2085802677 cites W1985031395 @default.
• W2085802677 cites W1996436004 @default.
• W2085802677 cites W2007164600 @default.
• W2085802677 cites W2021275507 @default.
• W2085802677 cites W2025851571 @default.
• W2085802677 cites W2030712088 @default.
• W2085802677 cites W2032963527 @default.
• W2085802677 cites W2033188497 @default.
• W2085802677 cites W2033525233 @default.
• W2085802677 cites W2035767489 @default.
• W2085802677 cites W2036960054 @default.
• W2085802677 cites W2038913711 @default.
• W2085802677 cites W2040762837 @default.
• W2085802677 cites W2044497591 @default.
• W2085802677 cites W2045121272 @default.
• W2085802677 cites W2052581573 @default.
• W2085802677 cites W2053996061 @default.
• W2085802677 cites W2055354134 @default.
• W2085802677 cites W2060229995 @default.
• W2085802677 cites W2060432426 @default.
• W2085802677 cites W2064094695 @default.
• W2085802677 cites W2070551672 @default.
• W2085802677 cites W2076166321 @default.
• W2085802677 cites W2081856273 @default.
• W2085802677 cites W2091881805 @default.
• W2085802677 cites W2137501215 @default.
• W2085802677 cites W2142845018 @default.
• W2085802677 cites W2155585976 @default.
• W2085802677 cites W2170971246 @default.
• W2085802677 cites W2172734677 @default.
• W2085802677 cites W2235256472 @default.
• W2085802677 cites W2302128506 @default.
• W2085802677 cites W2338187089 @default.
• W2085802677 doi "https://doi.org/10.1111/j.1528-1167.2008.01802.x" @default.
• W2085802677 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19183220" @default.
• W2085802677 hasPublicationYear "2009" @default.
• W2085802677 type Work @default.
• W2085802677 sameAs 2085802677 @default.
• W2085802677 citedByCount "2" @default.
• W2085802677 countsByYear W20858026772012 @default.
• W2085802677 countsByYear W20858026772013 @default.
• W2085802677 crossrefType "journal-article" @default.
• W2085802677 hasAuthorship W2085802677A5019820229 @default.
• W2085802677 hasAuthorship W2085802677A5022549445 @default.
• W2085802677 hasAuthorship W2085802677A5025691884 @default.
• W2085802677 hasAuthorship W2085802677A5039265302 @default.
• W2085802677 hasAuthorship W2085802677A5069408646 @default.
• W2085802677 hasAuthorship W2085802677A5085877918 @default.
• W2085802677 hasConcept C126322002 @default.
• W2085802677 hasConcept C148762608 @default.
• W2085802677 hasConcept C15744967 @default.
• W2085802677 hasConcept C169760540 @default.
• W2085802677 hasConcept C170493617 @default.
• W2085802677 hasConcept C185592680 @default.
• W2085802677 hasConcept C25274449 @default.
• W2085802677 hasConcept C2775858608 @default.
• W2085802677 hasConcept C2776464000 @default.
• W2085802677 hasConcept C2776819090 @default.
• W2085802677 hasConcept C2777389121 @default.
• W2085802677 hasConcept C2778186239 @default.
• W2085802677 hasConcept C2778750930 @default.
• W2085802677 hasConcept C2779277159 @default.
• W2085802677 hasConcept C2781063702 @default.
• W2085802677 hasConcept C2908647359 @default.
• W2085802677 hasConcept C71924100 @default.
• W2085802677 hasConcept C98274493 @default.
• W2085802677 hasConcept C99454951 @default.
• W2085802677 hasConceptScore W2085802677C126322002 @default.
• W2085802677 hasConceptScore W2085802677C148762608 @default.
• W2085802677 hasConceptScore W2085802677C15744967 @default.
• W2085802677 hasConceptScore W2085802677C169760540 @default.
• W2085802677 hasConceptScore W2085802677C170493617 @default.
• W2085802677 hasConceptScore W2085802677C185592680 @default.
• W2085802677 hasConceptScore W2085802677C25274449 @default.
• W2085802677 hasConceptScore W2085802677C2775858608 @default.
• W2085802677 hasConceptScore W2085802677C2776464000 @default.
• W2085802677 hasConceptScore W2085802677C2776819090 @default.
• W2085802677 hasConceptScore W2085802677C2777389121 @default.
• W2085802677 hasConceptScore W2085802677C2778186239 @default.
• W2085802677 hasConceptScore W2085802677C2778750930 @default.

• next