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- W2085853745 abstract "The effect of exenatide in weight loss has been reported. Presented here is a case of a morbidly obese patient with type 2 diabetes using exenatide who dramatically lost her body weight in a year and experienced improved glycemic control. Exenatide therapy was initiated for a 59-year-old morbidly obese Japanese woman with type 2 diabetes. To examine the effects of the exenatide treatment, continuous glucose monitoring was performed, and blood was drawn at 0, 30, 60, 120, and 180 min after breakfast to measure insulin, glucagon, glucagon-like peptide-1 (GLP-1), and glucose-dependent insulinotropic peptide (GIP) levels. After 1 year of exenatide therapy, the patient lost 37.5 kg, her glycemic control improved, and her insulin sensitivity recovered. The patient’s levels of insulin, glucagon, active GLP-1, and total GIP also decreased after 1 year of exenatide treatment. The exenatide treatment was effective for reducing body weight and improving glycemic control. After 1 year of exenatide treatment, decreased glucagon, active GLP-1, and total GIP levels were observed following a meal, suggesting that exenatide might affect these hormonal reactions." @default.
- W2085853745 created "2016-06-24" @default.
- W2085853745 creator A5017888890 @default.
- W2085853745 creator A5036516738 @default.
- W2085853745 date "2014-01-18" @default.
- W2085853745 modified "2023-10-18" @default.
- W2085853745 title "Effects of Exenatide in a Morbidly Obese Patient with Type 2 Diabetes" @default.
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- W2085853745 doi "https://doi.org/10.1007/s13300-014-0050-6" @default.
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