FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085981262> ?p ?o ?g. }

• W2085981262 endingPage "485" @default.
• W2085981262 startingPage "478" @default.
• W2085981262 abstract "The aim of the present work was to develop spherical agglomerates and solid dispersions of silymarin in the presence of polyvinyl pyrrolidone. Silymarin and its products were characterized in terms of morphology, particle size, solubility, dissolution study, differential scanning calorimetry and Fourier transforms infra red spectroscopy. The therapeutic effects of optimized silymarin products compared to a commercially available silymarin were assessed by determining biochemical parameters and histopathological properties of the different silymarin products against carbon tetrachloride (CCL4)-induced hepatotoxicity in rats. SEM studies showed that agglomerates were spherical in shape. Silymarin agglomerates (in presence of 0.75 % PVP k-30) and solid dispersion with PVP k-30, 1:8 w/w exhibited better dissolution results and significantly reduced carbon tetrachloride-induced hepatotoxicity compared to its commercial product. In conclusion, spherical agglomeration and solid dispersion could be useful techniques for delivery of poorly water-soluble silymarin while affording excellent hepatic therapy." @default.
• W2085981262 created "2016-06-24" @default.
• W2085981262 creator A5002381786 @default.
• W2085981262 creator A5056949476 @default.
• W2085981262 date "2014-01-01" @default.
• W2085981262 modified "2023-10-18" @default.
• W2085981262 title "Spherical agglomeration versus solid dispersion as different trials to optimize dissolution and bioactivity of silymarin" @default.
• W2085981262 cites W1963837413 @default.
• W2085981262 cites W1968667721 @default.
• W2085981262 cites W1977431523 @default.
• W2085981262 cites W1977955397 @default.
• W2085981262 cites W1979209041 @default.
• W2085981262 cites W1982315739 @default.
• W2085981262 cites W2004939027 @default.
• W2085981262 cites W2015404896 @default.
• W2085981262 cites W2023812434 @default.
• W2085981262 cites W2033799761 @default.
• W2085981262 cites W2034758007 @default.
• W2085981262 cites W2037669981 @default.
• W2085981262 cites W2051621165 @default.
• W2085981262 cites W2062307889 @default.
• W2085981262 cites W2066504688 @default.
• W2085981262 cites W2068188324 @default.
• W2085981262 cites W2070156676 @default.
• W2085981262 cites W2074409504 @default.
• W2085981262 cites W2076708571 @default.
• W2085981262 cites W2082797213 @default.
• W2085981262 cites W2086434450 @default.
• W2085981262 cites W2090688263 @default.
• W2085981262 cites W2095177675 @default.
• W2085981262 cites W2100520064 @default.
• W2085981262 cites W2115538851 @default.
• W2085981262 cites W2141569620 @default.
• W2085981262 cites W2143641481 @default.
• W2085981262 cites W2151114776 @default.
• W2085981262 cites W2151200192 @default.
• W2085981262 cites W2157335302 @default.
• W2085981262 cites W2169009969 @default.
• W2085981262 cites W2315253121 @default.
• W2085981262 doi "https://doi.org/10.1016/s1773-2247(14)50091-3" @default.
• W2085981262 hasPublicationYear "2014" @default.
• W2085981262 type Work @default.
• W2085981262 sameAs 2085981262 @default.
• W2085981262 citedByCount "14" @default.
• W2085981262 countsByYear W20859812622016 @default.
• W2085981262 countsByYear W20859812622018 @default.
• W2085981262 countsByYear W20859812622019 @default.
• W2085981262 countsByYear W20859812622020 @default.
• W2085981262 countsByYear W20859812622021 @default.
• W2085981262 countsByYear W20859812622022 @default.
• W2085981262 countsByYear W20859812622023 @default.
• W2085981262 crossrefType "journal-article" @default.
• W2085981262 hasAuthorship W2085981262A5002381786 @default.
• W2085981262 hasAuthorship W2085981262A5056949476 @default.
• W2085981262 hasConcept C120665830 @default.
• W2085981262 hasConcept C121332964 @default.
• W2085981262 hasConcept C127413603 @default.
• W2085981262 hasConcept C129955480 @default.
• W2085981262 hasConcept C131850264 @default.
• W2085981262 hasConcept C13965031 @default.
• W2085981262 hasConcept C155574463 @default.
• W2085981262 hasConcept C159985019 @default.
• W2085981262 hasConcept C160892712 @default.
• W2085981262 hasConcept C177562468 @default.
• W2085981262 hasConcept C178790620 @default.
• W2085981262 hasConcept C185592680 @default.
• W2085981262 hasConcept C187530423 @default.
• W2085981262 hasConcept C192562407 @default.
• W2085981262 hasConcept C2777359374 @default.
• W2085981262 hasConcept C39519442 @default.
• W2085981262 hasConcept C42360764 @default.
• W2085981262 hasConcept C88380143 @default.
• W2085981262 hasConcept C97355855 @default.
• W2085981262 hasConceptScore W2085981262C120665830 @default.
• W2085981262 hasConceptScore W2085981262C121332964 @default.
• W2085981262 hasConceptScore W2085981262C127413603 @default.
• W2085981262 hasConceptScore W2085981262C129955480 @default.
• W2085981262 hasConceptScore W2085981262C131850264 @default.
• W2085981262 hasConceptScore W2085981262C13965031 @default.
• W2085981262 hasConceptScore W2085981262C155574463 @default.
• W2085981262 hasConceptScore W2085981262C159985019 @default.
• W2085981262 hasConceptScore W2085981262C160892712 @default.
• W2085981262 hasConceptScore W2085981262C177562468 @default.
• W2085981262 hasConceptScore W2085981262C178790620 @default.
• W2085981262 hasConceptScore W2085981262C185592680 @default.
• W2085981262 hasConceptScore W2085981262C187530423 @default.
• W2085981262 hasConceptScore W2085981262C192562407 @default.
• W2085981262 hasConceptScore W2085981262C2777359374 @default.
• W2085981262 hasConceptScore W2085981262C39519442 @default.
• W2085981262 hasConceptScore W2085981262C42360764 @default.
• W2085981262 hasConceptScore W2085981262C88380143 @default.
• W2085981262 hasConceptScore W2085981262C97355855 @default.
• W2085981262 hasIssue "5" @default.
• W2085981262 hasLocation W20859812621 @default.
• W2085981262 hasOpenAccess W2085981262 @default.
• W2085981262 hasPrimaryLocation W20859812621 @default.
• W2085981262 hasRelatedWork W1908117345 @default.
• W2085981262 hasRelatedWork W1977424460 @default.

• next