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• W2085812488 abstract "Biology and strain variation in the causative agent of hydatid disease is reviewed with emphasis on developmental and genetic aspects. In vitro cultivation experiments have made a significant contribution to current knowledge of the developmental plasticity of Echinococcus. However, the mechanisms which regulate and determine developmental strategies in the parasite, as well as the characteristics, source and cytodifierentiation of germinal cells, are not understood. The nature, significance and origin of strain variation in Echinococcus are examined. Before we can fully appreciate the phenotypic consequences of genetic differentiation between populations, we need to know something about the genetic and environmental components of variation in traits such as development rate, host preference, host specificity, virulence and drug resistance. There is an urgent need for research on the developmental pathways by which genetic differences within and between strains of E. granulosus are translated to phenotypic differences in these traits." @default.
• W2085812488 created "2016-06-24" @default.
• W2085812488 creator A5054748956 @default.
• W2085812488 creator A5086296060 @default.
• W2085812488 date "1990-07-01" @default.
• W2085812488 modified "2023-09-24" @default.
• W2085812488 title "Echinococcus: Biology and strain variation" @default.
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• W2085812488 doi "https://doi.org/10.1016/0020-7519(90)90193-q" @default.
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