Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085984718> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2085984718 endingPage "72" @default.
- W2085984718 startingPage "63" @default.
- W2085984718 abstract "To elucidate the mechanism of epileptogenesis, seizures were investigated in the EL mouse, which is an excellent model for epilepsy. In these mice, epileptic seizures initiate in the parietal cortex, where markers of GABA-mediated inhibition are reduced compared with the parietal cortex of DDY mice (the parent strain). This is the first report on units of neuronal activity in the parietal cortex of EL and DDY mice (14 each) using an extracellular microelectrode in vivo under moderate pentobarbital anesthesia. The parietal cortex neurons of the EL mice were less active at rest than those of the DDY mice, but they responded more actively to proprioceptive afferent input from muscle stimulation than the DDY neurons. Three types of spontaneous firing were classified in both EL and DDY cortical neurons: periodically firing, Type A; continuously firing, Type B; and random firing, Type C. The proportions of these three types of neurons were almost the same in the EL mice as in the DDY mice. The peak frequency of the periodical cycle of Type A neurons in the EL mice (375 ms) was longer than that of the Type A neurons in the DDY mice (225 ms). Four patterns of responses to stimulation were observed in the parietal cortex neurons. More excitatory patterns were observed in the EL mice than in the DDY mice. The trans-laminar distribution of cells with different response patterns was also different between the EL and DDY mice. These characteristics of parietal cortex neurons may help determine the seizure susceptibility or ictogenesis in EL mice because the mechanisms underlying these patterns could provide the basis for hypersynchronized discharges in epileptic seizures." @default.
- W2085984718 created "2016-06-24" @default.
- W2085984718 creator A5015708987 @default.
- W2085984718 creator A5017614301 @default.
- W2085984718 creator A5035597935 @default.
- W2085984718 creator A5038407507 @default.
- W2085984718 creator A5084446491 @default.
- W2085984718 date "2012-06-01" @default.
- W2085984718 modified "2023-09-23" @default.
- W2085984718 title "Neuronal activity in the parietal cortex of EL and DDY mice" @default.
- W2085984718 cites W1966418869 @default.
- W2085984718 cites W1973171658 @default.
- W2085984718 cites W2006816318 @default.
- W2085984718 cites W2019938722 @default.
- W2085984718 cites W2023870062 @default.
- W2085984718 cites W2025093063 @default.
- W2085984718 cites W2026301332 @default.
- W2085984718 cites W2027726856 @default.
- W2085984718 cites W2030873735 @default.
- W2085984718 cites W2037105965 @default.
- W2085984718 cites W2038222038 @default.
- W2085984718 cites W2038879792 @default.
- W2085984718 cites W2040170158 @default.
- W2085984718 cites W2054930781 @default.
- W2085984718 cites W2057049846 @default.
- W2085984718 cites W2079173805 @default.
- W2085984718 cites W2082085062 @default.
- W2085984718 cites W2096519870 @default.
- W2085984718 cites W2117329255 @default.
- W2085984718 cites W2606728372 @default.
- W2085984718 cites W2067284446 @default.
- W2085984718 doi "https://doi.org/10.1016/j.brainres.2012.03.051" @default.
- W2085984718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22578359" @default.
- W2085984718 hasPublicationYear "2012" @default.
- W2085984718 type Work @default.
- W2085984718 sameAs 2085984718 @default.
- W2085984718 citedByCount "3" @default.
- W2085984718 countsByYear W20859847182013 @default.
- W2085984718 countsByYear W20859847182014 @default.
- W2085984718 countsByYear W20859847182016 @default.
- W2085984718 crossrefType "journal-article" @default.
- W2085984718 hasAuthorship W2085984718A5015708987 @default.
- W2085984718 hasAuthorship W2085984718A5017614301 @default.
- W2085984718 hasAuthorship W2085984718A5035597935 @default.
- W2085984718 hasAuthorship W2085984718A5038407507 @default.
- W2085984718 hasAuthorship W2085984718A5084446491 @default.
- W2085984718 hasConcept C112592302 @default.
- W2085984718 hasConcept C126322002 @default.
- W2085984718 hasConcept C169760540 @default.
- W2085984718 hasConcept C17077164 @default.
- W2085984718 hasConcept C172497186 @default.
- W2085984718 hasConcept C24998067 @default.
- W2085984718 hasConcept C2776755955 @default.
- W2085984718 hasConcept C2777348757 @default.
- W2085984718 hasConcept C2778186239 @default.
- W2085984718 hasConcept C2781041448 @default.
- W2085984718 hasConcept C57236427 @default.
- W2085984718 hasConcept C6757342 @default.
- W2085984718 hasConcept C71924100 @default.
- W2085984718 hasConcept C86803240 @default.
- W2085984718 hasConceptScore W2085984718C112592302 @default.
- W2085984718 hasConceptScore W2085984718C126322002 @default.
- W2085984718 hasConceptScore W2085984718C169760540 @default.
- W2085984718 hasConceptScore W2085984718C17077164 @default.
- W2085984718 hasConceptScore W2085984718C172497186 @default.
- W2085984718 hasConceptScore W2085984718C24998067 @default.
- W2085984718 hasConceptScore W2085984718C2776755955 @default.
- W2085984718 hasConceptScore W2085984718C2777348757 @default.
- W2085984718 hasConceptScore W2085984718C2778186239 @default.
- W2085984718 hasConceptScore W2085984718C2781041448 @default.
- W2085984718 hasConceptScore W2085984718C57236427 @default.
- W2085984718 hasConceptScore W2085984718C6757342 @default.
- W2085984718 hasConceptScore W2085984718C71924100 @default.
- W2085984718 hasConceptScore W2085984718C86803240 @default.
- W2085984718 hasLocation W20859847181 @default.
- W2085984718 hasLocation W20859847182 @default.
- W2085984718 hasOpenAccess W2085984718 @default.
- W2085984718 hasPrimaryLocation W20859847181 @default.
- W2085984718 hasRelatedWork W1462465093 @default.
- W2085984718 hasRelatedWork W1988764473 @default.
- W2085984718 hasRelatedWork W2012315399 @default.
- W2085984718 hasRelatedWork W2023537822 @default.
- W2085984718 hasRelatedWork W2041029303 @default.
- W2085984718 hasRelatedWork W2094818911 @default.
- W2085984718 hasRelatedWork W2122268201 @default.
- W2085984718 hasRelatedWork W2395798449 @default.
- W2085984718 hasRelatedWork W2396923619 @default.
- W2085984718 hasRelatedWork W2408985066 @default.
- W2085984718 hasVolume "1460" @default.
- W2085984718 isParatext "false" @default.
- W2085984718 isRetracted "false" @default.
- W2085984718 magId "2085984718" @default.
- W2085984718 workType "article" @default.