FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2085987834> ?p ?o ?g. }

• W2085987834 endingPage "333" @default.
• W2085987834 startingPage "326" @default.
• W2085987834 abstract "Context: Bacterial ureases play an important role in pathogenesis of urinary infections. Selection of plants was done on the basis of their uses by the local people for the treatment of various bacterial and urinary infections.Objective: Our investigation screens and evaluates 15 Indian medicinal plants for their possible urease inhibitory activity as well as their ability to inhibit bacteria causing urinary infections.Materials and methods: Plant extracts in three different solvents (methanol, aqueous, and cow urine) were screened for their effect on Jack-bean urease using the phenol–hypochlorite method. Subsequently, seven bacterial strains were screened for their ability to release urease and further antimicrobial-linked urease inhibition activity and minimum inhibitory concentration of the tested extracts were evaluated by the agar well diffusion and microdilution method, respectively.Results: Five plants out of 15 crude extracts revealed good urease inhibitory activity (≥20% at 1 mg/ml conc.) and IC50 values for these extracts ranged from 2.77 to 0.70 mg/ml. Further testing of these extracts on urease-producing bacterial strains (Staphylococcus aureus NCDC 109, S. aureus MTCC 3160, Proteus vulgaris MTCC 426, Klebsiella pneumoniae MTCC 4030, and Pseudomonas aeruginosa MTCC 7453) showed good anti-urease potency with an MIC ranging from 500 to 7.3 µg/ml.Discussion and conclusion: The results of screening as well as susceptibility assay clearly revealed a strong urease inhibitory effect of Acacia nilotica L. (Fabaceae), Emblica officinalis Gaertn. (Phyllanthaceae), Psidium guajava L. (Myrtaceae), Rosa indica L. (Rosaceae), and Terminalia chebula Retz. (Combretaceae). Our findings may help to explain the beneficial effect of these plants against infections associated with the urease enzyme." @default.
• W2085987834 created "2016-06-24" @default.
• W2085987834 creator A5003975269 @default.
• W2085987834 creator A5025112956 @default.
• W2085987834 creator A5044747649 @default.
• W2085987834 creator A5075575631 @default.
• W2085987834 creator A5086258321 @default.
• W2085987834 date "2014-11-04" @default.
• W2085987834 modified "2023-09-27" @default.
• W2085987834 title "<i>In vitro</i>screening and evaluation of some Indian medicinal plants for their potential to inhibit Jack bean and bacterial ureases causing urinary infections" @default.
• W2085987834 cites W2008780443 @default.
• W2085987834 cites W2035349225 @default.
• W2085987834 cites W2046588215 @default.
• W2085987834 cites W2060512903 @default.
• W2085987834 cites W2067998161 @default.
• W2085987834 cites W2072142218 @default.
• W2085987834 cites W2081047141 @default.
• W2085987834 cites W2093711226 @default.
• W2085987834 cites W2104276052 @default.
• W2085987834 cites W2110590245 @default.
• W2085987834 cites W2111030334 @default.
• W2085987834 cites W2140817750 @default.
• W2085987834 cites W2149591934 @default.
• W2085987834 cites W2157811231 @default.
• W2085987834 cites W2160810152 @default.
• W2085987834 cites W2952370498 @default.
• W2085987834 cites W4211017205 @default.
• W2085987834 cites W4239747192 @default.
• W2085987834 doi "https://doi.org/10.3109/13880209.2014.918158" @default.
• W2085987834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25366133" @default.
• W2085987834 hasPublicationYear "2014" @default.
• W2085987834 type Work @default.
• W2085987834 sameAs 2085987834 @default.
• W2085987834 citedByCount "19" @default.
• W2085987834 countsByYear W20859878342015 @default.
• W2085987834 countsByYear W20859878342016 @default.
• W2085987834 countsByYear W20859878342017 @default.
• W2085987834 countsByYear W20859878342018 @default.
• W2085987834 countsByYear W20859878342019 @default.
• W2085987834 countsByYear W20859878342020 @default.
• W2085987834 countsByYear W20859878342021 @default.
• W2085987834 countsByYear W20859878342022 @default.
• W2085987834 countsByYear W20859878342023 @default.
• W2085987834 crossrefType "journal-article" @default.
• W2085987834 hasAuthorship W2085987834A5003975269 @default.
• W2085987834 hasAuthorship W2085987834A5025112956 @default.
• W2085987834 hasAuthorship W2085987834A5044747649 @default.
• W2085987834 hasAuthorship W2085987834A5075575631 @default.
• W2085987834 hasAuthorship W2085987834A5086258321 @default.
• W2085987834 hasBestOaLocation W20859878341 @default.
• W2085987834 hasConcept C181199279 @default.
• W2085987834 hasConcept C185592680 @default.
• W2085987834 hasConcept C2778039505 @default.
• W2085987834 hasConcept C2779489039 @default.
• W2085987834 hasConcept C2779521917 @default.
• W2085987834 hasConcept C2780096663 @default.
• W2085987834 hasConcept C2780662933 @default.
• W2085987834 hasConcept C2780886089 @default.
• W2085987834 hasConcept C3020366999 @default.
• W2085987834 hasConcept C4937899 @default.
• W2085987834 hasConcept C523546767 @default.
• W2085987834 hasConcept C54355233 @default.
• W2085987834 hasConcept C55493867 @default.
• W2085987834 hasConcept C556039675 @default.
• W2085987834 hasConcept C71924100 @default.
• W2085987834 hasConcept C86803240 @default.
• W2085987834 hasConcept C89423630 @default.
• W2085987834 hasConceptScore W2085987834C181199279 @default.
• W2085987834 hasConceptScore W2085987834C185592680 @default.
• W2085987834 hasConceptScore W2085987834C2778039505 @default.
• W2085987834 hasConceptScore W2085987834C2779489039 @default.
• W2085987834 hasConceptScore W2085987834C2779521917 @default.
• W2085987834 hasConceptScore W2085987834C2780096663 @default.
• W2085987834 hasConceptScore W2085987834C2780662933 @default.
• W2085987834 hasConceptScore W2085987834C2780886089 @default.
• W2085987834 hasConceptScore W2085987834C3020366999 @default.
• W2085987834 hasConceptScore W2085987834C4937899 @default.
• W2085987834 hasConceptScore W2085987834C523546767 @default.
• W2085987834 hasConceptScore W2085987834C54355233 @default.
• W2085987834 hasConceptScore W2085987834C55493867 @default.
• W2085987834 hasConceptScore W2085987834C556039675 @default.
• W2085987834 hasConceptScore W2085987834C71924100 @default.
• W2085987834 hasConceptScore W2085987834C86803240 @default.
• W2085987834 hasConceptScore W2085987834C89423630 @default.
• W2085987834 hasIssue "3" @default.
• W2085987834 hasLocation W20859878341 @default.
• W2085987834 hasLocation W20859878342 @default.
• W2085987834 hasOpenAccess W2085987834 @default.
• W2085987834 hasPrimaryLocation W20859878341 @default.
• W2085987834 hasRelatedWork W1543039379 @default.
• W2085987834 hasRelatedWork W2084133606 @default.
• W2085987834 hasRelatedWork W2085987834 @default.
• W2085987834 hasRelatedWork W2092919505 @default.
• W2085987834 hasRelatedWork W2425937850 @default.
• W2085987834 hasRelatedWork W2687544130 @default.
• W2085987834 hasRelatedWork W3202513798 @default.
• W2085987834 hasRelatedWork W4384568444 @default.
• W2085987834 hasRelatedWork W2186974177 @default.

• next