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- W2085804559 abstract "IN 1958, Silbermann et al described a new ulcerogenic procedure in the dog in which a 15 to 40 cm loop of ileum is interposed isoperistaltically in the first portion of the duodenum. Seven of nine such animals developed chronic ulcers in the ileal segment within 4 mo. The mechanism of the ulceration is uncertain. However, since the preparation does not require interference with upper gastrointestinal continuity, does not produce nutritional deficits, and does not require the administration of drugs with other systemic side effects, the authors pointed out that it is ideal for the unbiased evaluation of surgical procedures for peptic ulcer. The following experiment was designed 1 to evaluate the ileal interposition operation as a predictable ulcerogenic preparation and 2 to contrast the protective effect of vagotomy and pyloroplasty with vagotomy and antrectomy in the development of this type of ulceration. Methods Healthy mongrel dogs weighing 8 to" @default.
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- W2085804559 date "1963-03-23" @default.
- W2085804559 modified "2023-09-25" @default.
- W2085804559 title "Pyloroplasty or Antrectomy with Vagotomy in Ulcerogenic Ileal Interposition" @default.
- W2085804559 doi "https://doi.org/10.1001/jama.1963.63700120004009a" @default.
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